Patents by Inventor Ming Ding

Ming Ding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11549112
    Abstract: The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents, able to inhibit xanthine dehydrogenase (XDH) gene expression. Also disclosed are pharmaceutical compositions that include XDH RNAi agents and methods of use thereof. The XDH RNAi agents disclosed herein may be conjugated to targeting ligands to facilitate the delivery to cells, including to hepatocytes. Delivery of the XDH RNAi agents in vivo provides for inhibition of XDH gene expression. The RNAi agents can be used in methods of treatment of diseases, disorders, or symptoms mediated in part by XDH gene expression, such as gout and hyperuricemia.
    Type: Grant
    Filed: May 19, 2022
    Date of Patent: January 10, 2023
    Assignee: ARROWHEAD PHARMACEUTICALS, INC.
    Inventors: Anthony Nicholas, Tao Pei, Zhao Xu, Daniel Braas, Zhi-Ming Ding
  • Publication number: 20230002773
    Abstract: The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents, able to inhibit xanthine dehydrogenase (XDH) gene expression. Also disclosed are pharmaceutical compositions that include XDH RNAi agents and methods of use thereof. The XDH RNAi agents disclosed herein may be conjugated to targeting ligands to facilitate the delivery to cells, including to hepatocytes. Delivery of the XDH RNAi agents in vivo provides for inhibition of XDH gene expression. The RNAi agents can be used in methods of treatment of diseases, disorders, or symptoms mediated in part by XDH gene expression, such as gout and hyperuricemia.
    Type: Application
    Filed: May 19, 2022
    Publication date: January 5, 2023
    Inventors: Anthony NICHOLAS, Tao PEI, Zhao XU, Daniel BRAAS, Zhi-Ming DING
  • Patent number: 11463232
    Abstract: A system is provided for generating a time reference in duty-cycled wireless communications. The system includes at least one master module including a master transceiver adapted to transmit data packets. The system further includes at least one slave module including a slave transceiver adapted to receive the data packets. The slave module further includes a signal generator adapted to generate a clock signal with a period equal to the time interval of two data packets transmitted by the master module. Moreover, the slave module further includes a slave timer adapted to utilize the clock signal as a time reference in order to perform the sleep/wakeup control for the slave module.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: October 4, 2022
    Assignee: Stichting IMEC Nederland
    Inventors: Ming Ding, Yao-Hong Liu
  • Publication number: 20220255627
    Abstract: A silicon photonics based single wavelength 100 Gbit/s PAM4 DWDM transceiver in a pluggable form factor having a transmitter, said transmitter having: a DWDM laser source; a fiber array pigtail having a polarization maintaining fiber and an output single mode fiber; a silicon photonics modulator chip configured to optically connect to the DWDM laser source through the usage of the polarization maintaining fiber, a modulator driver chip connected to the silicon photonics modulator chip and an LC receptacle configured to optically connect to the silicon photonics modulator chip through the usage of the output single mode fiber. The disclosed transmitter may be further comprised of a reference loop within the silicon photonics modulator chip to allow for the utilization of a passive alignment approach for optically connected elements. The disclosed transceiver may be configured for use with C-band DWDM applications for utilization in applicable technologies, including 5G telecommunications.
    Type: Application
    Filed: January 27, 2022
    Publication date: August 11, 2022
    Inventors: Tongqing Wang, Xingyu Zhang, Dawei Zheng, Ming Ding, Yong Li
  • Patent number: 11398424
    Abstract: A semiconductor package structure includes a substrate. The substrate includes a first ground layer. The first ground layer has a body and a first tooth protruding from a side of the body. The first tooth has a first lateral side. The first lateral side of the first tooth is inclined relative to the side of the body in a top view of the first ground layer.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: July 26, 2022
    Assignee: ADVANCED SEMICONDUCTOR ENGINEERING, INC.
