Abstract: Methods of controlling biological processes by altering the electric field gradient in a test chamber are disclosed. A portion of a surface of the test chamber is attached to at least one immobilized component of the biological process. Microfluidic devices capable of same are also disclosed.

Abstract: Certain examples described herein relate to splice detection. In certain cases, a splice is detected in a web being conveyed towards a transfer member of the printing system. In certain cases, a print frame is identified from a sequence of pending print frames using successive repeat lengths of the sequence and a distance of the splice from the transfer member. The identified print frame is to be transferred from the transfer member across the splice. In certain cases, writing of the identified print frame onto a photo-imaging plate of the printing system is deferred. In certain examples, the web is disengaged from the transfer member following transfer of an image of a print frame preceding the identified print frame. The web is re-engaged with the transfer member so as to transfer an image of the identified print frame to the web from the transfer member after the splice is conveyed beyond the transfer member.

Abstract: The present invention describes a community based computerized method and system which automatically gathers, acquires and collects students' usage data in a dynamic knowledge base as they perform their routine learning assignments from any educational source (e.g. printed textbooks, e-textbook etc.), for the purpose of assessing their achievements, competencies, areas of interest, preferences and requirements, and then providing automatically generated students-related information and services which are based on this knowledge, such as custom study guides, preparation plans for exams and academic skills assessment reports. The system also provides insights, trends and behavioral patterns within students' groups, which are identified and deduced from actual activities of users, such as learning habits, areas of interest, and demand for new and existing educational learning sources.

Abstract: Certain examples described herein relate to splice detection. In certain cases, a splice is detected in a web being conveyed towards a transfer member of the printing system. In certain cases, a print frame is identified from a sequence of pending print frames using successive repeat lengths of the sequence and a distance of the splice from the transfer member. The identified print frame is to be transferred from the transfer member across the splice. In certain cases, writing of the identified print frame onto a photo-imaging plate of the printing system is deferred. In certain examples, the web is disengaged from the transfer member following transfer of an image of a print frame preceding the identified print frame. The web is re-engaged with the transfer member so as to transfer an image of the identified print frame to the web from the transfer member after the splice is conveyed beyond the transfer member.

Abstract: Disclosed are various embodiments for dynamically generating a search set for use in a search application, such as a search engine, and using the search set to navigate collections of archived content. A request for user interface data is received from a client device in response to the client device attempting to access a domain. The domain may be parsed to identify a search category corresponding to one of the categories stored in a data store. Subcategories and search collections that are associated with the search category are identified and user interface data may be generated that cause at least a portion of the subcategories and search collections associated with a search component to be rendered in a display of the client device. The search component is configured to use a selected one of the at least a portion of the subcategories to narrow a search conducted using the search component by generating a narrowing search query.

Abstract: The present invention relates to novel compositions and methods for detecting myelitis. The invention also relates to methods of identifying mutations in VPS37a indicative of monophasic acute transverse myelitis.

Abstract: Disclosed are various embodiments for dynamically generating a search set for use in a search application, such as a search engine, and using the search set to navigate collections of archived content. A request for user interface data is received from a client device in response to the client device attempting to access a domain. The domain may be parsed to identify a search category corresponding to one of the categories stored in a data store. Subcategories and search collections that are associated with the search category are identified and user interface data may be generated that cause at least a portion of the subcategories and search collections associated with a search component to be rendered in a display of the client device. The search component is configured to use a selected one of the at least a portion of the subcategories to narrow a search conducted using the search component by generating a narrowing search query.

Abstract: A radiation detector processing assembly is provided including at least one application specific integrated circuit (ASIC). The radiation detector processing assembly includes plural input channels, a common readout, and a readout channel. Each input channel is configured to receive an input corresponding to a detection event from a pixel of a pixelated detector. The common readout is operably coupled to the plural input channels, and is configured to receive a corresponding output signal from each input channel. Each corresponding output signal has a unique address identifying the corresponding input channel. The readout channel is configured to receive a corresponding readout output from the common readout. The readout output includes output signals from a corresponding group of input channels.

Abstract: A radiation detector assembly is provided including a semiconductor detector, pixelated anodes, and at least one processor. The pixelated anodes are disposed on a surface of the semiconductor detector, and configured to generate a primary signal responsive to reception of a photon and a secondary signal responsive to an induced charge caused by reception of a photon by at least one adjacent anode. The at least one processor is operably coupled to the pixelated anodes, and configured to define sub-pixels for each pixelated anode; acquire primary signals and secondary signals from the pixelated anodes; determine sub-pixel locations for acquisition events using the primary and secondary signals; generate a sub-pixel energy spectrum for each sub-pixel; apply at least one energy calibration parameter to adjust the sub-pixel energy spectra for each pixelated anode; and, for each pixelated anode, combine the adjusted sub-pixel energy spectra to provide a pixelated anode spectrum.

Abstract: A radiation detector system is provided including a semiconductor detector, plural pixelated anodes, and at least one processor. The plural pixelated anodes are disposed on a surface of the detector. At least one of the pixelated anodes is configured to generate a collected charge signal corresponding to a charge collected by the pixelated anode and to generate a non-collected charge signal corresponding to a charge collected by an adjacent anode to the pixelated anode. The at least one processor is configured to determine a collected value for the collected charge signal in the pixelated anode; determine a non-collected value for the non-collected charge signal in the pixelated anode corresponding to the charge collected by the adjacent anode; use the non-collected value for the non-collected charge signal to determine a sub-pixel location for the adjacent anode; and use the collected value to count a single event in the pixelated anode.

