Patents by Inventor Ming-Fan Law

Ming-Fan Law has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8308722
    Abstract: A hollow coaxial cable adapted for conduction of radio frequency (RF) energy, particularly microwave energy, has a proximal end and a distal end and comprises coaxial inner and outer conductors extending substantially the entire length of the cable from the proximal end to a distal end portion of the cable with a dielectric medium disposed between the inner and outer conductors. The inner conductor comprises an elongated electrically conductive tubular member having a hollow, axially extending lumen, and the outer conductor comprises an elongated electrically conductive tubular member disposed in a substantially coaxial relationship over at least a portion of the inner conductor. An ablating member which delivers radio frequency energy, particularly microwave energy, to body tissue is disposed at a distal end portion of the cable.
    Type: Grant
    Filed: July 23, 2007
    Date of Patent: November 13, 2012
    Assignee: MedWaves, Inc.
    Inventors: Theodore C. Ormsby, George L. Leung, Gwo Jenn Shen, Peter Chu, Ming Fan Law
  • Patent number: 8152799
    Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.
    Type: Grant
    Filed: September 8, 2010
    Date of Patent: April 10, 2012
    Assignee: Medwaves, Inc.
    Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
  • Publication number: 20110009858
    Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.
    Type: Application
    Filed: September 8, 2010
    Publication date: January 13, 2011
    Applicant: MEDWAVES, INC.
    Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
  • Patent number: 7815637
    Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.
    Type: Grant
    Filed: February 22, 2006
    Date of Patent: October 19, 2010
    Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
  • Patent number: 7594913
    Abstract: A radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency (“RF”) generator for selectively generating a high frequency RF energy signal in a deployable catheter having an RF transmission line, an RF antenna mounted on the distal portion of the catheter, and a temperature sensor also mounted on a distal portion of the catheter for detecting temperature adjacent an ablation site. A control system adjusts the RF energy signal so that the detected temperature is at or close to a selected temperature setting or within a selected temperature range.
    Type: Grant
    Filed: June 30, 2006
    Date of Patent: September 29, 2009
    Assignee: Medwaves, Inc.
    Inventors: Theodore C. Ormsby, George L. Leung, Gwo Jenn Shen, Peter Chu, Ming Fan Law
  • Publication number: 20090082762
    Abstract: A radio frequency energy transmission device comprises a hollow coaxial electrically conductive cable adapted for conduction of radio frequency (RF) energy, particularly microwave energy, for the ablation of biological tissue. The hollow cable has a proximal end and a distal end and comprises coaxial inner and outer conductors extending substantially the entire length of the cable from the proximal end to a distal end portion of the cable. The inner conductor comprises an elongated electrically conductive tubular member having a hollow, axially extending lumen, and the outer conductor comprises an elongated electrically conductive tubular member disposed in a substantially coaxial relationship over at least a portion of the inner conductor. Dielectricity to impede conduction between the inner and outer conductors is introduced with a vacuum or dielectric medium disposed between the inner and outer conductors.
    Type: Application
    Filed: September 20, 2007
    Publication date: March 26, 2009
    Inventors: Theodore C. Ormsby, George L. Leung, Ming Fan Law
  • Publication number: 20060287649
    Abstract: A radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency (“RF”) generator for selectively generating a high frequency RF energy signal in a deployable catheter having an RF transmission line, an RF antenna mounted on the distal portion of the catheter, and a temperature sensor also mounted on a distal portion of the catheter for detecting temperature adjacent an ablation site. A control system adjusts the RF energy signal so that the detected temperature is at or close to a selected temperature setting or within a selected temperature range.
    Type: Application
    Filed: June 30, 2006
    Publication date: December 21, 2006
    Inventors: Theodore Ormsby, George Leung, Gwo Shen, Peter Chu, Ming Fan Law
  • Patent number: 7070595
    Abstract: A method for biological tissue ablation includes shaping a shapeable RF antenna to accommodate the contour of a body vessel adjacent a biological tissue load; generating a train of radio frequency (RF) energy pulses at an output frequency for transmission in a transmission line to the shapeable RF antenna adjacent the biological tissue load; sensing a reflected signal and a forward signal of the RF energy pulses; and adjusting output frequency of the RF energy pulses to effect a substantial match of transmission line impedance with shapeable RF antenna and biological tissue load impedance.
    Type: Grant
    Filed: August 8, 2003
    Date of Patent: July 4, 2006
    Assignee: Medwaves, Inc.
    Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
  • Publication number: 20060142752
    Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.
    Type: Application
    Filed: February 22, 2006
    Publication date: June 29, 2006
    Inventors: Theodore Ormsby, Ming-Fan Law, George Leung
  • Patent number: 7004938
    Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.
    Type: Grant
    Filed: November 27, 2002
    Date of Patent: February 28, 2006
    Assignee: MedWaves, Inc.
    Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
  • Patent number: 6941953
    Abstract: A preformed catheter set for production of linear ablation lines in the left and right atrium for treatment of atrial fibrillation includes at least a first catheter including a pre-shaped distal segment having a distal linear ablation antenna and a U-shaped curve portion proximal to the distal linear ablation antenna.
    Type: Grant
    Filed: February 6, 2004
    Date of Patent: September 13, 2005
    Assignee: Medwaves, Inc.
