Abstract: A package comprising an integrated device and a substrate coupled to the integrated device. The substrate comprises at least one dielectric layer and a plurality of interconnects. The plurality of interconnects include a plurality of post interconnects. The plurality of post interconnects include a post interconnect comprising a profile cross section that includes a trapezoid shape.

Abstract: Provided are methods for treatment and uses involving the administration of doses of engineered T cells for treating subjects with disease and conditions such as certain B cell malignancies, and related methods, compositions, uses and articles of manufacture. The engineered cells generally express recombinant receptors such as chimeric antigen receptors (CARs). In some embodiments, the disease or condition is acute lymphoblastic leukemia (ALL) or non-Hodgkin lymphoma (NHL). In some embodiments, the subject is within a particular range of age, such as subjects that are 25 years or less of age, such as pediatric subjects.