Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

Abstract: In its many embodiments, the present invention provides a novel class of imidazo[1,2-a]pyridine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyridine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

Abstract: In its many embodiments, the present invention provides a novel class of imidazo[1,2-a]pyrazine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

Abstract: In its many embodiments, the present invention provides a novel class of imidazo[1,2-a]pyrazine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

Abstract: A corner insert for edge strips used with modified electrodes for electrolytic processes. An electrode that is at least partially submerged in an electrolyte is protected by edge strips to prevent depositions and metallic bridges. The edge strips are typically mitered to abut one another at the corners of the electrode and it is difficult to seal this junction. One solution is to remove the corners of the electrode, provide non-mitered edge strips, and close the gap at the corner with an insert adapted to seal to the additional edges of the electrode created by removing the comers. Another solution is to provide a corner insert having one or more anchors for anchoring the corner insert to the electrode and to respective adjacent edge strips, the corner insert sealing against the edge strips and against opposite sides of the electrode whether or not the corner portion has been removed.

Abstract: A corner insert for edge strips used with modified electrodes for electrolytic processes. An electrode that is at least partially submerged in an electrolyte is protected by edge strips to prevent depositions and metallic bridges. The edge strips are typically mitered to abut one another at the corners of the electrode and it is difficult to seal this junction. One solution is to remove the corners of the electrode, provide non-mitered edge strips, and close the gap at the corner with an insert adapted to seal to the additional edges of the electrode created by removing the corners. Another solution is to provide a corner insert having one or more anchors for anchoring the corner insert to the electrode and to respective adjacent edge strips, the corner insert sealing against the edge strips and against opposite sides of the electrode whether or not the corner portion has been removed.

Abstract: A nonconductive insert is provided to fill the void resulting from the removal of mother-plate corners wrapped within the abutting ends of side and bottom edge strips. The insert includes at least one anchor, adapted to frictionally engage the end of a strip mounted along the edge of the mother plate. The insert and its anchors are designed to completely fill the void left by the missing mother-plate corner, thereby preventing penetration of electrolyte and accumulation of deposits. According to other embodiments of the invention, the insert may be incorporated into the edge-strip end as an integral component of the strip.