Patents by Inventor Mingqi Zhao

Mingqi Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200054838
    Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.
    Type: Application
    Filed: October 25, 2019
    Publication date: February 20, 2020
    Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
  • Publication number: 20200054840
    Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.
    Type: Application
    Filed: October 25, 2019
    Publication date: February 20, 2020
    Inventors: Lorin Olson, Vaclav Vojan, Juergen E. Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
  • Patent number: 10500348
    Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.
    Type: Grant
    Filed: December 4, 2015
    Date of Patent: December 10, 2019
    Assignee: Janssen Biotech, Inc.
    Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
  • Patent number: 10485931
    Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: November 26, 2019
    Assignee: Janssen Biotech, Inc.
    Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
  • Publication number: 20160089503
    Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.
    Type: Application
    Filed: December 4, 2015
    Publication date: March 31, 2016
    Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
  • Publication number: 20160058955
    Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.
    Type: Application
    Filed: November 12, 2015
    Publication date: March 3, 2016
    Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
  • Patent number: 9233213
    Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: January 12, 2016
    Assignee: Janssen Biotech, Inc.
    Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
  • Patent number: 9216256
    Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: December 22, 2015
    Assignee: JANSSEN BIOTECH, INC.
    Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
  • Publication number: 20130204229
    Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.
    Type: Application
    Filed: March 15, 2013
    Publication date: August 8, 2013
    Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
  • Patent number: 7944366
    Abstract: Systems and methods of detecting occlusions and fluid-loss conditions (e.g., disconnects and/or leakages) in an infusion pump are discussed. For example, electrokinetic infusion pumps may develop an occlusion in the fluid flow path, which can disrupt control of fluid dispersed from the pump. As well, an infusion set disconnect can also result in a fluid-loss that can be disruptive. Such disruptions can be troublesome to systems that control the infusion pump, such as closed loop controllers. Accordingly, systems and methods described herein can be used to detect such occlusions and fluid-loss conditions during infusion pump operation. For example, a position sensor can be used to monitor fluid flow from the infusion pump, with the measurement being compared with an expected value to detect an occlusion or fluid-loss condition. Other algorithms for utilizing the position sensor are also described.
    Type: Grant
    Filed: September 18, 2006
    Date of Patent: May 17, 2011
    Assignee: Lifescan, Inc.
    Inventors: Peter Krulevitch, Sebastian Bohm, Mingqi Zhao, Deon Anex
  • Publication number: 20110092915
    Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 21, 2011
    Applicant: Centocor
    Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
  • Publication number: 20100300897
    Abstract: A flexible indwelling electrochemical-based biosensor includes an elongated framework and an integrated electrochemical-based biosensor. The elongated framework is formed of an electrically conductive flexible material (e.g., a Nitinol) with a body portion, a sharp head, a distal end and a proximal end. The integrated electrochemical-based biosensor (such as an electrochemical-based glucose sensor) is integrated with the elongated framework in that the biosensor has a sensing element that is disposed over the body portion or sharp head of the elongated framework and a portion of the elongated framework is configured as an electrode component that electrically cooperates with the sensing element. The electrode component can, for example, be configured to electrically cooperate as a working electrode, counter electrode, reference electrode or combined reference/counter electrode of the sensing element.
    Type: Application
    Filed: May 28, 2009
    Publication date: December 2, 2010
    Applicant: LifeScan, Inc.
    Inventors: Donna SAVAGE, Peter Krulevitch, Mingqi Zhao
  • Patent number: 7666287
    Abstract: A method for preparing an electrokinetic element is provided and generally includes providing a porous membrane adapted for use in an electrokinetic pump and encapsulating the porous membrane within a polymer substrate to yield an electrokinetic element base member having the porous membrane encapsulated by the polymer. In one embodiment, the method can include laminating the porous membrane between opposed sheets of a polymer before the step of encapsulating. The method can also include cutting the electrokinetic element base member into a plurality of slices and assembling an electrokinetic infusion pump by inserting a slice into a chamber of the pump.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: February 23, 2010
    Assignee: Lifescan, Inc.
    Inventors: Mingqi Zhao, Mark Huang, Stan Thomas, Peter Krulevitch
  • Patent number: 7654127
    Abstract: The present application is directed to systems and methods associated with infusion pumps, which can optionally utilize an electrokinetic driving mechanism. Infusion pumps, including electrokinetically-driven pumps, are discussed, along with schemes for controlling their operation. As well, systems and methods of detecting malfunctions in infusion pumps are discussed. Any number of malfunctions can be detected including the presence of occlusions and/or leaks. In some instances, a measurement associated with some aspect of electrokinetic phenomena (e.g., an electrode measurement such as voltage or current) is compared with one or more sample values, the comparison allowing an indication of pump malfunction to be determined. A variety of such measurements and comparison techniques are discussed in the present disclosure.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: February 2, 2010
    Assignee: Lifescan, Inc.
