Patents by Inventor Mingqi Zhao
Mingqi Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230263972Abstract: Various exemplary drug delivery devices with on-board drug destruction, drug products utilizing the same, and methods of using drug delivery devices with on-board drug destruction are provided. In general, a nasal drug delivery device configured to dispense a drug therefrom into a nose includes a destruction mechanism configured to destroy drug contained in the drug delivery device. The destruction mechanism can be configured to destroy the drug before a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug contained in the drug delivery device. Alternatively or in addition, the destruction mechanism can be configured to destroy the drug after a first actuation of the drug delivery device to deliver the drug therefrom such that the destruction mechanism destroys substantially all of the drug remaining in the drug delivery device.Type: ApplicationFiled: September 1, 2021Publication date: August 24, 2023Inventors: Emma Louise HUBERT, Monica A. KAPIL, MingQi ZHAO, Steven M. VESOLE, Ian SCRIMGEOUR, David RAMOS, Jaskaran SINGH, Jingli WANG, David KALIKHMAN, Shagun POPLI, Peter KRULEVITCH, Hong YAN, Michael A. BARATTA, Whitney PHILLIPS, Francesco N. ALBERTINI, Michael CANNAMELA
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Publication number: 20230218833Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.Type: ApplicationFiled: March 8, 2023Publication date: July 13, 2023Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
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Patent number: 11633546Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.Type: GrantFiled: October 25, 2019Date of Patent: April 25, 2023Assignee: Janssen Biotech, Inc.Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
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Publication number: 20230090397Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.Type: ApplicationFiled: November 29, 2022Publication date: March 23, 2023Inventors: Lorin Olson, Vaclav Vojan, Juergen E. Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
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Publication number: 20230022239Abstract: Various exemplary liquid drug pumps with a flexible drug reservoir are provided. In general, a pump includes a flexible reservoir configured to contain a liquid drug therein for delivery to a patient wearing the pump. The reservoir is configured to be filled with the drug from a drug storage container, which can either be external to the pump or disposed within the pump.Type: ApplicationFiled: December 2, 2020Publication date: January 26, 2023Inventors: Michael CANNAMELA, Peter KRULEVITCH, MingQi ZHAO, Brandon MCKENZIE
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Patent number: 11541190Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.Type: GrantFiled: October 25, 2019Date of Patent: January 3, 2023Assignee: Janssen Biotech, Inc.Inventors: Lorin Olson, Vaclav Vojan, Juergen E. Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
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Publication number: 20200054840Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.Type: ApplicationFiled: October 25, 2019Publication date: February 20, 2020Inventors: Lorin Olson, Vaclav Vojan, Juergen E. Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
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Publication number: 20200054838Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.Type: ApplicationFiled: October 25, 2019Publication date: February 20, 2020Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
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Patent number: 10500348Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.Type: GrantFiled: December 4, 2015Date of Patent: December 10, 2019Assignee: Janssen Biotech, Inc.Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
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Patent number: 10485931Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.Type: GrantFiled: November 12, 2015Date of Patent: November 26, 2019Assignee: Janssen Biotech, Inc.Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
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Publication number: 20160089503Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.Type: ApplicationFiled: December 4, 2015Publication date: March 31, 2016Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
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Publication number: 20160058955Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.Type: ApplicationFiled: November 12, 2015Publication date: March 3, 2016Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
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Patent number: 9233213Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.Type: GrantFiled: March 15, 2013Date of Patent: January 12, 2016Assignee: Janssen Biotech, Inc.Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
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Patent number: 9216256Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.Type: GrantFiled: October 15, 2010Date of Patent: December 22, 2015Assignee: JANSSEN BIOTECH, INC.Inventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
