Patents by Inventor Michael W. Mueting
Michael W. Mueting has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210129098Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.Type: ApplicationFiled: January 15, 2021Publication date: May 6, 2021Inventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
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Patent number: 10919011Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.Type: GrantFiled: October 19, 2018Date of Patent: February 16, 2021Assignee: Adamis Pharmaceuticals CorporationInventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
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Publication number: 20190054435Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.Type: ApplicationFiled: October 19, 2018Publication date: February 21, 2019Inventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
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Patent number: 10188996Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.Type: GrantFiled: October 2, 2015Date of Patent: January 29, 2019Assignee: Adamis Pharmaceuticals CorporationInventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
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Publication number: 20180235880Abstract: A method of making a dry powder pharmaceutical composition comprising: providing inactive ingredient particles; providing a micronized active ingredient; mixing the inactive ingredient particles with surface-modified nanoparticles to provide an inactive ingredient comprised of particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; and/or mixing the micronized active ingredient with surface-modified nanoparticles to provide a micronized active ingredient comprised of particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; and then mixing the micronized active ingredient with the inactive ingredient; the dry powder compositions made by the method; a method of delivering medicament to the lungs of a mammal by administering a therapeutic amount of the dry powder pharmaceutical composition, and a dry powder inhalation device comprising a mouth piece, a powder containment system, and the dry powder pharmaceutical composition are disclosed.Type: ApplicationFiled: April 24, 2018Publication date: August 23, 2018Inventors: ADAM S. CANTOR, JACQUELINE M. GANSER, MICHAEL W. MUETING, STEPHEN W. STEIN
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Patent number: 9956170Abstract: A method of making a dry powder pharmaceutical composition comprising: providing inactive ingredient particles; providing a micronized active ingredient; mixing the inactive ingredient particles with surface-modified nanoparticles to provide an inactive ingredient comprised of particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; and/or mixing the micronized active ingredient with surface-modified nanoparticles to provide a micronized active ingredient comprised of particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; and then mixing the micronized active ingredient with the inactive ingredient; the dry powder compositions made by the method; a use of said composition for the manufacture of a medicament for being delivered to the lungs of a mammal by administering a therapeutic amount of the dry powder pharmaceutical composition, and a dry powder inhalation device comprising a mouth piece, a powder containment system, and the dry poType: GrantFiled: June 22, 2009Date of Patent: May 1, 2018Assignee: 3M Innovative Properties CompanyInventors: Adam S. Cantor, Jacqueline M. Ganser, Michael W. Mueting, Stephen W. Stein
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Patent number: 9861580Abstract: A method of making active pharmaceutical ingredient particles with surface-modified nanoparticles deposited on the particles' surfaces, the method comprising: providing a plurality of media particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; mixing the plurality of media particles with the active ingredient particles, both of which are in dry form, to provide active ingredient particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; and separating the plurality of media particles from the active ingredient particles having surfaces with the surface-modified nanoparticles deposited on the surfaces is disclosed.Type: GrantFiled: June 22, 2009Date of Patent: January 9, 2018Assignee: 3M Innovative Properties CompanyInventors: Michael W. Mueting, Daniel C. Duan, Stephen W. Stein
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Publication number: 20170095782Abstract: Disclosed herein are powder mixing apparatuses and methods that utilize the deagglomerizing and mixing effects of an air flow that impacts a flowing powder. The resulting powder can have smaller particle sizes and/or exhibit a more homogenous mixture than the premixed powder.Type: ApplicationFiled: October 2, 2015Publication date: April 6, 2017Inventors: Stephen W. Stein, Michael W. Mueting, Herbert C. Chiou, James S. Stefely
