Patents by Inventor Michael RAUEN

Michael RAUEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240246056
    Abstract: The present invention relates to a manufacturing device for a pharmaceutical product, a manufacturing module for a pharmaceutical product, a manufacturing system for a pharmaceutical product, a method for producing a pharmaceutical product, a method for producing a DNA template, a method for producing an RNA, a method for producing a formulated RNA and uses of the manufacturing device, module or system. The manufacturing device for a pharmaceutical product comprises a housing, a process chamber, a technical chamber, a separation element, and a control unit. The housing is closed relative to the environment outside the housing. The housing encompasses the process chamber and the technical chamber. The process chamber is separated from the technical chamber by the separation element. The control unit is configured to control a gas flow through the process chamber. The control unit is configured to control the gas flow to provide in the process chamber a positive pressure relative to the environment.
    Type: Application
    Filed: September 1, 2021
    Publication date: July 25, 2024
    Applicants: CureVac RNA Printer GmbH, Tesla Automation GmbH
    Inventors: Benyamin YAZDAN PANAH, Tilmann ROOS, Telmo GRACA, Felix BERTSCH, Veronika FONTIUS, Michael RAUEN, Nico SCHOLTES, Philipp HOFFMANN, Martin KUNZE
  • Publication number: 20210261897
    Abstract: The present invention relates to a bioreactor for RNA in vitro transcription, a method for RNA in vitro transcription, a module for transcribing DNA into RNA and an automated apparatus for RNA manufacturing. Further, the use of a bioreactor for RNA in vitro transcription as described herein is part of the present invention. The present invention relates to an RNA in vitro transcription reactor designed to be operable in an automated manner under GMP-compliant conditions. In particular, said RNA in vitro transcription reactor allows repetitive use of DNA template for various RNA in vitro transcription reactions. Further, the invention relates to an apparatus for RNA manufacturing comprising (a) a module for template DNA synthesis, (b) a module for transcribing DNA into RNA comprising said RNA in vitro transcription reactor, and, optionally, (c) a module for RNA formulation.
    Type: Application
    Filed: June 28, 2019
    Publication date: August 26, 2021
    Applicants: CureVac AG, Tesla Grohmann Automation GmbH
    Inventors: Benyamin YAZDAN PANAH, Tilmann ROOS, Martin KUNZE, Felix BERTSCH, Aniela WOCHNER, Michael RAUEN, Philipp HOFFMANN