    Inventors: Jaw-Ming Ding, Ren-Hung Chou, Yi-Hung Lin
  • Publication number: 20220216879
    Abstract: Example embodiments relate to systems and methods for analog-to-digital signal conversion. One embodiment includes a system for analog-to-digital signal conversion. The system includes an analog input signal. The system also includes a digital-to-analog converter configured to generate a reference signal. Further, the system includes an amplifier configured to amplify an error signal that includes a difference between the analog input signal and the reference signal. Additionally, the system includes a level-crossing based sampling circuit that includes a first comparator configured to compare the error signal with respect to a first reference level, and a second comparator configured to compare the error signal with respect to a second reference level, thereby generating event-based reset signals corresponding to a plurality of sampling instances in order to reset the digital-to-analog converter.
    Type: Application
    Filed: December 28, 2021
    Publication date: July 7, 2022
    Inventors: Ming Ding, Martijn Timmermans, Pieter Harpe
  • Patent number: 11366952
    Abstract: The present invention relates generally to the technical field of integrated circuit mask design, and more particularly to a method, an apparatus and an electronic device for Hessian-Free photolithography mask optimization. The method includes steps: S1, inputting a design layout of a mask to be optimized; S2, positioning error monitoring points on the design layout of the mask to be optimized; S3, obtaining an optimization variable x of the mask to be optimized; S4, forming an objective function cost on the optimization variable x; and S5, optimizing the objective junction cost by a Hessian-Free-based conjugate gradient method, to obtain an optimization result of the mask to be optimized. Optimizing the objective function cost based on a Hessian-Free conjugate gradient method to obtain an optimization result of the mask to be optimized, which can greatly reduce the computation resources in the optimization process, make the optimization process simpler, feasible, and improve the optimization efficiency.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: June 21, 2022
    Assignee: SHENZHEN JINGYUAN INFORMATION TECHNOLOGY CO., LTD
    Inventor: Ming Ding
  • Publication number: 20220155916
    Abstract: The present application discloses a communication method, a terminal, a server, a communication system, a computer device and a medium. The communication method includes that a server establishes a connection and feeds back a display control in response to requests of a first terminal and a second terminal; then, the server feeds back function feedback information in response to a function request of the first terminal, and feeds back function feedback information in response to a menu request of the second terminal; and the servers presents multiple interface components and maintains and updates each interface component in response to management operation of a third user.
    Type: Application
    Filed: June 24, 2021
    Publication date: May 19, 2022
    Inventors: Ming DING, Li MA, Yang WU, Wanwan TANG, Dachuan WANG, Hong WANG, Guangyu SHAO, Chaozheng LIU
  • Patent number: 11281839
    Abstract: The present invention relates generally to the technical field of integrated circuit mask design, and more particularly to a method, an apparatus and an electronic device for photolithographic mask optimization of joint optimization of pattern and image. The method includes steps: inputting the main pattern; dividing edges of each main pattern into short edges, and regarding the short edges as a first variable for optimizing the main pattern; generating same or similar assistant feature sample points around same or similar main patterns, and regarding the assistant feature sample points as a second variable for optimizing the main pattern; and forming an objective function with the first variable and the second variable as optimization variables. The rules for generating assistant feature sample points around each main pattern are consistent, which are not limited to specific locations of the main pattern and ensures the consistency of final results for optimizing each main pattern.