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Patent number: 9072664Abstract: Powder drug compositions exhibiting improved flow properties are manufactured by spraying a suspension of surface-modified nanoparticles having an average particle size diameter of less than 100 nm in a dryable liquid carrier onto particles of a powder ingredient of a drug composition. The liquid carrier is rapidly dried so as to leave the nanoparticles on the powder. Other ingredients of the powder drug composition can also be added.Type: GrantFiled: April 17, 2009Date of Patent: July 7, 2015Assignee: 3M INNOVATIVE PROPERTIES COMPANYInventors: Stephen W. Stein, Michael W. Mueting, Timothy D. Dunbar
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Publication number: 20110104362Abstract: A method of making active pharmaceutical ingredient particles with surface-modified nanoparticles deposited on the particles' surfaces, the method comprising: providing a plurality of media particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; mixing the plurality of media particles with the active ingredient particles, both of which are in dry form, to provide active ingredient particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; and separating the plurality of media particles from the active ingredient particles having surfaces with the surface-modified nanoparticles deposited on the surfaces is disclosed.Type: ApplicationFiled: June 22, 2009Publication date: May 5, 2011Inventors: Michael W. Mueting, Daniel C. Duan, Stephen W. Stein
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Publication number: 20110076336Abstract: A method of making a dry powder pharmaceutical composition comprising: providing inactive ingredient particles; providing a micronized active ingredient; mixing the inactive ingredient particles with surface-modified nanoparticles to provide an inactive ingredient comprised of particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; and/or mixing the micronized active ingredient with surface-modified nanoparticles to provide a micronized active ingredient comprised of particles having surfaces with the surface-modified nanoparticles deposited on the surfaces; and then mixing the micronized active ingredient with the inactive ingredient; the dry powder compositions made by the method; a use of said composition for the manufacture of a medicament for being delivered to the lungs of a mammal by administering a therapeutic amount of the dry powder pharmaceutical composition, and a dry powder inhalation device comprising a mouth piece, a powder containment system, and the dry poType: ApplicationFiled: June 22, 2009Publication date: March 31, 2011Inventors: Adam S. Cantor, Jacqueline M. Ganser, Michael W. Mueting, Stephen W. Stein
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Publication number: 20110064867Abstract: Powder drug compositions exhibiting improved flow properties are manufactured by spraying a suspension of surface-modified nanoparticles having an average particle size diameter of less than 100 nm in a dryable liquid carrier onto particles of a powder ingredient of a drug composition. The liquid carrier is rapidly dried so as to leave the nanoparticles on the powder. Other ingredients of the powder drug composition can also be added.Type: ApplicationFiled: April 17, 2009Publication date: March 17, 2011Inventors: Stephen W. Stein, Michael W. Mueting, Timothy D. Dunbar
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Patent number: 7659725Abstract: A method of assessing the suitability of a metered dose inhaler actuator A test canister equipped with a valve and containing a pressurized propellant is provided. One or more actuators manufactured for use in a metered dose inhaler is provided and tested, wherein each actuator is tested by coupling the canister to the actuator, positioning the actuator with respect to an electrostatic measurement device and firing the canister such that electrostatic charge from an aerosol emitted by the canister is measured by the electrostatic measurement device. The measured electrostatic charge is compared to a predetermined specification range to make a determination whether the measured electrostatic charge is within or outside the predetermined specification range and accordingly whether the actuator is or is not acceptable.Type: GrantFiled: March 22, 2007Date of Patent: February 9, 2010Assignee: 3M Innovative Properties CompanyInventors: Michael W. Mueting, Stephen W. Stein
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Publication number: 20090121722Abstract: A method of assessing the suitability of a metered dose inhaler actuator A test canister equipped with a valve and containing a pressurized propellant is provided. One or more actuators manufactured for use in a metered dose inhaler is provided and tested, wherein each actuator is tested by coupling the canister to the actuator, positioning the actuator with respect to an electrostatic measurement device and firing the canister such that electrostatic charge from an aerosol emitted by the canister is measured by the electrostatic measurement device. The measured electrostatic charge is compared to a predetermined specification range to make a determination whether the measured electrostatic charge is within or outside the predetermined specification range and accordingly whether the actuator is or is not acceptable.Type: ApplicationFiled: March 22, 2007Publication date: May 14, 2009Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Michael W. Mueting, Stephen W. Stein