Patents by Inventor Mihaela Diana Danca

Mihaela Diana Danca has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteasome Inhibitors
    Publication number: 20240083922
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: November 17, 2023
    Publication date: March 14, 2024
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • Proteasome Inhibitors
    Publication number: 20230265110
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: May 2, 2023
    Publication date: August 24, 2023
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20220251117
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: April 14, 2022
    Publication date: August 11, 2022
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20220017542
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: September 29, 2021
    Publication date: January 20, 2022
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20210206784
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: March 19, 2021
    Publication date: July 8, 2021
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20200407376
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: September 9, 2020
    Publication date: December 31, 2020
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20200190118
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: February 20, 2020
    Publication date: June 18, 2020
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20190359636
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: August 7, 2019
    Publication date: November 28, 2019
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20190144470
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: January 17, 2019
    Publication date: May 16, 2019
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20180305380
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: June 29, 2018
    Publication date: October 25, 2018
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20180099984
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: December 7, 2017
    Publication date: April 12, 2018
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • PROTEASOME INHIBITORS
    Publication number: 20150361105
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: August 24, 2015
    Publication date: December 17, 2015
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • Proteasome Inhibitors
    Publication number: 20150011506
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: September 22, 2014
    Publication date: January 8, 2015
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • Proteasome inhibitors
    Patent number: 8871745
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Grant
    Filed: August 12, 2013
    Date of Patent: October 28, 2014
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • Proteasome inhibitors
    Patent number: 8772536
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Grant
    Filed: August 12, 2013
    Date of Patent: July 8, 2014
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • Proteasome Inhibitors
    Publication number: 20130331595
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: August 12, 2013
    Publication date: December 12, 2013
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • Proteasome Inhibitors
    Publication number: 20130331356
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Application
    Filed: August 12, 2013
    Publication date: December 12, 2013
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • Proteasome inhibitors
    Patent number: 8530694
    Abstract: The present invention provides novel compounds useful as proteasome inhibitors. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various diseases.
    Type: Grant
    Filed: August 15, 2011
    Date of Patent: September 10, 2013
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Edward J. Olhava, Mihaela Diana Danca
  • Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
    Patent number: 8273891
    Abstract: The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nACh receptors), activation of nACh receptors, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (e.g., indazoles and benzothiazoles), which act as ligands for the ?7 nACh receptor subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
    Type: Grant
    Filed: February 5, 2010
    Date of Patent: September 25, 2012
    Assignee: Memory Pharmaceuticals Corporation
    Inventors: Richard Schumacher, Mihaela Diana Danca, Jianguo Ma, Brian Herbert, True Minh Nguyen, Wenge Xie, Ashok Tehim
  • Certain substituted ureas, as modulators of kinase activity
    Patent number: 8222421
    Abstract: Certain chemical entities chosen from compounds of Formula 1 and pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, and prodrugs thereof, are provided herein. Pharmaceutical compositions comprising at least one chemical entity and one or more pharmaceutically acceptable vehicles chosen from carriers, adjuvants, and excipients, are also provided herein. Methods of treating patients suffering from certain diseases and disorders responsive to angiogenic kinase modulation, which comprise administering to such patients an amount of at least one chemical entity effective to reduce signs or symptoms of the disease or disorder are disclosed. These diseases include cancer, including breast neoplasia, endometrial cancer, colon cancer, and neck squamous cell carcinoma. Methods of treatment include administering at least one chemical entity as a single active agent or administering such at least one chemical entity in combination with one or more other therapeutic agents.
    Type: Grant
    Filed: July 20, 2010
    Date of Patent: July 17, 2012
    Assignee: Gilead Connecticut, Inc.
    Inventors: Scott A. Mitchell, Mihaela Diana Danca, Peter A. Blomgren, David R. Brittelli, Pavel Zhichkin, Matthew E. Voss