    Inventors: Gregory K. Feld, Theodore C. Ormsby, Ming-Fan Law, George L. Leung
  • Publication number: 20040167510
    Abstract: A preformed catheter set for production of linear ablation lines in the left and right atrium for treatment of atrial fibrillation includes at least a first catheter including a pre-shaped distal segment having a distal linear ablation antenna and a U-shaped curve portion proximal to the distal linear ablation antenna.
    Type: Application
    Filed: February 6, 2004
    Publication date: August 26, 2004
    Applicant: Medwaves, Inc.
    Inventors: Gregory K. Feld, Theodore C. Ormsby, Ming-Fan Law, George L. Leung
  • Publication number: 20040106917
    Abstract: An improved radio-frequency based catheter system and method for ablating biological tissues within the body vessel of a patient comprises a radio-frequency (“RF”) generator for selectively generating high frequency energy in a deployable catheter having a RF co-axial transmission line with a hollow lumen, a RF antenna mounted on the distal portion of the catheter, and steering control lines in the lumen of the transmission line for steering catheter while being inserted into the body vessel and for deflecting the RF antenna to accommodate the contour of the body vessel where tissue ablation is needed. The RF generator having variable output frequency is adapted to generate and communicate RF energy to the RF antenna that minimizes reflected energy from the antenna-tissue interface. In application, the RF antenna establishes line of contact with the body vessel conformable to its internal contour to prescribe the precise tissue ablation pathway despite body vessel movements.
    Type: Application
    Filed: August 8, 2003
    Publication date: June 3, 2004
    Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
  • Patent number: 6663625
    Abstract: An improved radio-frequency catheter system for ablating biological tissues of a body vessel in a patient including a catheter, a deployable antenna guide disposed at the distal portion of the catheter and a radio-frequency (“RF”) antenna mounted on the antenna guide. The RF antenna includes a axial passageway to accommodate the antenna guide, and is adapted to receive and transmit RF energy for tissue ablation. Upon deployment, the antenna guide acquires a loop configuration which establishes line contact with the body vessel conformable to its internal contour to prescribe the precise and affixed tissue ablation pathway despite body vessel movements. The RF antenna is carried by the antenna guide to be deployed along the established tissue ablation pathway. Alignment of the loop with the desired tissue ablation pathway is facilitated with the use of radio-opaque markers and intracardiac electrodes mounted along the antenna guide.
    Type: Grant
    Filed: December 11, 1999
    Date of Patent: December 16, 2003
    Inventors: Theodore C. Ormsby, George L. Leung, Ming-Fan Law
  • Publication number: 20030114844
    Abstract: A RF catheter system includes a catheter with a proximal portion, a distal portion having a distal end and a lumen extending from the proximal portion to the distal portion. Inner and outer coaxially aligned conductors extend within the catheter and are coaxial with the lumen. A deflectable catheter guide is disposed within the catheter lumen and extends proximally within the catheter lumen and terminates distally of the distal end of the catheter to define a biological ablation pathway. A radio-frequency antenna is disposed at the distal portion of the catheter and is in electrical communication with the inner and outer coaxially aligned conductors. The radio-frequency antenna is adaptable to receive and transmit radio-frequency energy for ablating biological tissue along the ablation pathway.
    Type: Application
    Filed: November 27, 2002
    Publication date: June 19, 2003
    Applicant: Medwaves, Inc.
    Inventors: Theodore C. Ormsby, Ming-Fan Law, George L. Leung
  • Patent number: 6190382
    Abstract: An improved radio-frequency catheter system for ablating biological tissues of a body vessel in a patient including a catheter, a deployable antenna guide disposed at the distal portion of the catheter and a radio-frequency (“RF”) antenna mounted on the antenna guide. The RF antenna includes a helical coil which defines an axial passageway to accommodate the antenna guide, and is adapted to receive and transmit RF energy for tissue ablation. Upon deployment, the antenna guide acquires a loop configuration which establishes line contact with the body vessel conformable to its internal contour to prescribe the precise and affixed tissue ablation pathway despite body vessel movements. The RF antenna is carried by the antenna guide to be deployed along the established tissue ablation pathway. Alignment of the loop with the desired tissue ablation pathway is facilitated with the use of radio-opaque markers and intracardiac electrodes mounted along the antenna guide.
    Type: Grant
    Filed: December 14, 1998
    Date of Patent: February 20, 2001
    Assignee: Medwaves, Inc.
    Inventors: Theodore C. Ormsby, George L. Leung, Ming-Fan Law
  • Patent number: 4419446
    Abstract: A novel method and composition are provided for the replication and expression of exogenous genes in eukaryotic cells. A segment of a papilloma virus genome capable of extrachromosomal replication is linked to the foreign gene(s) using recombinant DNA techniques to provide a biologically functional replicon with a desired phenotypical property. The replicon is inserted into a eukaryotic cell by transformation, and the isolation of transformant provides cells for replication and expression of the DNA molecules present in the modified plasmid. The transforming region of the bovine papilloma virus provides a unique vector in that it provides both the capability of autonomous extrachromosomal replication but also the malignant transformed phenotype. Thus, genes which of themselves provide no selectable phenotypical property can be conveniently and efficiently introduced into eukaryotic cells and the transformants selected.
    Type: Grant
    Filed: December 31, 1980
    Date of Patent: December 6, 1983
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Peter M. Howley, Nava Sarver, Ming-Fan Law