Patents by Inventor Michele Aguera

Michele Aguera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL HUMAN ULIP/CRMP PROTEIN AND USE THEREOF IN DIAGNOSIS AND TREATMENT OF CANCERS AND PARANEOPLASTIC NEUROLOGICAL SYNDROMES
    Publication number: 20190119339
    Abstract: A purified polypeptide, designated ULIP6, comprising the amino acid sequence SED ID No. 2 or an epitopic fragment of said polypeptide, comprising the sequence SEQ ID No. 4, is provided along with its nucleic acid sequences. In addition, antibodies to the polypeptide and methods of diagnosing paraneoplastic neurological syndromes and/or for the early diagnosis of the formation of cancerous tumors are also provided.
    Type: Application
    Filed: September 12, 2018
    Publication date: April 25, 2019
    Inventors: Michele AGUERA, Jean-Christophe ANTOINE, Marie-Francoise BELIN, Jerome HONNORAT, Veronique ROGEMOND
  • Human ULIP/CRMP protein and use thereof in diagnosis and treatment of cancers and paraneoplastic neurological syndromes
    Patent number: 10087220
    Abstract: A purified polypeptide, designated ULIP6, comprising the amino acid sequence SEQ ID No. 2 or an epitopic fragment of said polypeptide, comprising the sequence SEQ ID No. 4, is provided along with its nucleic acid sequences. In addition, antibodies to the polypeptide and methods of diagnosing paraneoplastic neurological syndromes and/or for the early diagnosis of the formation of cancerous tumors are also provided.
    Type: Grant
    Filed: January 15, 2013
    Date of Patent: October 2, 2018
    Assignee: INSTITUT NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE (INSERM)
    Inventors: Michele Aguera, Jean-Christophe Antoine, Marie-Francoise Belin, Jerome Honnorat, Veronique Rogemond
  • Diagnosis of cancers and paraneoplastic neurological syndromes with novel human ULIP/CRMP protein
    Patent number: 8377645
    Abstract: A purified polypeptide, designated ULIP6, comprising the amino acid sequence SEQ ID No. 2 or an epitopic fragment of said polypeptide, comprising the sequence SEQ ID No. 4, is provided along with its nucleic acid sequences. In addition, antibodies to the polypeptide and methods of diagnosing paraneoplastic neurological syndromes and/or for the early diagnosis of the formation of cancerous tumors are also provided.
    Type: Grant
    Filed: February 11, 2008
    Date of Patent: February 19, 2013
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Michèle Aguera, Jean-Christophe Antoine, Marie-Françoise Belin, Jérôme Honnorat, Véronique Rogemond
  • Novel human ulip/CRMP protein and use thereof in diagnosis and treatment of cancers and paraneoplastic neurological syndromes
    Publication number: 20080226636
    Abstract: A purified polypeptide, designated ULIP6, comprising the amino acid sequence SEQ ID No. 2 or an epitopic fragment of said polypeptide, comprising the sequence SEQ ID No. 4, is provided along with its nucleic acid sequences. In addition, antibodies to the polypeptide and methods of diagnosing paraneoplastic neurological syndromes and/or for the early diagnosis of the formation of cancerous tumors are also provided.
    Type: Application
    Filed: February 11, 2008
    Publication date: September 18, 2008
    Inventors: Michele Aguera, Jean-Christophe Antoine, Marie-Francoise Belin, Jerome Honnorat, Veronique Rogemond
  • Use of a novel human ULIP6/CRMP protein in diagnosis of paraneoplastic neurological syndromes
    Patent number: 7329499
    Abstract: The invention concerns a purified polypeptide, called ULIP6, comprising an amino acid sequence SEQ ID NO 2, the nucleic acid coding for said polypeptide, a non-coding sequence in 3? of said encoding sequence and their use in diagnosis and treatment of cancers and paraneoplastic neurological syndromes.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: February 12, 2008
    Assignee: Institut National de la Sante et de la Recherche Medicale (Inserm)
    Inventors: Michèle Aguera, Jean-Christophe Antoine, Marie-Françoise Belin, Jérôme Honnorat, Véronique Rogemond
  • Use of ULIP proteins in the diagnosis and therapy of cancers and paraneoplastic neurological syndromes
    Publication number: 20070117166
    Abstract: The invention relates to the use of proteins designated ULIP/POP in the diagnosis and therapy of cancers and paraneoplastic neurological syndromes.
    Type: Application
    Filed: December 20, 2006
    Publication date: May 24, 2007
    Inventors: Michele Aguera, Marie-Francoise Belin, Jerome Honnorat, Pappachan Kolattukudy, ThanhTam Quach, Tamara Byk, Andre Sobel, Dominique Aunis, Jean-Christophe Antoine
  • Use of ULIP proteins in the diagnosis and therapy of cancers and paraneoplastic neurological syndromes
    Patent number: 7183400
    Abstract: The invention concerns a purified polypeptide, biologically active polypeptide derivative or fragment of said purified polypeptide, comprising an amino acid sequence selected among SEQ.ID. No. 2, No. 4, No. 6 and No. 8.
    Type: Grant
    Filed: February 19, 1998
    Date of Patent: February 27, 2007
    Assignee: Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Michèle Aguera, Marie-Françoise Belin, Jérôme Honnorat, Pappachan Kolattukudy, ThanhTam Quach, Tamara Byk, André Sobel, Dominique Aunis, Jean-Christophe Antoine
  • Novel human ulip/crmp protein and use thereof in diagnosis and treatment of cancers and paraneoplastic neurological syndromes
    Publication number: 20030176336
    Abstract: The invention concerns a purified polypeptide, called ULIP6, comprising an amino acid sequence SEQ ID NO 2, the nucleic acid coding for said polypeptide, a non-coding sequence in 3′ of said encoding sequence and their use in diagnosis and treatment of cancers and paraneoplastic neurological syndromes.
    Type: Application
    Filed: November 19, 2002
    Publication date: September 18, 2003
    Inventors: Michele Aguera, Jean-Christophe Antoine, Marie-Francoise Belin, Jerome Honnorat, Veronique Rogemond