Patents by Inventor Michael Ybarra Lucero

Michael Ybarra Lucero has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240018589
    Abstract: The present disclosure relates to materials and methods for spatially analyzing nucleic acids that have been fragmented with a transposase enzyme, alone or in combination with other types of analytes.
    Type: Application
    Filed: July 6, 2023
    Publication date: January 18, 2024
    Inventors: Michael Schnall-Levin, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Patrik Stahl, Jonas Frisen, Maja Marklund, Enric Llorens Bobadilla
  • Publication number: 20230340596
    Abstract: The present disclosure relates to materials and methods for spatially analyzing nucleic acids that have been fragmented with a transposase enzyme, alone or in combination with other types of analytes.
    Type: Application
    Filed: September 19, 2022
    Publication date: October 26, 2023
    Inventors: Michael Schnall-Levin, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Patrik Stahl, Jonas Frisen, Maja Marklund, Enric Llorens Bobadilla
  • Publication number: 20230323447
    Abstract: The present disclosure relates to materials and methods for spatially analyzing nucleic acids that have been fragmented with a transposase enzyme, alone or in combination with other types of analytes
    Type: Application
    Filed: August 27, 2019
    Publication date: October 12, 2023
    Applicant: 10x Genomics, Inc.
    Inventors: Michael Schnall-Levin, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Patrik Stahl, Jonas Frisen, Maja Marklund, Enric Llorens Bobadilla, Eswar Prasad Ramachandran Iyer, Lucas Frenz, Augusto Manuel Tentori, Rajiv Bharadwaj
  • Publication number: 20230203577
    Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
    Type: Application
    Filed: August 24, 2022
    Publication date: June 29, 2023
    Inventors: Phillip Belgrader, Zachary Bent, Rajiv Bharadwaj, Vijay Kumar Sreenivasa Gopalan, Josephine Harada, Christopher Hindson, Mohammad Rahimi Lenji, Michael Ybarra Lucero, Geoffrey McDermott, Elliott Meer, Tarjei Sigurd Mikkelsen, Christopher Joachim O'Keeffe, Katherine Pfeiffer, Andrew D. Price, Paul Ryvkin, Serge Saxonov, John R. Stuelpnagel, Jessica Michele Terry, Tobias Daniel Wheeler, Indira Wu, Solongo Batjargal Ziraldo, Stephane Claude Boutet, Sarah Taylor, Niranjan Srinivas
  • Patent number: 11519033
    Abstract: The present disclosure relates to materials and methods for spatially analyzing nucleic acids that have been fragmented with a transposase enzyme, alone or in combination with other types of analytes.
    Type: Grant
    Filed: March 7, 2022
    Date of Patent: December 6, 2022
    Assignee: 10x Genomics, Inc.
    Inventors: Michael Schnall-Levin, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Patrik Stahl, Jonas Frisen, Maja Marklund, Enric Llorens Bobadilla
  • Publication number: 20220333195
    Abstract: The present disclosure relates to materials and methods for spatially analyzing nucleic acids that have been fragmented with a transposase enzyme, alone or in combination with other types of analytes.
    Type: Application
    Filed: March 7, 2022
    Publication date: October 20, 2022
    Applicant: 10x Genomics, Inc.
    Inventors: Michael Schnall-Levin, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Patrik Stahl, Jonas Frisen, Maja Marklund, Enric Llorens Bobadilla
  • Publication number: 20220228220
    Abstract: The present disclosure provides methods, systems, and compositions for parallel processing of nucleic acid samples. Methods and systems of the present disclosure comprise the use of sample-specific barcode sequences, which facilitate the multiplexing of samples, detection of discrete cell populations within a pooled population, and detection of partitions comprising more than one cell.
