Patents by Inventor Min-Hyo Seo

Min-Hyo Seo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11980610
    Abstract: Disclosed are an oral solid dosage form composition comprising an active ingredient and a solubilizing carrier wherein a foaming ingredient is used to improve disintegration, dispersion or dissolution, and a preparation method therefor.
    Type: Grant
    Filed: October 30, 2018
    Date of Patent: May 14, 2024
    Assignee: SAMYANG HOLDINGS CORPORATION
    Inventors: Sang Yeob Park, Hye Jung Lim, Jae Young Lee, Min Hyo Seo, Sa Won Lee
  • Publication number: 20240024532
    Abstract: The present invention relates to novel microspheres using an anionic polymer, a preparation method thereof, a composition, and the like, and the present invention is used for a method for performing a vascular embolization and/or necrosing cancer cells by blocking major blood vessels that supply nutrients to cancer cells to induce an embolic effect, and thus may be used for the treatment of patients with cancer.
    Type: Application
    Filed: July 31, 2023
    Publication date: January 25, 2024
    Inventors: Dongyeon KIM, Ha Hee SHIN, Eun Ah JUNG, Hyungwon MOON, Min Hyo SEO
  • Patent number: 11793762
    Abstract: The invention disclosed herein relates to a composition and method of reducing the joint pain associated with hemarthrosis or hemophilic arthropathy. The method includes administering a COX-2 inhibitor, such as rofecoxib, celecoxib, valdecoxib, etoricoxib or other “coxib” drug which is encapsulated in PLGA micro-particles. The COX-2 inhibitor can be administered directly to an area where pain exists by an injection device. In a preferred embodiment, rofecoxib or celecoxib can be encapsulated in PLGA micro-particles for controlled, sustained release over a 2-8-week period. The non-systemic delivery and the controlled, sustained release of rofecoxib alleviate the cardiovascular side effects associated with systemic rofecoxib treatments.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: October 24, 2023
    Inventors: Soonkap Hahn, Gantumur Battogtokh, Oyuntuya Gotov, Gil Man Kim, Min Hyo Seo
  • Patent number: 11571429
    Abstract: A medicament set adapted to regulate multiple receptors simultaneously in patients experiencing diabetic peripheral neuropathy pain, the medicament set comprising: at least three distinct and separate medicaments for treating diabetic peripheral neuropathy pain, the at least three medicaments being a first medicament for treating peripheral neuropathy pain, being formulated for clinical administration as a locally injectable medicament using an injection device, and comprising polylactic glycolic acid (PLGA) micro-particles being loaded with a sodium channel blocker and local anesthetic drug, a second medicament for treating peripheral neuropathy pain, being formulated for clinical administration as a locally injectable medicament using an injection device, and comprising PLGA micro-particles being loaded with a sodium channel blocker and anti-convulsant drug, and a third medicament for treating peripheral neuropathy pain, being formulated for clinical administration as a locally injectable medicament using a
    Type: Grant
    Filed: December 28, 2020
    Date of Patent: February 7, 2023
    Inventors: Soon Kap Hahn, Gantumur Battogtokh, Oyuntuya Gotov, Gil Man Kim, Min Hyo Seo
  • Patent number: 11464861
    Abstract: A pharmaceutical composition containing a specific related compound within a specified limit and a method for preparing the same are provided.
    Type: Grant
    Filed: April 24, 2020
    Date of Patent: October 11, 2022
    Assignee: SAMYANG HOLDINGS CORPORATION
    Inventors: Bong Oh Kim, Bum Chan Min, Ji Yeong Kim, Hye Rim Kim, Min Hyo Seo, Sa Won Lee, Yil Woong Yi, Joong Woong Cho, In Ja Choi
  • Publication number: 20220125929
    Abstract: Disclosed are a pharmaceutical composition for anionic drug delivery, and a preparation method therefor, the pharmaceutical composition for anionic drug delivery containing: an anionic drug as an active ingredient; a cationic compound; an amphiphilic block copolymer; and a polylactate, wherein the anionic drug formed a complex with the cationic lipid, and the complex is encapsulated within a micelle structure formed by the amphiphilic block copolymer and the polylactate.
