Patents by Inventor Mikio Kinoshita
Mikio Kinoshita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240124571Abstract: Provided is a substance capable of effectively suppressing cancer metastasis or a pharmaceutical composition that effectively acts on an inflammatory disease. The pharmaceutical composition is a pharmaceutical composition containing, as an active ingredient, an antibody or an antibody fragment thereof having antigen-binding activity for an S100A8/A9 heterodimer, and blocks interaction between S100A8/A9 and a group of receptors therefor, to thereby strongly suppress cancer metastasis both in vitro and in vivo, or alleviate inflammation. That is, the anti-S100A8/A9 antibody or the antibody fragment thereof can strongly suppress cancer metastasis or alleviate inflammation, by virtue of its blocking action on the interaction between S100A8/A9 and the group of receptors therefor.Type: ApplicationFiled: November 17, 2023Publication date: April 18, 2024Applicant: National University Corporation Okayama UniversityInventors: Masakiyo SAKAGUCHI, Shinichi TOYOOKA, Shuta TOMIDA, Kazuhiko SHIEN, Hiroki SATO, Rie KINOSHITA, Junichiro FUTAMI, Kota ARAKI, Mikio OKAZAKI, Eisaku KONDO, Yusuke INOUE, Akira YAMAUCHI
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Publication number: 20090123445Abstract: The present invention relates to a composition for controlling scab disease in agricultural products, which comprises a compound of Formula I or a salt thereof. The present invention further relates to a method for controlling scab disease in agricultural products by using a composition for controlling scab disease, which comprises a compound of Formula I or a salt thereof.Type: ApplicationFiled: September 28, 2006Publication date: May 14, 2009Inventors: Takeshi Saeki, Hajime Komura, Takuji Ohwada, Mikio Kinoshita
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Publication number: 20060282907Abstract: To provide meat that is beneficial to human health, for the purpose to produce transgenic animals in which the content of unsaturated fatty acids increase is increased, transgenic animals characterized by increased content of unsaturated fatty acids that are beneficial to human health is provided by the present invention. Furthermore, the present invention also provides a method to enhance levels of unsaturated fatty acid in animals.Type: ApplicationFiled: January 30, 2003Publication date: December 14, 2006Applicants: KINKI UNIVERSITY, JAPAN SOCIETY FOR THE PROMOTION OF SCIENCEInventors: Kazuhiro Saeki, Kazuya Matsumoto, Mikio Kinoshita, Iwane Suzuki, Yoshitomo Taguchi, Koji Mikami, Masatsugu Ueda, Yoshihiro Hosoi, Norio Murata, Akira Iritani, Kouichiro Kano
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Patent number: 7036327Abstract: A cooling system comprising an evaporation cooling device for evaporating an aqueous solution, a water content providing device for allowing vapor evaporated from impurities-containing water to be absorbed into the aqueous solution, and a circulating device for circulating the aqueous solution between the water content providing device and the evaporation cooling device; and a cooling method characterized by comprising the steps of taking in impurities-containing water, cooling a high-temperature body by evaporating water content in an aqueous solution having a boiling point higher than that of the impurities-containing water, allowing vapor evaporated from the impurities containing water to be absorbed into the aqueous solution concentrated by the cooling step, feeding the aqueous solution diluted in the absorbing step to the cooling step, and discharging the impurities-containing water concentrated in the absorbing step.Type: GrantFiled: February 1, 2000Date of Patent: May 2, 2006Inventor: Mikio Kinoshita
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Patent number: 6945246Abstract: A solar radiation reflector comprising a plurality of arms arranged in parallel, a plurality of driver mechanisms driven, respectively, by the arms, a plurality of reflectors turned, respectively, by the driven mechanisms, a plurality of reflection direction designating members connected, respectively, with the driven mechanisms to designate a predetermined direction of reflection of reflectors, respectively, a common link for turning the arms simultaneously, and a drive mechanism for driving the common link to direct the arms in parallel with the incident direction of solar radiation, and a solar energy system comprising the solar radiation reflector and a solar energy converter. The driven mechanisms driven simultaneously by the driving mechanism through the common link and the arms so that the reflectors may reflect solar radiation, respectively, toward specified directions turn the reflectors, respectively.Type: GrantFiled: February 9, 2001Date of Patent: September 20, 2005Inventor: Mikio Kinoshita