    Type: Grant
    Filed: July 30, 2021
    Date of Patent: March 22, 2022
    Assignee: SHENZHEN JINGYUAN INFORMATION TECHNOLOGY CO., LTD
    Inventors: Ming Ding, Weijie Shi
  • Patent number: 11276194
    Abstract: Provided are a method and a device that can efficiently generate a training dataset.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: March 15, 2022
    Assignee: National University Corporation Nara Institute of Science and Technology
    Inventors: Keita Tomochika, Takuya Kiyokawa, Tsukasa Ogasawara, Jun Takamatsu, Ming Ding
  • Publication number: 20220027548
    Abstract: The present invention relates generally to the technical field of integrated circuit mask design, and more particularly to a method, an apparatus and an electronic device for photolithographic mask optimization of joint optimization of pattern and image. The method includes steps: inputting the main pattern; dividing edges of each main pattern into short edges, and regarding the short edges as a first variable for optimizing the main pattern; generating same or similar assistant feature sample points around same or similar main patterns, and regarding the assistant feature sample points as a second variable for optimizing the main pattern; and forming an objective function with the first variable and the second variable as optimization variables. The rules for generating assistant feature sample points around each main pattern are consistent, which are not limited to specific locations of the main pattern and ensures the consistency of final results for optimizing each main pattern.
    Type: Application
    Filed: July 30, 2021
    Publication date: January 27, 2022
    Applicant: SHENZHEN JINGYUAN INFORMATION TECHNOLOGY CO.,LTD
    Inventors: Ming DING, Weijie SHI
  • Publication number: 20220027547
    Abstract: The present invention relates generally to the technical field of integrated circuit mask design, and more particularly to a method, an apparatus and an electronic device for Hessian-Free photolithography mask optimization. The method includes steps: S1, inputting a design layout of a mask to be optimized; S2, positioning error monitoring points on the design layout of the mask to be optimized; S3, obtaining an optimization variable x of the mask to be optimized; S4, forming an objective function cost on the optimization variable x; and S5, optimizing the objective junction cost by a Hessian-Free-based conjugate gradient method, to obtain an optimization result of the mask to be optimized. Optimizing the objective function cost based on a Hessian-Free conjugate gradient method to obtain an optimization result of the mask to be optimized, which can greatly reduce the computation resources in the optimization process, make the optimization process simpler, feasible, and improve the optimization efficiency.
    Type: Application
    Filed: July 30, 2021
    Publication date: January 27, 2022
    Applicant: SHENZHEN JINGYUAN INFORMATION TECHNOLOGY CO.,LTD
    Inventor: Ming DING
  • Publication number: 20210346577
    Abstract: The present invention relates to a method for coating medical implants. In particular, the present invention relates to coating compositions comprising PDLLA, VEGF, chloroform, an organic solvent different from chloroform, preferably a carrier such as BSA and water for coating medical implants. Such coated medical implants show improved bone regeneration and ingrowth after implantation.
    Type: Application
    Filed: October 15, 2019
    Publication date: November 11, 2021
    Inventors: Chris Halling DREYER, Ming DING
  • Publication number: 20210301294
    Abstract: The present disclosure relates to RNAi agents, e.g., double stranded RNAi agents, able to inhibit patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene expression. Also disclosed are pharmaceutical compositions that include PNPLA3 RNAi agents and methods of use thereof. The PNPLA3 RNAi agents disclosed herein may be conjugated to targeting ligands to facilitate the delivery to cells, including to hepatocytes. Delivery of the PNPLA3 RNAi agents in vivo provides for inhibition of PNPLA3 gene expression. The RNAi agents can be used in methods of treatment of PNPLA3-related diseases and disorders, including non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), hepatic fibrosis, and alcoholic or non-alcoholic liver diseases, including cirrhosis.
    Type: Application
    Filed: March 26, 2021
    Publication date: September 30, 2021
    Inventors: Anthony Nicholas, Tao Pei, Zhao Xu, Casi Schienebeck, Zhi-Ming Ding
  • Publication number: 20210297840
    Abstract: This application provides a method and an apparatus for making an emergency call. The method includes: obtaining location information of UE; determining, based on the local information, whether the UE is located in a home country of an HPLMN of the UE; and when the UE is located in the home country of the HPLMN, if a predetermined condition is satisfied, initiating a VoWiFi emergency call by using an IMS APN of the HPLMN, where the predetermined condition includes: the UE has completed IMS registration, and a PLMN on which the UE camps includes no emergency APN. According to the method and apparatus for making an emergency call provided in this application, a VoWiFi emergency call success rate can be increased to some extent.