    Type: Application
    Filed: January 10, 2022
    Publication date: April 28, 2022
    Applicant: SAMYANG HOLDINGS CORPORATION
    Inventors: Hye Yeong NAM, Bong-Oh KIM, Min-Hyo SEO, Ji-Yeon SON, Ji-Hye CHOI, Sang Hoon KIM
  • Patent number: 11253598
    Abstract: Disclosed are a pharmaceutical composition for anionic drug delivery, and a preparation method therefor, the pharmaceutical composition for anionic drug delivery containing: an anionic drug as an active ingredient; a cationic compound; an amphiphilic block copolymer; and a polylactate, wherein the anionic drug formed a complex with the cationic lipid, and the complex is encapsulated within a micelle structure formed by the amphiphilic block copolymer and the polylactate.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: February 22, 2022
    Inventors: Hye Yeong Nam, Bong-Oh Kim, Min-Hyo Seo, Ji-Yeon Son, Ji-Hye Choi, Sang Hoon Kim
  • Publication number: 20220000782
    Abstract: Provided herein are methods and compositions for treatment of a patient having a wound resulting from surgical resection of a tumor mass. In some embodiments, the methods provided herein include administering to the entirety of the wound area a composition before the wound area is closed, the composition having a first plurality of micro-particles comprising PLGA and one or more cancer treatment drugs, and a second plurality of micro-particles comprising PLGA and one or more wound healing drugs; wherein the wound healing drugs are released for a first period of time and the cancer treatment drugs are released for a second period of time without an initial burst release.
    Type: Application
    Filed: September 16, 2021
    Publication date: January 6, 2022
    Inventors: Soon Kap Hahn, Gantumur Battogtokh, Oyuntuya Gotov, Gil Man Kim, Min Hyo Seo
  • Patent number: 11077099
    Abstract: The present disclosure relates to an oral tablet composition comprising lenalidomide and a method for preparing the same. More particularly, the present disclosure relates to a tablet-type composition and a method for preparing the same wherein the composition exhibits physicochemical equivalence with lenalidomide preparations of hard capsules, has the same pharmacological, therapeutic effect in non-clinical studies and bioequivalence studies, and also has improved ease of taking, handling, safety and the like.
    Type: Grant
    Filed: September 11, 2017
    Date of Patent: August 3, 2021
    Assignee: SAMYANG HOLDINGS CORPORATION
    Inventors: Sang Yeob Park, Hye Jung Lim, Sa Won Lee, Min Hyo Seo
  • Publication number: 20210113583
    Abstract: A medicament set adapted to regulate multiple receptors simultaneously in patients experiencing diabetic peripheral neuropathy pain, the medicament set comprising: at least three distinct and separate medicaments for treating diabetic peripheral neuropathy pain, the at least three medicaments being a first medicament for treating peripheral neuropathy pain, being formulated for clinical administration as a locally injectable medicament using an injection device, and comprising polylactic glycolic acid (PLGA) micro-particles being loaded with a sodium channel blocker and local anesthetic drug, a second medicament for treating peripheral neuropathy pain, being formulated for clinical administration as a locally injectable medicament using an injection device, and comprising PLGA micro-particles being loaded with a sodium channel blocker and anti-convulsant drug, and a third medicament for treating peripheral neuropathy pain, being formulated for clinical administration as a locally injectable medicament using a
    Type: Application
    Filed: December 28, 2020
    Publication date: April 22, 2021
    Inventors: Soon Kap Hahn, Gantumur Battogtokh, Oyuntuya Gotov, Gil Man Kim, Min Hyo Seo
  • Publication number: 20200352869
    Abstract: The invention disclosed herein relates to a composition and method of reducing the joint pain associated with hemarthrosis or hemophilic arthropathy. The method includes administering a COX-2 inhibitor, such as rofecoxib, celecoxib, valdecoxib, etoricoxib or other “coxib” drug which is encapsulated in PLGA micro-particles. The COX-2 inhibitor can be administered directly to an area where pain exists by an injection device. In a preferred embodiment, rofecoxib or celecoxib can be encapsulated in PLGA micro-particles for controlled, sustained release over a 2-8-week period. The non-systemic delivery and the controlled, sustained release of rofecoxib alleviate the cardiovascular side effects associated with systemic rofecoxib treatments.
    Type: Application
    Filed: July 28, 2020
    Publication date: November 12, 2020
    Inventors: Soonkap Hahn, Gantumur Battogtokh, Oyuntuya Gotov, Gil Man Kim, Min Hyo Seo
  • Patent number: 10793516
    Abstract: Disclosed is a method capable of selectively synthesizing cationic lipids by controlling the introduction rate of a fatty acid group with respect to an oligoalkyleneamine by the change of reaction conditions.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: October 6, 2020
    Assignee: SAMYANG BIOPHARMACEUTICALS CORPORATION
    Inventors: Sungwon Choi, Hye Yeong Nam, Min-Hyo Seo
  • Patent number: 10765753
    Abstract: The present invention relates to a polymer nanoparticle freeze-dried product, and a preparation method therefor, the polymer nanoparticle freeze-dried product being obtainable by treating, through a freeze-drying process comprising an annealing step, a polymer nanoparticle aqueous solution comprising an amphiphilic block copolymer, a polylactic acid derivative having a carboxyl terminal group, and a freeze-drying adjuvant, wherein the polymer nanoparticle freeze-dried product is reconstituted within five minutes upon reconstitution by means of an aqueous solvent under atmospheric pressure.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: September 8, 2020
    Assignee: SAMYANG BIOPHARMACEUTICALS CORPORATION
    Inventors: Sa Won Lee, Gyeong Hae Kim, Min Hyo Seo
  • Publication number: 20200261426
    Abstract: Disclosed are an oral solid dosage form composition comprising an active ingredient and a solubilizing carrier wherein a foaming ingredient is used to improve disintegration, dispersion or dissolution, and a preparation method therefor.
