Patents by Inventor Michel Langlois

Michel Langlois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4657911
    Abstract: New derivatives of 3-amino quinuclidine of formula: ##STR1## in which X=sulfur or oxygen; R=H, lower alkyl or benzyl; and Ar=substituted phenyl or substituted pyrimidinyl.These new derivatives have utility in therapeutics as accelerators of the gastro-intestinal motor function and as medicament potentiators.
    Type: Grant
    Filed: June 29, 1983
    Date of Patent: April 14, 1987
    Assignee: Delalande S.A.
    Inventors: Thierry F. Imbert, Nicole A. M. Dorme, Michel Langlois
  • Patent number: 4598084
    Abstract: N-arylated oxazolidine-2-one derivatives corresponding to the formula: ##STR1## and of S(+) configuration, A representing in this case the hydroxyl radical or of R (+) configuration, A designating then the N-methylamino group, as well as the acid addition salts thereof.Application in therapeutics more particularly as monoamine oxidase inhibitors.
    Type: Grant
    Filed: June 3, 1983
    Date of Patent: July 1, 1986
    Assignee: Delalande S.A.
    Inventors: Margherita Strolin-Benedetti, Patrick G. Guerret, Michel Langlois, Philippe L. Dostert
  • Patent number: 4528380
    Abstract: New tetrazole derivatives, characterized in that they correspond to the formula: ##STR1## in which R.sub.1 represents: either a hydrogen atom in any one of the positions 1 to 5 of the tetrazole nucleus, R designating a branched alkyl group comprising at least 5 carbon atoms or a branched alkenyl group, or a methyl group in position 2(3) of the tetrazole nucleus, R representing the (1-propyl)n butyl chain.These new derivatives are useful as medicaments, more especially for their anti-epileptic action.
    Type: Grant
    Filed: December 6, 1982
    Date of Patent: July 9, 1985
    Assignee: Delalande S.A.
    Inventors: Alain P. Lacour, Michel Langlois, Maurice F. Jalfre, Bernard P. Bucher
  • Patent number: 4526786
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: July 2, 1985
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Phillippe L. Dostert
  • Patent number: 4517197
    Abstract: A compound of the formula ##STR1## where R is selected from the group consisting of CH.sub.3 --CO--(CH.sub.2).sub.2 --O--, ##STR2## The compounds are useful in treating depression.
    Type: Grant
    Filed: July 29, 1983
    Date of Patent: May 14, 1985
    Assignee: Delalande S.A.
    Inventors: Jean-Francois R. Ancher, Guy R. Bourgery, Philippe L. Dostert, Colette A. Douzon, Patrick G. Guerret, Alain P. Lacour, Michel Langlois
  • Patent number: 4486349
    Abstract: Process for preparing a para-quinone or ortho-quinone derivative, possibly alkoxylated or aryloxylated, which consists in oxidizing respectively the corresponding hydroquinone or pyrocatechic derivative, by means of the complex prepared, in situ or separately, by combining a cuprous salt, a hydrocarbon substituted by a cyano group and molecular oxygen, the oxidation being possibly carried out in the presence of an alkoxylating or aryloxylating agent of the hydroxylated derivative type.
    Type: Grant
    Filed: November 12, 1982
    Date of Patent: December 4, 1984
    Assignee: Delalande, S.A.
    Inventors: Michel Maumy, Patrice J. G. Capdevielle, Philippe L. Dostert, Michel Langlois
  • Patent number: 4476136
    Abstract: Derivatives corresponding to the general formula: ##STR1## in which Ar represents a phenyl group; a phenyl group substituted by a halogen atom or by a trifluoromethyl group; or the (chloro-3 fluoro-4) phenyl group and n is either equal to zero or equal to 1 in which case X is a chain chosen from the following: --CH.sub.2 --CH.sub.2 --, --CH.dbd.CH--, --C.tbd.C--, --CH.sub.2 --O-- whose CH.sub.2 group is linked to Ar.These compounds are useful as medicaments more especially for the treatment of troubles of the central nervous system and senescence.
    Type: Grant
    Filed: February 24, 1982
    Date of Patent: October 9, 1984
    Assignee: Delalande S.A.
    Inventors: Philippe L. Dostert, Alain P. Lacour, Michel Langlois, Margherita Strolin-Benedetti
  • Patent number: 4470993
    Abstract: Method of treating the central nervous system troubles such as the Parkinson's disease and the senescence troubles, generally treated by the B type monoamine oxidase inhibitors, which comprises administering internally to a human being requiring such treatment a therapeutically effective amount of N-aryl 5-aminomethyl oxazolidine-2-one derivatives.
