Patents by Inventor Mikio Kabaki

Mikio Kabaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8017793
    Abstract: Disclosed is a method for oxidizing an alcohol in an amide solvent using a mixed reagent containing hydrogen peroxide and a tungsten catalyst.
    Type: Grant
    Filed: May 12, 2005
    Date of Patent: September 13, 2011
    Assignee: Shionogi & Co., Ltd.
    Inventors: Takemasa Hida, Kyozo Kawata, Mikio Kabaki
  • Publication number: 20080269509
    Abstract: Disclosed is a method for oxidizing an alcohol in an amide solvent using a mixed reagent containing hydrogen peroxide and a tungsten catalyst.
    Type: Application
    Filed: May 12, 2005
    Publication date: October 30, 2008
    Inventors: Takemasa Hida, Kyozo Kawata, Mikio Kabaki
  • Patent number: 6844437
    Abstract: The invention concerns a process for the manufacture of tert-butyl (E)-(6-[2-4-(4-flourophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl)-(4R,6S)-2,2-dimethyl[1,3]-dioxan-4-yl)acetate, the novel starting material used in said process and the use of the process in the manufacture of a pharmaceutical.
    Type: Grant
    Filed: February 15, 2000
    Date of Patent: January 18, 2005
    Assignees: Astrazeneca AB, Shionogi & Co. Ltd.
    Inventors: Nigel P Taylor, Loius J Diorazio, Haruo Koike, Mikio Kabaki
  • Patent number: 6784171
    Abstract: The invention concerns a process for the manufacture of tert-butyl (E)-(6-[2-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl)-(4R, 6S)-2,2-dimethyl(1,3-dioxan-4-yl) acetate, the novel starting material used in said process and the use of the process in the manufacture of a pharmaceutical.
    Type: Grant
    Filed: July 2, 2003
    Date of Patent: August 31, 2004
    Assignee: AstraZeneca
    Inventors: Nigel P Taylor, Loius J Diorazio, Haruo Koike, Mikio Kabaki
  • Publication number: 20040049036
    Abstract: The invention concerns a process for the manufacture of tert-butyl (E)-(6-[2-4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]vinyl}-(4R, 6S)-2,2-dimethyl[1,3-dioxan-4-yl) acetate, the novel starting material used in said process and the use of the process in the manufacture of a pharmaceutical.
    Type: Application
    Filed: July 2, 2003
    Publication date: March 11, 2004
    Applicants: ASTRAZENECA AB, SHIONOGI & CO., LTD.
    Inventors: Nigel P. Taylor, Louis Diorazio, Haruo Koike, Mikio Kabaki
  • Patent number: 6057448
    Abstract: The present invention provides a process for producing a compound of the formula (III): ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen or an organic group; R.sup.2 is an organic group; and R.sup.4 is an optionally substituted aryl. by reacting the compound of formula (I): ##STR2## wherein R.sup.1, R.sup.2, and R.sup.3 are as defined above, with the compound of formula (II):R.sup.4 --S--Hal (II)wherein R.sup.4 is as defined above and Hal is halogen, in the presence of base.
    Type: Grant
    Filed: June 10, 1999
    Date of Patent: May 2, 2000
    Assignee: Shionogi & Co., Ltd.
    Inventors: Makoto Hajima, Yasuyuki Hozumi, Mikio Kabaki
  • Patent number: 6015921
    Abstract: A method for preparing carbamoylmethylurea derivatives of the formula (I): ##STR1## characterized by reacting a compound of the formula (II): ##STR2## with a compound of the formula (III): ##STR3##
    Type: Grant
    Filed: February 3, 1998
    Date of Patent: January 18, 2000
    Assignee: Shionogi & Co., Ltd.
    Inventors: Haruo Koike, Yasufumi Ueda, Koji Matsuda, Mikio Kabaki