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Publication number: 20040233554Abstract: A solar radiation condensing device (1), characterized by comprising a plurality of reflectors (10) disposed on a reflector arrangement surface, reference point providing members (20) for determining the reference points for the rotating motions of the plurality of reflectors, and a cam mechanism (30) for simultaneously rotating the plurality of reflectors around the reference points, the cam mechanism further comprising a cam (40) of such a specified shape that the plurality of reflectors can condense an incident solar radiation, a plurality of probes (60, 70) coming into contact with the plurality of reflectors, and unshown guide members for storing the plurality of probes, wherein a rotating mechanism (90) for rotating the plurality of reflectors around a straight line perpendicular to the reflector arrangement surface so that the incident solar radiation (S) is positioned along a specified incident direction area is disposed in an XYZ moving coordinate system moving along with the reflector arrangement suType: ApplicationFiled: June 23, 2003Publication date: November 25, 2004Inventor: Mikio Kinoshita
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Patent number: 6820611Abstract: A solar radiation concentrator rotated about a straight line vertical to the reflector arrangement surfaces so that the incident solar radiation can be led onto the reflector arrangement surface along the specified direction and a method of concentrating solar radiation; the concentrator, comprising a plurality of reflectors (10) disposed on reflector arrangement surfaces, a plurality of reflector vertical bars (20) connected to the plurality of reflectors, rotating center holding members (30) for holding the center points of the rotating motions of the plurality of reflector vertical bars, motion members (40) for collectively rotating the plurality of reflector vertical bars, and guide members (50) for guiding the motions of the plurality of reflector vertical bars so that the plurality of reflector vertical bars can be rotated along specified reflector vertical bar routes, wherein the motion members perform motions along the specified motion member routes according to a variation in the incident angle of thType: GrantFiled: April 28, 2003Date of Patent: November 23, 2004Inventor: Mikio Kinoshita
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Publication number: 20040159318Abstract: A solar radiation concentrator rotated about a straight line vertical to the reflector arrangement surfaces so that the incident solar radiation can be led onto the reflector arrangement surface along the specified direction and a method of concentrating solar radiation; the concentrator, comprising a plurality of reflectors (10) disposed on reflector arrangement surfaces, a plurality of reflector vertical bars (20) connected to the plurality of reflectors, rotating center holding members (30) for holding the center points of the rotating motions of the plurality of reflector vertical bars, motion members (40) for collectively rotating the plurality of reflector vertical bars, and guide members (50) for guiding the motions of the plurality of reflector vertical bars so that the plurality of reflector vertical bars can be rotated along specified reflector vertical bar routes, wherein the motion members perform motions along the specified motion member routes according to a variation in the incident angle of thType: ApplicationFiled: February 20, 2004Publication date: August 19, 2004Inventor: Mikio Kinoshita
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Publication number: 20040098998Abstract: A solar thermal system, comprising a solar pond (10) for accumulating salt water heated by solar radiation and a moisture supply device (20) allowing the vapor evaporated from the water having impurities such as sea water to be absorbed by the salt water; a method of maintaining the solar pond; and a method of forming the solar pond; the system, wherein the moisture supply device may have an absorbing heat pump for receiving the supply of the salt water and the water having the impurities, and the salt water with excellent cleanliness is circulated to the solar pond by the operation of the moisture supply device, whereby scale deposit and propagation of algae in the solar pond can be prevented.Type: ApplicationFiled: September 7, 2003Publication date: May 27, 2004Inventor: Mikio Kinoshita
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Publication number: 20040031483Abstract: A solar radiation concentrator rotated about a straight line vertical to the reflector arrangement surfaces so that the incident solar radiation can be led onto the reflector arrangement surface along the specified direction and a method of concentrating solar radiation; the concentrator, comprising a plurality of reflectors (10) disposed on reflector arrangement surfaces, a plurality of reflector vertical bars (20) connected to the plurality of reflectors, rotating center holding members (30) for holding the center points of the rotating motions of the plurality of reflector vertical bars, motion members (40) for collectively rotating the plurality of reflector vertical bars, and guide members (50) for guiding the motions of the plurality of reflector vertical bars so that the plurality of reflector vertical bars can be rotated along specified reflector vertical bar routes, wherein the motion members perform motions along the specified motion member routes according to a variation in the incident angle of thType: ApplicationFiled: April 28, 2003Publication date: February 19, 2004Inventor: Mikio Kinoshita
