Abstract: The present invention relates to a protein binding to GARP in the presence of TGF-? and uses thereof.

Abstract: A refrigerant control system includes: a charge module configured to determine an amount of refrigerant that is present within a refrigeration system of a building; a leak module configured to diagnose that a leak is present in the refrigeration system based on the amount of refrigerant; and at least one module configured to take at least one remedial action in response to the diagnosis that the leak is present in the refrigeration system.

Abstract: A refrigerant control system includes: a charge module configured to determine an amount of refrigerant that is present within a first portion of a refrigeration system within a building; and an isolation module configured to selectively open and close an isolation valve of the refrigeration system and to, via the isolation valve, maintain the amount of refrigerant within the first portion within the building below a predetermined amount of the refrigerant.

Abstract: Described, among other things, are dosage forms for administration to a subject, the dosage forms having at least six ingredients are selected are from the group consisting of clove powder, rutin, hesperidin, baicalin, sulforaphane, moringa leaf extract, rosmarinic acid, guava leaf extract, Panax notoginseng, EGCG, propolis, coriander extract, cardamom extract, cinnamaldehyde, chlorogenic acid, caper fruit, vescalagin, nutmeg extract, and naringenin. The dosage forms can serve as inhibitors of quorum sensing by infectious agents. The described combinations of selected natural products have the ability to inhibit quorum sensing. Quorum sensing is a means by which bacteria and viruses communicate with each other and induce virulence in the body. This combination of natural products is preferably included in nutraceutical formulations in order to promote human immune health.

Abstract: A token sorting apparatus is arranged to supplement a game using gaming tokens, the game having a plurality of stages. The sorting apparatus includes an entry aperture arranged to accept gaming tokens; a sorting mechanism arranged to sort gaming tokens according to a predetermined characteristic of the gaming tokens; a displacement member arranged to urge gaming tokens accepted by the entry aperture to the sorting mechanism; a camera arranged to obtain an image of the sorting mechanism and the displacement member; a display member in digital communication with the camera, the display member arranged to display the image to a user; and a signaling member arranged to provide a signal to the user, the signal being arranged to indicate a stage of the game or a status of the game.

Abstract: The present invention relates to antagonists, particularly antibodies and antigen binding fragments thereof, that bind to the protein galectin-10, particularly human galectin-10. The galectin-10 antagonists disrupt the crystallization of galectin-10 and are therefore useful in methods of preventing and treating diseases and conditions wherein the pathology is linked to the formation/presence of Charcot-Leyden crystals (CLCs).

Abstract: A refrigerant control system includes: a charge module configured to determine an amount of refrigerant that is present within a refrigeration system of a building; a leak module configured to diagnose that a leak is present in the refrigeration system based on the amount of refrigerant; and at least one module configured to take at least one remedial action in response to the diagnosis that the leak is present in the refrigeration system.

Abstract: The present invention relates to antagonists, particularly antibodies and antigen binding fragments thereof, that bind to the protein galectin-10, particularly human galectin-10. The galectin-10 antagonists disrupt the crystallization of galectin-10 and are therefore useful in methods of preventing and treating diseases and conditions wherein the pathology is linked to the formation/presence of Charcot-Leyden crystals (CLCs).

Abstract: A gaming system is provided to maximise the number of betting opportunities in a set period. The gaming system comprises, at least two physical random number generators each having an operative period comprising an available period and an unavailable period; a selecting member arranged to select one physical random number generator during an available period of said physical random number generator and further arranged to deselect said physical random number generator during an unavailable period of said physical random number generator; wherein the gaming system further comprises abetting member arranged to accept betting information from a user for the selected physical random number generator; wherein one physical random number generator is selected at any one time. The aim of the gaming system of the present invention is to provide the maximum number of betting opportunities in a given time period, in order to increase player satisfaction and enhance the overall consumer experience.

Abstract: A refrigeration system includes first and second compressors, a condenser, first and second evaporators, and a valve. The first compressor is fluidly connected to first suction and discharge lines. The second compressor is fluidly connected to second suction and discharge lines. The second suction line is fluidly connected to the first discharge line. The condenser receives refrigerant from the second compressor. The first evaporator receives refrigerant from the condenser and discharges refrigerant to the first suction line. The second evaporator receives refrigerant from the condenser and discharges refrigerant to the second suction line. The valve is disposed between the first evaporator and the first suction line. The first suction line receives refrigerant when the valve is in a first position. The second suction line receives refrigerant when the valve is in a second position. The first compressor is bypassed when the valve is in the second position.

