Abstract: Bicyclic imino acids, particularly 2-carboxylic acid derivatives of azabicycloalkanes and process for preparing them.These compounds have therapeutical activity and may be used as medicines, particularly as cardiovascular and antihypertensive drugs in human or veterinary medicine.

Abstract: Compounds of the formula ##STR1## in which A represents a vinylene or dimethylene radical, q is 0 or 1, R is an alkyl radical which can carry an amino group, X represents --S-- or --NH--, and R.sub.1 is a hydrogen atom or a radical of formula ##STR2## in which R.sub.2 is a hydroxy or alkoxy and R.sub.3 is a hydrogen atom or an alkyl, cycloalkylalkyl or phenylalkyl radical each having no more than a total of 8 carbon atoms, or an unsubstituted or substituted alkylthioalkyl radical.These compounds are useful as medicaments, especially anti-hypertensive medicaments.

Abstract: This invention relates to trifluorethylamines and to a process for producing the same.These trifluorethylamines are substituted on the nitrogen atom with a lower alkyl or a cyclo lower alkyl radical.They are endowed with interesting pharmacological properties.

Abstract: Certain phenyl amines have been prepared wherein the "methyl" carbon is substituted with a polyfluoroalkyl radical. The compounds form acid addition salts, exist in resolvable stereoisomeric forms, and are useful for treating hypertension. Formulations for human and veterinary medicine are described, as well as methods of use.

Abstract: This invention relates to novel substituted aryl lower alkamine and more precisely to arylmethylamine, the methyl group of which is substituted with one more polyfluoromethyl radicals.This invention also relates to the process for producing said compounds.The resulting compounds have pharmacological utility and may be used as a drug in human and veterinary medicine.

Abstract: This invention relates to omega-mercaptopropionylamides, the nitrogen atom of which is included as a ring atom of a cyclic amino acid.The application also discloses a process for producing said compounds which comprises reacting an omega-mercaptopropionic acid, or a functional derivative thereof, with a cyclic amino acid.This invention further relates to pharmaceutical compositions incorporating such an omega-mercaptopropionylamide as active ingredient together with a pharmaceutically-acceptable carrier or vehicle, and a method of employing said compounds.They find a use in human therapy, namely, as antihypertensive agents.

Abstract: Certain arylmethyl amines have been prepared wherein the "methyl" carbon is substituted with a polyfluoroalkyl radical. The compounds form acid addition salts, exist in resolvable stereoisomeric forms, and are useful for treating hypertension. Formulations for human and veterinary medicine are described, as well as methods of use.

Abstract: Disubstituted piperazines of the formula ##STR1## in which n is 1 or 2,m is 0 or 1, andHet is pyridyl, pyrimidinyl, pyrazinyl, thiazolyl or thiadiazolyl each optionally substituted by one or more alkyl having from 1 to 5 carbon atoms inclusive.These compounds and their physiologically tolerable acid addition salts thereof may be used as medicines especially in the treatment of hypertension.

Abstract: Disubstituted piperazines of the formula: ##STR1## in which: n is 1 or 2,X is oxygen and Y is sulfur or sulfonyl or X and Y are both sulfur or sulfonyl, andHet is a 5- or 6-membered heterocyclic radical having from 1 to 3 hetero atoms inclusive selected from nitrogen and sulfur and optionally substituted by one or more alkyl each having from 1 to 5 carbon atoms inclusive.These compounds may be used as medicines, especially in the treatment of central nervous system disorders and Parkinson's disease.

Abstract: This invention relates to 4-aminopiperidines and more precisely to 4-aminopiperidines the nitrogen atom of the piperidine ring is substituted with an aryl lower alkyl side-chain.This invention also relates to processes for producing the same.This invention further extends to pharmaceutical compositions and to the method of using the same.

Abstract: Disubstituted piperazines of the formula: ##STR1## wherein: ##STR2## is naphthyl, benzo [b] furanyl, benzo [b] thienyl, benzodioxolyl, benzodioxanyl, benzodioxacycloheptanyl, coumaranyl, chromanyl, .DELTA..sup.3 -chromenyl, thiochromanyl or .DELTA..sup.3 -thiochromenyl,X is nitrogen and simultaneously Y is oxygen or sulfur, orX is sulfur, imino (NH) or methylimino (N CH.sub.3) and simultaneously Y is nitrogen, andR is hydrogen, lower alkyl, phenyl, halophenyl, lower-alkylphenyl or lower alkoxyphenyl.These compounds possess interesting pharmacological and therapeutic properties, and may be used as medicines, especially in the treatment of hypertension, peripheral vascular disorders and Parkinson's disease.

Abstract: This invention relates to novel quinazolinones, the nitrogen of which is bound to 4-amino piperidinyl-1 structures.This invention also relates to processes for producing these compounds.They have interesting pharmacological properties which make them useful in human or veterinary medicine for treating hypertension.