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Publication number: 20130204229Abstract: A device configured to administer a medication can comprise a lower housing that includes a housing latch. The device can further comprise a needle guard that is movable relative to the lower housing along a first direction from a first position to a second position so as to expose a needle, and an upper housing supported relative to the lower housing. The upper housing can be configured to move with respect to the lower housing along a second direction from a pre-use position to a dispensed position. The housing latch can releasably interfere with the upper housing when the upper housing is in the pre-use position so as to prevent the upper housing from moving toward the dispensed position, and the movement of the needle guard toward the second position, causes the interference to be removed, thereby allowing the upper housing to move toward the second position.Type: ApplicationFiled: March 15, 2013Publication date: August 8, 2013Inventors: Lorin Olson, Vaclav Vojan, Juergen Ernst Pfrang, Peter Krulevitch, Jingli Wang, Nicholas Foley, Mingqi Zhao, Paul Tashjian
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Patent number: 7944366Abstract: Systems and methods of detecting occlusions and fluid-loss conditions (e.g., disconnects and/or leakages) in an infusion pump are discussed. For example, electrokinetic infusion pumps may develop an occlusion in the fluid flow path, which can disrupt control of fluid dispersed from the pump. As well, an infusion set disconnect can also result in a fluid-loss that can be disruptive. Such disruptions can be troublesome to systems that control the infusion pump, such as closed loop controllers. Accordingly, systems and methods described herein can be used to detect such occlusions and fluid-loss conditions during infusion pump operation. For example, a position sensor can be used to monitor fluid flow from the infusion pump, with the measurement being compared with an expected value to detect an occlusion or fluid-loss condition. Other algorithms for utilizing the position sensor are also described.Type: GrantFiled: September 18, 2006Date of Patent: May 17, 2011Assignee: Lifescan, Inc.Inventors: Peter Krulevitch, Sebastian Bohm, Mingqi Zhao, Deon Anex
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Publication number: 20110092915Abstract: Disclosed is a device for the parenteral delivery of a medication, such as a drug. The device includes upper and lower housings in which the upper housing is configured to move relative to the lower housing as a result of application of an external force to permit the user of the device to control the rate at which the drug is administered.Type: ApplicationFiled: October 15, 2010Publication date: April 21, 2011Applicant: CentocorInventors: Lorin P. Olson, Peter Krulevitch, James Glencross, Jingli Wang, Nicholas Foley, Mingqi Zhao
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Publication number: 20100300897Abstract: A flexible indwelling electrochemical-based biosensor includes an elongated framework and an integrated electrochemical-based biosensor. The elongated framework is formed of an electrically conductive flexible material (e.g., a Nitinol) with a body portion, a sharp head, a distal end and a proximal end. The integrated electrochemical-based biosensor (such as an electrochemical-based glucose sensor) is integrated with the elongated framework in that the biosensor has a sensing element that is disposed over the body portion or sharp head of the elongated framework and a portion of the elongated framework is configured as an electrode component that electrically cooperates with the sensing element. The electrode component can, for example, be configured to electrically cooperate as a working electrode, counter electrode, reference electrode or combined reference/counter electrode of the sensing element.Type: ApplicationFiled: May 28, 2009Publication date: December 2, 2010Applicant: LifeScan, Inc.Inventors: Donna SAVAGE, Peter Krulevitch, Mingqi Zhao
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Patent number: 7666287Abstract: A method for preparing an electrokinetic element is provided and generally includes providing a porous membrane adapted for use in an electrokinetic pump and encapsulating the porous membrane within a polymer substrate to yield an electrokinetic element base member having the porous membrane encapsulated by the polymer. In one embodiment, the method can include laminating the porous membrane between opposed sheets of a polymer before the step of encapsulating. The method can also include cutting the electrokinetic element base member into a plurality of slices and assembling an electrokinetic infusion pump by inserting a slice into a chamber of the pump.Type: GrantFiled: December 21, 2006Date of Patent: February 23, 2010Assignee: Lifescan, Inc.Inventors: Mingqi Zhao, Mark Huang, Stan Thomas, Peter Krulevitch
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Patent number: 7654127Abstract: The present application is directed to systems and methods associated with infusion pumps, which can optionally utilize an electrokinetic driving mechanism. Infusion pumps, including electrokinetically-driven pumps, are discussed, along with schemes for controlling their operation. As well, systems and methods of detecting malfunctions in infusion pumps are discussed. Any number of malfunctions can be detected including the presence of occlusions and/or leaks. In some instances, a measurement associated with some aspect of electrokinetic phenomena (e.g., an electrode measurement such as voltage or current) is compared with one or more sample values, the comparison allowing an indication of pump malfunction to be determined. A variety of such measurements and comparison techniques are discussed in the present disclosure.Type: GrantFiled: December 21, 2006Date of Patent: February 2, 2010Assignee: Lifescan, Inc.Inventors: Peter Krulevitch, Mingqi Zhao, Sebastian Bohm, Deon Anex, Michael Gearhart