Patents by Inventor Micky Daniel Tortorella

Micky Daniel Tortorella has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBACTERIAL COMPOUNDS
    Publication number: 20220096437
    Abstract: Described are 1, 2, 4-substituted azetidine compounds of formula I, as well as pharmaceutical compositions and dosage forms comprising the compounds, and their use as a medicament. The compounds may find use as antibacterial agents, in particular against M. tuberculosis.
    Type: Application
    Filed: April 8, 2019
    Publication date: March 31, 2022
    Inventors: Cleopatra Daniela NEAGOIE, Xudan PENG, Micky Daniel TORTORELLA, John S. FOSSEY, Luke John ALDERWICK, Antonia FEULA, Akina YOSHIZAWA
  • Compositions and methods for inhibiting expression of ADAMTS-5 and ADAM17
    Patent number: 10709729
    Abstract: Provided are siRNAs or chemically-modified siRNAs targeted against ADAMTS-5 or ADAM17 for inhibiting the expression of ADAMTS-5 or ADAM17. Use of the siRNAs for treating an ADAMTS-5 or ADAM17 associated disease, such as arthritis and other inflammation-related diseases, by injecting the siRNAs or preparations comprising the siRNAs into an articular cavity of the patient, are also provided.
    Type: Grant
    Filed: December 23, 2015
    Date of Patent: July 14, 2020
    Assignees: GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES, GUANGZHOU RIBOBIO CO., LTD.
    Inventors: Bill Biliang Zhang, Micky Daniel Tortorella, Zhe Wang, Xiuqun Yang, Qiuyun Wang
  • COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF ADAMTS-5 AND ADAM17
    Publication number: 20180250323
    Abstract: Provided are siRNAs or chemically-modified siRNAs targeted against ADAMTS-5 or ADAM17 for inhibiting the expression of ADAMTS-5 or ADAM17. Use of the siRNAs for treating an ADAMTS-5 or ADAM17 associated disease, such as arthritis and other inflammation-related diseases, by injecting the siRNAs or preparations comprising the siRNAs into an articular cavity of the patient, are also provided.
    Type: Application
    Filed: December 23, 2015
    Publication date: September 6, 2018
    Inventors: Bill Biliang ZHANG, Micky Daniel TORTORELLA, Zhe WANG, Xiuqun YANG, Qiuyun WANG
  • Low binding liquid retaining and filtering device
    Patent number: 6544417
    Abstract: This invention is directed to filtrate-holder and reversible-well collection plates composed of polypropylene and Teflon® resin, and to their use, in connection with compatible filter units, in high-throughput screening assays for assessing the binding of small molecules to proteins.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: April 8, 2003
    Assignee: DuPont Pharmaceuticals, Inc.
    Inventor: Micky Daniel Tortorella