    Type: Application
    Filed: August 12, 2019
    Publication date: September 23, 2021
    Inventors: Ming DING, Fenghui DOU, Jie WU
  • Publication number: 20210257286
    Abstract: A semiconductor package structure includes a substrate. The substrate includes a first ground layer. The first ground layer has a body and a first tooth protruding from a side of the body. The first tooth has a first lateral side. The first lateral side of the first tooth is inclined relative to the side of the body in a top view of the first ground layer.
    Type: Application
    Filed: February 18, 2020
    Publication date: August 19, 2021
    Applicant: Advanced Semiconductor Engineering, Inc.
    Inventors: Jaw-Ming DING, Ren-Hung CHOU, Yi-Hung LIN
  • Publication number: 20210235223
    Abstract: The present disclosure describes how a master beacon having a known UUID can be used to capture beacons within its range and superimpose a systematic address scheme on those beacons. The superimposed address scheme can then be used as a proxy for the individual beacons when developing applications that make use of the beacons. A master beacon automatically detects each beacon in a plurality of beacons and, for a set of beacons in the plurality of beacons, automatically changes either the first profile identifier or the second profile identifier for each beacon in the set of beacons. The change is such that the first profile identifier or the second profile identifier is identical for each beacon in the set of beacons and is also associated with the master beacon.
    Type: Application
    Filed: March 19, 2021
    Publication date: July 29, 2021
    Inventors: Aaron Lyon PHILLIPS-LUBIMIV, Jay FALLAH, Ming DING, Samson Grant KIRK-KOFFI
  • Publication number: 20210218543
    Abstract: A system is provided for generating a time reference in duty-cycled wireless communications. The system includes at least one master module including a master transceiver adapted to transmit data packets. The system further includes at least one slave module including a slave transceiver adapted to receive the data packets. The slave module further includes a signal generator adapted to generate a clock signal with a period equal to the time interval of two data packets transmitted by the master module. Moreover, the slave module further includes a slave timer adapted to utilize the clock signal as a time reference in order to perform the sleep/wakeup control for the slave module.
    Type: Application
    Filed: January 5, 2021
    Publication date: July 15, 2021
    Inventors: Ming Ding, Yao-Hong Liu
  • Patent number: 10992266
    Abstract: A power amplifier circuit includes a first transistor, a second transistor and a bias circuit. The first transistor has a base configured to receive a first signal. The second transistor has an emitter connecting to a collector of the first transistor and a collector configured to output a second signal. The bias circuit is coupled to the first transistor and the second transistor. The bias circuit is configured to provide a direct current (DC) voltage at the collector of the second transistor about twice a DC voltage at the collector of the first transistor. The bias circuit is configured to provide an alternating current (AC) or radio frequency (RF) voltage at the collector of the second transistor about twice an AC or RF voltage at the collector of the first transistor.
    Type: Grant
    Filed: March 26, 2019
    Date of Patent: April 27, 2021
    Assignee: ADVANCED SEMICONDUCTOR ENGINEERING, INC.
    Inventor: Jaw-Ming Ding
  • Patent number: 10979853
    Abstract: The present disclosure describes how a master beacon having a known QUID can be used to capture beacons within its range and superimpose a systematic address scheme on those beacons. The superimposed address scheme can then be used as a proxy for the individual beacons when developing applications that make use of the beacons. A master beacon automatically detects each beacon in a plurality of beacons and, for a set of beacons in the plurality of beacons, automatically changes either the first profile identifier or the second profile identifier for each beacon in the set of beacons. The change is such that the first profile identifier or the second profile identifier is identical for each beacon in the set of beacons and is also associated with the master beacon.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: April 13, 2021
    Assignee: AP1 INC.
    Inventors: Aaron Lyon Phillips-Lubimiv, Jay Fallah, Ming Ding, Samson Grant Kirk-Koffi