    Type: Application
    Filed: October 30, 2018
    Publication date: August 20, 2020
    Applicant: SAMYANG BIOPHARMACEUTICALS CORPORATION
    Inventors: Sang Yeob PARK, Hye Jung LIM, Jae Young LEE, Min Hyo SEO, Sa Won LEE
  • Patent number: 10739319
    Abstract: A method for analyzing related substances in a pharmaceutical composition containing an amphiphilic block copolymer comprising a hydrophilic block and a hydrophobic block as a polymeric drug carrier, related substances identified thereby, and a method for evaluating a pharmaceutical composition by using the same are provided. Preferably, the method comprises evaluating a polymeric micelle pharmaceutical composition, which comprises an amphiphilic block copolymer comprising a hydrophilic block (A) and a hydrophobic block (B), and paclitaxel or docetaxel as a poorly water-soluble drug, by using a compound represented by Chemical Formula 1, wherein the hydrophilic block (A) comprises one or more selected from the group consisting of polyethylene glycol or derivatives thereof, polyvinylpyrrolidone, polyvinyl alcohol, polyacrylamide and combinations thereof; and the hydrophobic block (B) is polylactide.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: August 11, 2020
    Assignee: SAMYANG BIOPHARMACEUTICALS CORPORATION
    Inventors: Hye Rim Kim, Ji Yeong Kim, Bum Chan Min, Min Hyo Seo, Ho Joon Choi
  • Publication number: 20200246468
    Abstract: A pharmaceutical composition containing a specific related compound within a specified limit and a method for preparing the same are provided.
    Type: Application
    Filed: April 24, 2020
    Publication date: August 6, 2020
    Applicant: SAMYANG BIOPHARMACEUTICALS CORPORATION
    Inventors: Bong Oh KIM, Bum Chan MIN, Ji Yeong KIM, Hye Rim KIM, Min Hyo SEO, Sa Won LEE, Yil Woong YI, Joong Woong CHO, In Ja CHOI
  • Publication number: 20200078463
    Abstract: Disclosed are: a composition having improved water solubility and bioavailability, containing sorafenib and a polymethacrylate copolymer; and a preparation method therefor.
    Type: Application
    Filed: April 30, 2018
    Publication date: March 12, 2020
    Applicant: SAMYANG BIOPHARMACEUTICALS CORPORATION
    Inventors: Sang Yeob PARK, Hye Jung LIM, Sa Won LEE, Min Hyo SEO
  • Publication number: 20200038390
    Abstract: The present disclosure relates to an oral tablet composition comprising lenalidomide and a method for preparing the same. More particularly, the present disclosure relates to a tablet-type composition and a method for preparing the same wherein the composition exhibits physicochemical equivalence with lenalidomide preparations of hard capsules, has the same pharmacological, therapeutic effect in non-clinical studies and bioequivalence studies, and also has improved ease of taking, handling, safety and the like.
    Type: Application
    Filed: September 11, 2017
    Publication date: February 6, 2020
    Applicant: SAMYANG BIOPHARMACEUTICALS CORPORATION
    Inventors: Sang Yeob PARK, Hye Jung LIM, Sa Won LEE, Min Hyo SEO
  • Patent number: 10456362
    Abstract: Provided are a composition containing an unstable drug against oxidation like pemetrexed with improved stability and a preparation method thereof, by removing oxygen during the preparation. The method is readily applicable for manufacturing by freezing and degassing in a sealed chamber, and can provide formulations with significantly increased stability for the unstable drug against oxidation.
    Type: Grant
    Filed: May 27, 2016
    Date of Patent: October 29, 2019
    Assignee: SAMYANG BIOPHARMACEUTICALS CORPORATION
    Inventors: Joong-Woong Cho, Gyeong-Hae Kim, Min-Hyo Seo, Sa-Won Lee
  • Patent number: 10358411
    Abstract: Disclosed is a method capable of selectively synthesizing cationic lipids by controlling the introduction rate of a fatty acid group with respect to an oligoalkyleneamine by the change of reaction conditions.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: July 23, 2019
    Assignee: SAMYANG BIOPHARMACEUTICALS CORPORATION
    Inventors: Sungwon Choi, Hye Yeong Nam, Min-Hyo Seo