    Inventors: Peter Krulevitch, Mingqi Zhao, Sebastian Bohm, Deon Anex, Michael Gearhart
  • Publication number: 20090247982
    Abstract: A medical device pump with a housing with a compartment for removably receiving a cartridge containing a therapeutic agent, a conduit configured to operatively provide a fluid flow path for therapeutic agent to exit from the cartridge, a user activated delivery button, a trigger mechanism, and a mechanical pump mechanism. The trigger mechanism, user activated delivery button and mechanical pump mechanism of the medical device pump are configured such that the trigger mechanism is activated by a user fully activating the user activated delivery button. Moreover, such full activation generates mechanical power employed by, and sufficient for, the mechanical pump mechanism to pump a predetermined volume of therapeutic agent from the cartridge and through the fluid flow path.
    Type: Application
    Filed: March 19, 2009
    Publication date: October 1, 2009
    Applicant: LifeScan Inc.
    Inventors: Peter Krulevitch, Robert Wilk, Sean O'Connor, Mingqi Zhao, Zara Sieh, Donna Savage
  • Publication number: 20080235948
    Abstract: The invention provides related apparatus and methods of making an integrated electrospray tip by depositing ionic and/or electronic conductor materials onto a planar substrate. The invention also features methods of forming an electrospray apparatus comprising coupling a first planar substrate to the surface of a second planar substrate, wherein a surface on at least one of the substrates includes one or more microfluidic channels and/or reservoirs which are at least partially or totally enclosed therebetween. The conductive regions of the apparatus do not intersect the microfluidic channels within other portions of the apparatus provided preferably. The invention further provides related apparatus and methods for manufacturing and using microfluidic devices with integrated electrodes for electrospray ionization.
    Type: Application
    Filed: March 26, 2008
    Publication date: October 2, 2008
    Applicant: Predicant Biosciences, Inc.
    Inventors: Luc Bousse, Mingqi Zhao
  • Publication number: 20080149268
    Abstract: A method for preparing an electrokinetic element is provided and generally includes providing a porous membrane adapted for use in an electrokinetic pump and encapsulating the porous membrane within a polymer substrate to yield an electrokinetic element base member having the porous membrane encapsulated by the polymer. In one embodiment, the method can include laminating the porous membrane between opposed sheets of a polymer before the step of encapsulating. The method can also include cutting the electrokinetic element base member into a plurality of slices and assembling an electrokinetic infusion pump by inserting a slice into a chamber of the pump.
    Type: Application
    Filed: December 21, 2006
    Publication date: June 26, 2008
    Applicant: LifeScan, Inc.
    Inventors: Mingqi Zhao, Mark Huang, Stan Thomas, Peter Krulevitch
  • Publication number: 20080154187
    Abstract: The present application is directed to systems and methods associated with infusion pumps, which can optionally utilize an electrokinetic driving mechanism. Infusion pumps, including electrokinetically-driven pumps, are discussed, along with schemes for controlling their operation. As well, systems and methods of detecting malfunctions in infusion pumps are discussed. Any number of malfunctions can be detected including the presence of occlusions and/or leaks. In some instances, a measurement associated with some aspect of electrokinetic phenomena (e.g., an electrode measurement such as voltage or current) is compared with one or more sample values, the comparison allowing an indication of pump malfunction to be determined. A variety of such measurements and comparison techniques are discussed in the present disclosure.
    Type: Application
    Filed: December 21, 2006
    Publication date: June 26, 2008
    Applicant: LifeScan, Inc.
    Inventors: Peter Krulevitch, Mingqi Zhao, Sebastian Bohm, Deon Anex, Michael Gearhart
  • Patent number: 7391020
    Abstract: The invention provides related apparatus and methods of making an integrated electrospray tip by depositing ionic and/or electronic conductor materials onto a planar substrate. The invention also features methods of forming an electrospray apparatus comprising coupling a first planar substrate to the surface of a second planar substrate, wherein a surface on at least one of the substrates includes one or more microfluidic channels and/or reservoirs which are at least partially or totally enclosed therebetween. The conductive regions of the apparatus do not intersect the microfluidic channels within other portions of the apparatus provided preferably. The invention further provides related apparatus and methods for manufacturing and using microfluidic devices with integrated electrodes for electrospray ionization.
    Type: Grant
    Filed: November 3, 2006
    Date of Patent: June 24, 2008
    Inventors: Luc Bousse, Mingqi Zhao
  • Publication number: 20070093752
    Abstract: An infusion pump (e.g., an electrokinetic infusion pump) includes an infusion pump module and an engine that can drive a moveable piston non-mechanically. In addition, the infusion pump module includes a position detector configured for sensing a dispensing state of the infusion pump module. Such information can be utilized in a control scheme to control fluid displacement within and out of the pump. Descriptions of different types of position detectors, such as magnetic sensors (e.g., an anisotropic magnetic resistive sensor), and their implementation in detecting infusion pump fluid displacement are described.
    Type: Application
    Filed: September 18, 2006
    Publication date: April 26, 2007
    Applicant: LifeScan, Inc.
    Inventors: Mingqi Zhao, Peter Krulevitch