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Publication number: 20030136397Abstract: A solar radiation reflector comprising a plurality of arms arranged in parallel, a plurality of driver mechanisms driven, respectively, by the arms, a plurality of reflectors turned, respectively, by the driven mechanisms, a plurality of reflection direction designating members connected, respectively, with the driven mechanisms to designate a predetermined direction of reflection of reflectors, respectively, a common link for turning the arms simultaneously, and a drive mechanism for driving the common link to direct the arms in parallel with the incident direction of solar radiation, and a solar energy system comprising the solar radiation reflector and a solar energy converter. The driven mechanisms driven simultaneously by the driving mechanism through the common link and the arms so that the reflectors may reflect solar radiation, respectively, toward specified directions turn the reflectors, respectively.Type: ApplicationFiled: December 22, 2002Publication date: July 24, 2003Inventor: Mikio Kinoshita
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Patent number: 6349563Abstract: A salt water desalinating device, characterized by having an absorption refrigerating machine using a first dilute salt water and concentrated salt water and characterized in that a second dilute salt water to be desalinated is evaporated by heat flowing out from the high-temperature heat source of the absorption refrigerating machine and vapor evaporated from the second dilute salt water is condensed by heat to be absorbed to a refrigeration source. A plurality of the absorption refrigerating machines may be series-connected in a series arrangement.Type: GrantFiled: September 26, 2000Date of Patent: February 26, 2002Inventor: Mikio Kinoshita
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Patent number: 6096398Abstract: A phase-change optical recording medium has a substrate, and a lower heat-resistant protective layer, a recording layer capable of recording and erasing information by utilizing changes in the phase of a phase-change recording material in the recording layer, an upper heat-resistant protective layer and a light reflecting and heat dissipating layer, which are successively overlaid on the substrate in this order, the recording material including Ag, In, Sb and Te as the main elements, at least one additional element selected from the group (1) consisting of B, C, N, Al, Si and P, and at least one additional element selected from the group (2) consisting of halogen atoms and alkali metal elements.Type: GrantFiled: November 25, 1998Date of Patent: August 1, 2000Assignee: Ricoh Company, Ltd.Inventors: Hajime Yuzurihara, Hiroshi Deguchi, Michiaki Shinotsuka, Takashi Shibaguchi, Makoto Harigaya, Mikio Kinoshita, Yoshiyuki Kageyama, Michiharu Abe
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Patent number: 5948496Abstract: An optical recording medium includes a substrate, a first protection layer formed on the substrate, a recording layer formed on the first protection layer, a second protection layer formed on the recording layer, and a reflection heat radiating layer formed on the second protection layer. The recording layer is of a phase-change type in which the recording layer is changed from an amorphous state to a crystal state by a temperature raising and cooling process by projecting a laser beam onto the recording layer. The recording layer has an interface portion interfaced with one of the first and second protection layers. The interface portion has a thermal conductivity lower than that of a remaining portion of the recording layer.Type: GrantFiled: March 26, 1997Date of Patent: September 7, 1999Assignee: Ricoh Company, Ltd.Inventors: Mikio Kinoshita, Makoto Harigaya
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Patent number: 5875160Abstract: A device for initializing an optical recording medium includes a semiconductor laser diode, and an optical system which projects a laser beam emitted from the semiconductor laser diode onto the optical recording medium. A half-value width of a spot of the laser beam focused on the optical recording medium is equal to 1/2 to 1/6 times a half-value width of a near-field pattern of the semiconductor laser diode in a direction parallel to a junction interface of the semiconductor laser diode, so that the optical recording medium can be evenly initialized by the laser beam.Type: GrantFiled: March 25, 1997Date of Patent: February 23, 1999Assignee: Ricoh Company, Ltd.Inventors: Makoto Harigaya, Mikio Kinoshita, Yoshiyuki Kageyama