    Type: Application
    Filed: August 31, 2021
    Publication date: July 21, 2022
    Inventors: Stephane Claude Boutet, Michael Ybarra Lucero, Elliott Meer, Tarjei Sigurd Mikkelsen, Katherine Pfeiffer, Sarah Taylor, Niranjan Srinivas
  • Publication number: 20220106641
    Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
    Type: Application
    Filed: September 13, 2021
    Publication date: April 7, 2022
    Inventors: Phillip BELGRADER, Zachary BENT, Rajiv BHARADWAJ, Vijay Kumar Sreenivasa GOPALAN, Josephine HARADA, Christopher HINDSON, Mohammad Rahimi LENJI, Michael Ybarra LUCERO, Geoffrey McDERMOTT, Elliott MEER, Tarjei Sigurd MIKKELSEN, Christopher Joachim O'KEEFFE, Katherine PFEIFFER, Andrew D. PRICE, Paul RYVKIN, Serge SAXONOV, John R. STUELPNAGEL, Jessica Michele TERRY, Tobias Daniel WHEELER, Indira WU, Solongo Batjargal ZIRALDO, Stephane Claude BOUTET, Sarah TAYLOR, Niranjan SRINIVAS
  • Patent number: 11180805
    Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: November 23, 2021
    Assignee: 10X GENOMICS, INC
    Inventors: Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Katherine Pfeiffer, Stephane Claude Boutet
  • Publication number: 20210324457
    Abstract: This disclosure relates to methods for generating spatially barcoded arrays using concentration gradients.
    Type: Application
    Filed: August 27, 2019
    Publication date: October 21, 2021
    Inventors: Eswar Prasad Ramachandran Iyer, Michael Schnall-Levin, Augusto Manuel Tentori, Tarjei Sigurd Mikkelsen, Benjamin Hindson, Michael Ybarra Lucero, Rajiv Bharadwaj, Yifeng Yin, Zachary Bent, Jennifer Chew, Meghan L. F. Frey, Linda Kvastad, Joakim Lundeberg, Eva Gracia Villacampa
  • Publication number: 20210317524
    Abstract: Methods for determining a location of a feature in a spatial array of features include: providing a spatial array including a plurality of features on a substrate, where a feature of the plurality of features has a capture probe, and where the capture probe has a spatial barcode and a constant sequence; hybridizing a first sequencing probe to the spatial barcode, where the first sequencing probe has a first label and a first nucleotide sequence; obtaining a first image of the first label with the first sequencing probe hybridized to the spatial barcode; determining, based on the first image, a first portion of a sequence of the spatial barcode; and associating the feature with a location in the spatial array based on a location of the first label in the first image.
    Type: Application
    Filed: August 27, 2019
    Publication date: October 14, 2021
    Inventors: Michael Ybarra Lucero, Michael Schnall-Levin, Tarjei Sigurd Mikkelsen, Eswar Prasad Ramachandran Iyer, Paul Giresi, Benjamin Hindson
  • Publication number: 20210140969
    Abstract: The present disclosure provides methods, systems, and compositions for parallel processing of nucleic acid samples. Methods and systems of the present disclosure comprise the use of sample-specific barcode sequences, which facilitate the multiplexing of samples, detection of discrete cell populations within a pooled population, and detection of partitions comprising more than one cell.
    Type: Application
    Filed: June 5, 2020
    Publication date: May 13, 2021
    Inventors: Stephane Claude Boutet, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Katherine Pfeiffer
  • Publication number: 20210130892
    Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
    Type: Application
    Filed: October 29, 2020
    Publication date: May 6, 2021
    Inventors: Phillip Belgrader, Zachary Bent, Rajiv Bharadwaj, Vijay Kumar Sreenivasa Gopalan, Josephine Harada, Christopher Hindson, Mohammad Rahimi Lenji, Michael Ybarra Lucero, Geoffrey McDermott, Elliott Meer, Tarjei Sigurd Mikkelsen, Christopher Joachim O'Keeffe, Katherine Pfeiffer, Andrew D. Price, Paul Ryvkin, Serge Saxonov, John R. Stuelpnagel, Jessica Michele Terry, Tobias Daniel Wheeler, Indira Wu, Solongo Batjargal Ziraldo, Stephane Claude Boutet, Sarah Taylor, Niranjan Srinivas
  • Publication number: 20210010070
    Abstract: The present disclosure relates to materials and methods for spatially analyzing nucleic acids that have been fragmented with a transposase enzyme, alone or in combination with other types of analytes.