Abstract: A refrigeration system includes first and second compressors, a condenser, first and second evaporators, and a valve. The first compressor is fluidly connected to first suction and discharge lines. The second compressor is fluidly connected to second suction and discharge lines. The second suction line is fluidly connected to the first discharge line. The condenser receives refrigerant from the second compressor. The first evaporator receives refrigerant from the condenser and discharges refrigerant to the first suction line. The second evaporator receives refrigerant from the condenser and discharges refrigerant to the second suction line. The valve is disposed between the first evaporator and the first suction line. The first suction line receives refrigerant when the valve is in a first position. The second suction line receives refrigerant when the valve is in a second position. The first compressor is bypassed when the valve is in the second position.

Abstract: A personal progressive jackpot system is provided, with the aim of improving player satisfaction. The personal progressive jackpot system comprises, an input member arranged to accept identification information unique to a user, and wager information, the wager information having a wager value. The system further comprises a physical random number generator arranged to generate and output a random number during an operative period; a memory arranged to access and store the identification information, the wager information and the random number, the memory further comprising a personal progressive jackpot value associated with the identification information; a controller arranged to modify the personal progressive jackpot value; and a processor.

Abstract: A gaining system is provided to maximise the number of betting opportunities in a set period.

Abstract: A token sorting apparatus is provided, the apparatus arranged to supplement a game using gaming tokens, the game having a plurality of stages, the sorting apparatus comprising: an entry aperture arranged to accept gaining tokens; a sorting mechanism arranged to sort gaming tokens according to a predetermined characteristic of the gaming tokens; a displacement member arranged to urge gaming tokens accepted by the entry aperture to the sorting mechanism; a camera arranged to obtain an image of the sorting mechanism and the displacement member; a display member in digital communication with the camera, the display member arranged to display the image to a user; and a signalling member arranged to provide a signal to the user, the signal being arranged to indicate a stage of the game or a status of the game. The invention aims to provide a readily available prompt to a user of a token sorting apparatus in order to maintain awareness of stages of play of the game and to optimise user performance.

Abstract: A refrigeration system includes first and second compressors, a condenser, first and second evaporators, and a valve. The first compressor is fluidly connected to first suction and discharge lines. The second compressor is fluidly connected to second suction and discharge lines. The second suction line is fluidly connected to the first discharge line. The condenser receives refrigerant from the second compressor. The first evaporator receives refrigerant from the condenser and discharges refrigerant to the first suction line. The second evaporator receives refrigerant from the condenser and discharges refrigerant to the second suction line. The valve is disposed between the first evaporator and the first suction line. The first suction line receives refrigerant when the valve is in a first position. The second suction line receives refrigerant when the valve is in a second position. The first compressor is bypassed when the valve is in the second position.

Abstract: The present disclosure is directed to edible organogel compositions that comprise an organogelator and a flavor component, and processes for preparing the organogel compositions. The organogelator is ethyl cellulose or a combination of ethyl cellulose and an edible wax, preferably candelilla wax, rice bran wax, carnauba wax, paraffin, beeswax, polyethylene wax or combinations thereof. The ethyl cellulose preferably has an average ethoxyl content of from 45.0% to 47.0% by weight of the ethyl cellulose or from 48.0% to 49.5% by weight of the ethyl cellulose. The organogel compositions may be included as the flavor component in confectionery products, such as chewing gums.

Abstract: A refrigerated food container system includes a container defining an inner volume and a thermoelectric module arranged in thermal contact with at least one surface of the container. The thermoelectric module includes a first thermoelectric cooling device and a second thermoelectric cooling device in thermal contact with the first thermoelectric cooling device. A control module is configured to provide a first voltage to the first thermoelectric cooling device and provide a second voltage to the second thermoelectric cooling device.

Abstract: The present invention includes a composition and method of producing aspirin in situ, the method comprising: identifying a subject in need of aspirin or aspirin-like compounds; and providing the subject with a composition comprising: a source of methyl salicylate, an acetyl donor, and L-Arginine, wherein the composition is effective to produce aspirin-triggered resolvins in the subject without the deleterious effect of the aspirin or aspirin-like compounds in the stomach.

Abstract: The present invention relates to antibodies and antigen binding fragments thereof which bind to the cytokine receptor IL-22R, particularly human IL-22R. The invention also relates to pharmaceutical compositions comprising said antibodies or antigen binding fragments thereof, and methods of treating psoriasis, psoriatic arthritis or atopic dermatitis.