Abstract: A method for controlling bleeding from bones, comprising the use of copolymers of oxyethylene and oxypropylene or mixtures thereof to cover the bleeding portions of bones. The copolymers are resorbable by the body, not metabolized, simple to prepare, inexpensive, readily available, and do not interfere with the fusion, osteogenesis, and related tissue healing and repair of the affected bones.

Abstract: A radiation detector processing assembly is provided including at least one application specific integrated circuit (ASIC). The radiation detector processing assembly includes plural input channels, a common readout, and a readout channel. Each input channel is configured to receive an input corresponding to a detection event from a pixel of a pixelated detector. The common readout is operably coupled to the plural input channels, and is configured to receive a corresponding output signal from each input channel. Each corresponding output signal has a unique address identifying the corresponding input channel. The readout channel is configured to receive a corresponding readout output from the common readout. The readout output includes output signals from a corresponding group of input channels.

Abstract: The present invention provides pharmaceutical compositions for treating neuromyelitis optica (NMO) comprising a therapeutically effective amount of loop C sequence-containing peptide of aquaporin-4 (AQP4) water channel, or a therapeutically effective fragment or variant thereof. The invention also provides methods for treating NMO by administering therapeutically effective amounts of loop C sequence-containing peptide(s) of AQP4, optionally in an immunosuppressive setting, and also provides diagnostics for detection of NMO in a subject, screening methods for identification of NMO-treating therapeutics and NMO model systems.

Abstract: A radiation detector system is provided including a semiconductor detector, plural pixelated anodes, and at least one processor. The plural pixelated anodes are disposed on a surface of the detector. At least one of the pixelated anodes is configured to generate a collected charge signal corresponding to a charge collected by the pixelated anode and to generate a non-collected charge signal corresponding to a charge collected by an adjacent anode to the pixelated anode. The at least one processor is configured to determine a collected value for the collected charge signal in the pixelated anode; determine a non-collected value for the non-collected charge signal in the pixelated anode corresponding to the charge collected by the adjacent anode; use the non-collected value for the non-collected charge signal to determine a sub-pixel location for the adjacent anode; and use the collected value to count a single event in the pixelated anode.

Abstract: A hockey stick assembly has an elongate rubbery damping material installed within a hollow stick shaft. The insert may be formed with one end that has, or may have a cap or socket mounted at one end that has, an indexing member for locating the elongate material within the hollow shaft. The cap or socket or end may include a widened portion, and may include projections or a peripherally extending flange for engaging the butt end. A cap may be placed over the end of the stick once the insert has been installed. The insert may be removable. It may be a high density rubber or rubber-like polymer that may tend not to rattle. The insert may have constant thickness, and be formed to define a plug and stopper at one end. The other end is trimmed to length and slid into a loose fit within the shaft.

Abstract: A hockey stick assembly has an elongate rubbery damping material installed within a hollow stick shaft. The insert may be formed with one end that has, or may have a cap or socket mounted at one end that has, an indexing member for locating the elongate material within the hollow shaft. The cap or socket or end may include a widened portion, and may include projections or a peripherally extending flange for engaging the butt end. A cap may be placed over the end of the stick once the insert has been installed. The insert may be removable. It may be a high density rubber or rubber-like polymer that may tend not to rattle. The insert may have constant thickness, and be formed to define a plug and stopper at one end. The other end is trimmed to length and slid into a loose fit within the shaft.

Abstract: A radiation detector system is provided including a semiconductor detector, plural pixelated anodes, and at least one processor. At least one of the pixelated anodes is configured to generate a collected charge signal corresponding to charge collected by the pixelated anode and to generate a non-collected charge signal corresponding to charge collected by an adjacent anode. The at least one processor includes a tangible and non-transitory memory having stored thereon instructions configured to direct the at least one processor to determine a collected value for the collected charge signal, to determine a non-collected value for the non-collected charge signal, determine a calibrated value for the non-collected charge signal, determine a total charge produced by a charge sharing event using the collected value and the calibrated value, and count the charge sharing event as a single event if the total charge exceeds a predetermined value.

Abstract: A radiation detector assembly is provided including a semiconductor detector, pixelated anodes, and at least one processor. The pixelated anodes are disposed on a surface of the semiconductor detector, and configured to generate a primary signal responsive to reception of a photon and a secondary signal responsive to an induced charge caused by reception of a photon by at least one adjacent anode. The at least one processor is operably coupled to the pixelated anodes, and configured to define sub-pixels for each pixelated anode; acquire primary signals and secondary signals from the pixelated anodes; determine sub-pixel locations for acquisition events using the primary and secondary signals; generate a sub-pixel energy spectrum for each sub-pixel; apply at least one energy calibration parameter to adjust the sub-pixel energy spectra for each pixelated anode; and, for each pixelated anode, combine the adjusted sub-pixel energy spectra to provide a pixelated anode spectrum.

Abstract: Disclosed are various embodiments for dynamically generating a search set for use in a search application, such as a search engine, and using the search set to navigate collections of archived content. A request for user interface data is received from a client device in response to the client device attempting to access a domain. The domain may be parsed to identify a search category corresponding to one of the categories stored in a data store. Subcategories and search collections that are associated with the search category are identified and user interface data may be generated that cause at least a portion of the subcategories and search collections associated with a search component to be rendered in a display of the client device. The search component is configured to use a selected one of the at least a portion of the subcategories to narrow a search conducted using the search component by generating a narrowing search query.

Abstract: A frame for a cab of a mobile machine includes a primary tube, formed by hydroforming, connected to a secondary tube. The primary tube includes first and second about vertically extending portions and an about horizontally extending portion. The about vertically extending portions are configured to be connected to the mobile machine, and the about horizontally extending portion is disposed between the about vertically extending portions. Dimensions of a cross-section of the primary tube vary along a length of a portion of the primary tube. A secondary tube is connected to the primary tube to another cab frame portion.