    Type: Application
    Filed: May 18, 2020
    Publication date: January 14, 2021
    Inventors: Michael Schnall-Levin, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Patrik Stahl, Jonas Frisen, Maja Marklund, Enric Llorens
  • Publication number: 20200407781
    Abstract: The present disclosure relates to materials and methods for spatially analyzing nucleic acids that have been fragmented with a transposase enzyme, alone or in combination with other types of analytes.
    Type: Application
    Filed: May 18, 2020
    Publication date: December 31, 2020
    Inventors: Michael Schnall-Levin, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Patrik Stahl, Jonas Frisen, Maja Marklund, Enric Llorens
  • Patent number: 10858702
    Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
    Type: Grant
    Filed: June 17, 2019
    Date of Patent: December 8, 2020
    Assignee: 10X GENOMICS, INC.
    Inventors: Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Katherine Pfeiffer, Stephane Claude Boutet
  • Patent number: 10815525
    Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
    Type: Grant
    Filed: June 12, 2019
    Date of Patent: October 27, 2020
    Assignee: 10X GENOMICS, INC.
    Inventors: Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Katherine Pfeiffer, Stephane Claude Boutet
  • Publication number: 20200291481
    Abstract: The present disclosure provides methods, systems, and compositions for parallel processing of nucleic acid samples. Methods and systems of the present disclosure comprise the use of sample-specific barcode sequences, which facilitate the multiplexing of samples, detection of discrete cell populations within a pooled population, and detection of partitions comprising more than one cell.
    Type: Application
    Filed: October 10, 2019
    Publication date: September 17, 2020
    Inventors: Stephane Claude Boutet, Michael Ybarra Lucero, Tarjei Sigurd Mikkelsen, Katherine Pfeiffer
  • Publication number: 20200140944
    Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
    Type: Application
    Filed: November 22, 2019
    Publication date: May 7, 2020
    Inventors: Phillip Belgrader, Zachary Bent, Rajiv Bharadwaj, Vijay Kumar Sreenivasa Gopalan, Josephine Harada, Christopher Hindson, Mohamad Rahimi Lenji, Michael Ybarra Lucero, Geoffrey McDermott, Elliott Meer, Tarjei Sigurd Mikkelsen, Christopher Joachim O'Keeffe, Katherine Pfeiffer, Andrew D. Price, Paul Ryvkin, Serge Saxonov, John R. Stuelpnagel, Jessica Michele Terry, Tobias Daniel Wheeler, Indira Wu, Solongo Batjargal Ziraldo
  • Publication number: 20200002763
    Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing and analyte characterization. Such polynucleotide processing may be useful for a variety of applications, including analyte characterization by polynucleotide sequencing. The compositions, methods, systems, and devices disclosed herein generally describe barcoded oligonucleotides, which can be bound to a bead, such as a gel bead, useful for characterizing one or more analytes including, for example, protein (e.g., cell surface or intracellular proteins), genomic DNA, and RNA (e.g., mRNA or CRISPR guide RNAs). Also described herein, are barcoded labelling agents and oligonucleotide molecules useful for “tagging” analytes for characterization.
    Type: Application
    Filed: June 12, 2019
    Publication date: January 2, 2020
    Inventors: Phillip Belgrader, Zachary Bent, Rajiv Bharadwaj, Vijay Kumar Sreenivasa Gopalan, Josephine Harada, Christopher Hindson, Mohammad Rahimi Lenji, Michael Ybarra Lucero, Geoffrey McDermott, Elliott Meer, Tarjei Sigurd Mikkelsen, Christopher Joachim O'Keeffe, Katherine Pfeiffer, Andrew D. Price, Paul Ryvkin, Serge Saxonov, John R. Stuelpnagel, Jessica Michele Terry, Tobias Daniel Wheeler, Indira Wu, Solongo Batjargal Ziraldo, Stephane Claude Boutet, Sarah Taylor, Niranjan Srinivas