Abstract: This invention relates to novel acetamides, the nitrogen of which is substituted with an amino lower alkyl chain.This invention also relates to a process for producing the said N-substituted acetamides.The end compounds have therapeutical utility and find a use as anti-convulsant agents.

Abstract: Cyclopropylmethylamines which are substituted on the 2-position of nitrogen heterocycles so as to provide new compounds of the formula ##STR1## wherein A is oxygen, sulfur, or nitrogen; the other "R" variables in general are hydrogen, lower-alkyl, cyclopropyl, or lower-alkyl substituted cyclopropyl; and the n's are the numbers 0 to 3, inclusive, and acid addition salts thereof, are disclosed. The compounds are cardiovascular agents, which are depressive of the central nervous system. Their effects include hypnosis, analgesia, and neuro-modulation. They can be used as anti-hypertensive agents.

Abstract: Heterocyclic compounds of the formula: ##STR1## WHEREIN ONE OF Y and Z is CH, the other being N, A is a straight or branched saturated hydrocarbon chain from C.sub.2 to C.sub.6 inclusive, X is chlorine, hydroxy, alkoxy or alkylthio each from C.sub.1 to C.sub.5 inclusive, R is hydrogen, alkyl, hydroxyalkyl or dihydroxyalkyl each from C.sub.1 to C.sub.3 inclusive, R' is halogen, alkyl or alkoxy each from C.sub.1 to C.sub.3 inclusive and n is 0, 1 or 2.These compounds, their optical isomers and their physiologically tolerable salts are used as medicines especially in the treatment of central nervous system disorders.

Abstract: This invention relates to propanol derivatives and to a process for their preparation.

Abstract: (3-amino-2-hydroxy propyloxy) thiochromans of the formula ##STR1## wherein A is hydrogen or halogen, R.sub.1 is hydrogen or lower alkyl, and R.sub.2 is lower alkyl or cyclo lower alkyl.These compounds possess cardiovascular properties and may be used as blockers of cardiac .beta. adrenergic receptors.

Abstract: This invention relates to amino piperidines bearing on the endocyclic nitrogen atom an aryloxy alkyl side chain and the acid addition salts thereof. This invention also relates to processes for making the same.The compounds of this invention have therapeutical utility namely in the cardiovascular field. They may be used in the form of pharmaceutical compositions.DESCRIPTION OF THE PRIOR ARTThe prior art may be illustrated with the following referencesFrench drug Patents Nos. 2429 M; 2430 M; 2431 M;Belgian Patent No. 615,350.SUMMARY OF THE INVENTIONThis invention relates to new 4-amino piperidines and more particularly to N-aralkoxy 4-phenylamino piperidines. The aryl and phenyl nuclei may be unsubstituted or substituted by one or several substituents.This invention also provides processes for producing such compounds. Namely they may be produced by condensing an aryloxy alkyl halide with a 4-phenylamino piperidine.

Abstract: Benzodioxole compounds of the formula: vasodilator ##STR1## WHEREIN R.sub.1 is hydrogen, lower alkyl, aryl, haloaryl, lower-alkylaryl, lower-alkoxyaryl, methylenedioxyaryl, ethylenedioxyaryl, trifluoromethylaryl, nitroaryl or aminoaryl,R.sub.2 is lower-alkyl, aryl, haloaryl, lower-alkylaryl, lower-alkoxyaryl, methylenedioxyaryl, ethylenedioxyaryl, trifluoromethylaryl, nitroaryl or aminoaryl, orR.sub.1 + r.sub.2 are --(CH.sub.2).sub.4 --, --(CH.sub.2).sub.5 -- or --(CH.sub.2).sub.6 -- andHet is pyridyl, pyrimidinyl, pyridazinyl, pyrazinyl, quinazolinyl, 1,3,5 triazinyl or 1,3-thiazolyl, each being optionally substituted by lower-alkyl, lower-alkoxy, hydroxyl or phenyl.These compounds are used as medicines especially as peripheral vasocilator agent and central nervous system stimulant.

Abstract: The present invention relates to cyclopropylmethyl amines substituted by a heterocyclic radical.More particularly the heterocyclic radical is a nitrogen containing ring with 5, 6 or 7 links interrupted by another hetero atom selected from the group consisting of oxygen, sulphur and imino--NH--The invention also relates to the acid addition salts thereof with physiologically compatible mineral or organic acids.The invention extends to the processes for making them and the intermediates produced hereto.The invention also includes the pharmaceutical compositions incorporating as active ingredient at least one compound of the invention with an inert carrier.The compounds have therapeutic utility namely on the cardio-vascular diseases and on the neuro-psychological disturbances.