Abstract: The present invention relates to cell culture in bioreactors, such as flexible cellbag bioreactors. More closely the invention relates to a method and system for determining the cell density in a bioreactor culture and for controlling the perfusion rate of a suspension culture of cells in a bioreactor, comprising measuring the oxygen uptake of primary mononuclear cells in a non-static bioreactor.

Abstract: The invention relates to devices, methods and kits for separating biological materials, particularly populations of cells of different densities. The invention finds particular utility in the separation of blood into its different component parts or cellular populations. An insert for a centrifuge tube is disclosed that facilitates the effective separation of blood fractions by achieving a sharp and distinct interface between the density gradient medium and the blood sample. Methods and kits involving the use of the insert in separating cells are described.

Abstract: The invention relates to devices, methods and systems for collecting and solidifying waste material from bioreactor cell cultures in order to facilitate waste disposal. The invention finds particular utility in mammalian cell culture applications. A transverse wall divides the interior of a waste bag into two chambers, the first chamber containing an inlet receiving waste liquid from a bioreactor, the second chamber containing an absorbent material to solidify the liquid into a gel. The transverse wall acts to direct the flow of waste media into the second chamber where it is converted into a gel and further prevents the inlet from being blocked by any gel or particulate materials. Methods and uses regarding this invention are described.

Abstract: The present invention relates to systems and methods for optimising the usage of laboratory and cell culturing space for cell culture and biomanufacturing. The invention provides a system and method that can be used to provide a plurality of workstations and/or storage bays for bioreactors in cell culturing and/or biomanufacturing facilities.

Abstract: The invention relates to devices, methods and systems for collecting and solidifying waste material from bioreactor cell cultures in order to facilitate waste disposal. The invention finds particular utility in mammalian cell culture applications. A transverse wall divides the interior of a waste bag into two chambers, the first chamber containing an inlet receiving waste liquid from a bioreactor, the second chamber containing an absorbent material to solidify the liquid into a gel. The transverse wall acts to direct the flow of waste media into the second chamber where it is converted into a gel and further prevents the inlet from being blocked by any gel or particulate materials. Methods and uses regarding this invention are described.

Abstract: The invention relates to devices, methods and kits for separating biological materials, particularly populations of cells of different densities. The invention finds particular utility in the separation of blood into its different component parts or cellular populations. An insert for a centrifuge tube is disclosed that facilitates the effective separation of blood fractions by achieving a sharp and distinct interface between the density gradient medium and the blood sample. Methods and kits involving the use of the insert in separating cells are described.

Abstract: The present invention relates to cell culture in bioreactors, such as flexible cellbag bioreactors.

Abstract: The present invention relates to systems and methods for optimising the usage of laboratory and cell culturing space for cell culture and biomanufacturing. The invention provides a system and method that can be used to provide a plurality of workstations and/or storage bays for bioreactors in cell culturing and/or biomanufacturing facilities.