    Type: Grant
    Filed: March 3, 1983
    Date of Patent: September 11, 1984
    Assignee: Delalande S.A.
    Inventors: Jean-Francois R. Ancher, Guy R. Bourgery, Philippe L. Dostert, Colette A. Douzon, Patrick G. Guerret, Alain P. Lacour, Michel Langlois, Margherita Strolin-Benedetti
  • Patent number: 4459296
    Abstract: There are disclosed piperidinio, piperazino and homopiperazino derivatives wherein there is N-substitution by a heterocyclic compound taken from the group benzimidazole, indole, purine or benzotriazole and to the organic or mineral acid addition salts of these derivatives. The process for preparation of such compounds and their use is also disclosed.
    Type: Grant
    Filed: April 20, 1982
    Date of Patent: July 10, 1984
    Assignee: Delalande S.A.
    Inventors: Jean-Francois R. Ancher, Patrick G. Guerret, Michel Langlois, Jacky A. Tisne-Versailles
  • Patent number: 4435415
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: March 6, 1984
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Philippe L. Dostert
  • Patent number: 4413001
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: June 16, 1982
    Date of Patent: November 1, 1983
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Philippe L. Dostert
  • Patent number: 4395416
    Abstract: Derivatives of formula: ##STR1## in which Z< represents: either an amino group of struture >N-R.sub.1 where R.sub.1 represents a linear or branched alkyl group with 1 to 5 carbon atoms or a phenyl group possibly substituted by a chlorine atom, in which case:n=1 or 2,the pair (A, C X) assumes the following values: (S, C.dbd.O), (S, CH.sub.2), (O, CH.sub.2), (O, CH--C.sub.6 H.sub.5), andR represents a hydrogen or halogen atom, one or more methoxy groups or the butadiene-1,3 ylene chain ##STR2## fixed in position 5,6 of the phenyhl nucleus and thus forming with this latter a naphthyl nucleus;or a methylene group (--CH.sub.2 --), in which case:n=1 or 2,A represents the oxygen atom,>C X represents a carbonyl group (>C.dbd.O) or thiocarbonyl group (>C.dbd.S), andR has the same meanings as previously,as well as the mineral or organic acid addition salts thereof. The compounds exhibit anti-convulsion and analgesic activity.
    Type: Grant
    Filed: January 21, 1982
    Date of Patent: July 26, 1983
    Assignee: Delalande S.A.
    Inventors: Michel Langlois, Bernard P. Bucher, Philippe L. Dostert, Alain P. Lacour, Gerard H. Moinet
  • Patent number: 4372967
    Abstract: Derivatives of 5H-furanone-2 and 3H-dihydrofuranone-2, substituted at the 3 position with substituted phenyl and at the 5 position with substituted methyl, are prepared by various processes. The derivatives are inhibitors of monoamine oxidase and are useful for treating depression.
    Type: Grant
    Filed: February 26, 1982
    Date of Patent: February 8, 1983
    Assignee: Delalande S.A.
    Inventors: Michel Langlois, Alain P. Lacour, Bernard P. Bucher, Gisele C. Mocquet
  • Patent number: 4348393
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: June 4, 1979
    Date of Patent: September 7, 1982
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Phillippe L. Dostert
  • Patent number: 4346102
    Abstract: Derivatives of 5H-furanone-2 and 3H-dihydrofuranone-2, substituted at the 3 position with substituted phenyl and at the 5 position with substituted methyl, are prepared by various processes. The derivatives are inhibitors of monoamine oxidase and are useful for treating depression.
    Type: Grant
    Filed: April 28, 1980
    Date of Patent: August 24, 1982
    Assignee: Delalande S.A.
    Inventors: Michel Langlois, Alain P. Lacour, Bernard P. Bucher, Gisele C. Mocquet
  • Patent number: 4287351
    Abstract: N-aryl oxazolidinones, oxazolidinethiones, pyrrolidinones, pyrrolidines and thiazolidinones are disclosed. These compounds possess antidepressant activity.
    Type: Grant
    Filed: February 6, 1980
    Date of Patent: September 1, 1981
    Assignee: Delalande S.A.
    Inventors: Guy R. Bourgery, Colette A. Douzon, Jean-Francois R. Ancher, Alain P. Lacour, Patrick G. Guerret, Michel Langlois, Phillippe L. Dostert