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Patent number: 5465475Abstract: A thin film magnetic head has a lower magnetic pole formed on a substrate; a coil arranged on the lower magnetic pole through an adhesive layer; an upper magnetic pole arranged on the coil; and a gap layer formed between the upper and lower magnetic poles. A method for forming the thin film magnetic head has a process for forming a lower magnetic pole on a first substrate; a process for forming a coil on a second substrate having a recessed portion; a process for polishing the first and/or second substrate such that a face of the lower magnetic pole on the first substrate and a face of the coil on the second substrate come in close contact with each other; a process for adhering the first and second substrates to each other such that the lower magnetic pole and the coil are adjacent to each other; a process for forming a gap layer on the lower magnetic pole; a process for polishing or etching a portion or all of the second substrate; and a process for forming an upper magnetic pole.Type: GrantFiled: July 29, 1993Date of Patent: November 14, 1995Assignee: Ricoh Co., Ltd.Inventors: Mikio Kinoshita, Wasaburo Ohta
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Patent number: 5427668Abstract: A thin film deposition system includes a vacuum or evacuated casing in which there is introduced an active gas or an inert gas or a mixture thereof. A filament emits thermions which impinge upon gas molecules to ionize them into positive ions. The ions bombard a target, from which particles are emitted toward a substrate. The particles emitted from the target are also ionized by the thermions. In the vicinity of a grid, more particles from the target are ionized by thermions which are vertically oscillated and ionized molecules of the gas. The ions are accelerated toward the substrate and bombard the substrate, thereby depositing a thin film thereon. The thin film deposition system may additionally have an evaporation source for supporting an evaporant which emit particles to be deposited on the substrate.Type: GrantFiled: October 22, 1990Date of Patent: June 27, 1995Assignee: Ricoh Company, Ltd.Inventors: Tatsuya Sato, Wasaburo Ohta, Mikio Kinoshita
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Patent number: 5266837Abstract: An apparatus for artificial wind power generation comprises a container which is constructed of, or supported by, a membrane structure formed of a plurality of gastight cells. The container is provided with an air inlet disposed at a lower part of the container for allowing heated and/or humidified air to be introduced, and an air outlet disposed at an upper part of the container. The apparatus is also provided with a wind power conversion mechanism, and an electric power generator.Type: GrantFiled: March 25, 1992Date of Patent: November 30, 1993Inventor: Mikio Kinoshita
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Patent number: 5133849Abstract: An apparatus for forming a thin film has a vacuum container to which an active gas, an inert gas or a mixture thereof is introduced, and a source of evaporation from which a substance is evaporated. A counter electrode is disposed in the vacuum container for holding a substrate for forming a thin film thereon in such a manner as to be opposed to the source of evaporation. A grid is disposed between the source of evaporation and the counter electrode and having openings which allow the evaporated substance to pass therethrough. A filament for thermionic emission is disposed between the grid and the source of evaporation. A target is also disposed between the filament and the source of evaporation for emitting sputtered particles. A power source device establishes predetermined electric potential relationships between the grid, the filament, and the target.Type: GrantFiled: December 11, 1989Date of Patent: July 28, 1992Assignee: Ricoh Company, Ltd.Inventors: Mikio Kinoshita, Wasaburo Ohta, Tatsuya Sato, Masashi Nakazawa
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Patent number: 5114559Abstract: A thin film deposition system includes an evacuated casing in which there is introduced an active gas or an inert gas or a mixture thereof. An evaporant carried by an evaporation source in the evacuated casing is evaporated and travels toward a substrate supported on the electrode. A filament for emitting thermions is disposed between the evaporation source and the electrode, and a grid for passing the evaporated material therethrough is disposed between the filament and the electrode. Power supplies are electrically connected to the evacuated casing, the evaporation source, the electrode, the filament, and the grid, for keeping the filament negative in potential with respect to the evacuated casing and the grid. Alternatively, the evacuated casing may not be connected to the power supplies so that the grid is kept positive with respect to the filament. The grid may be of a double-layer structure, with the gas inlet means connected to the grid.Type: GrantFiled: September 25, 1990Date of Patent: May 19, 1992Assignee: Ricoh Company, Ltd.Inventors: Wasaburo Ohta, Masashi Nakazawa, Mikio Kinoshita