Patents by Inventor Minhong Yan

Minhong Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-EPHRINB2 ANTIBODIES AND METHODS USING SAME
    Publication number: 20090214564
    Abstract: The invention provides anti-EphrinB2 antibodies, and compositions comprising and methods of using these antibodies.
    Type: Application
    Filed: January 19, 2007
    Publication date: August 27, 2009
    Applicant: Genentech, Inc.
    Inventors: Yan Wu, Minhong Yan
  • Novel tumor necrosis factor receptor homologs and nucleic acids encoding the same
    Publication number: 20080305996
    Abstract: The present invention is directed to novel polypeptides having homology to members of the tumor necrosis factor receptor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: August 29, 2006
    Publication date: December 11, 2008
    Inventors: Audrey Goddard, James Pan, Minhong Yan
  • ANTI-DLL4 ANTIBODIES AND METHODS USING SAME
    Publication number: 20080175847
    Abstract: The invention provides anti-DLL4 antibodies, and compositions comprising and methods of using these antibodies.
    Type: Application
    Filed: June 6, 2007
    Publication date: July 24, 2008
    Applicant: Genentech, Inc.
    Inventors: Minhong Yan, Yan Wu
  • TACI ANTIBODIES AND USES THEREOF
    Publication number: 20080171036
    Abstract: TACI receptor antibodies are provided. The TACI antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the TACI antibodies are also provided.
    Type: Application
    Filed: August 20, 2007
    Publication date: July 17, 2008
    Inventors: Anan Chuntharapai, Iqbal Grewal, Kyung Jin Kim, Minhong Yan
  • COMPOSITIONS AND METHODS FOR MODULATING VASCULAR DEVELOPMENT
    Publication number: 20080014196
    Abstract: The present invention provides methods of using a DLL4 modulator to modulate vascular development. Furthermore, methods of treatment using DLL4 modulators, such as DLL4 antagonists, are provided.
    Type: Application
    Filed: June 6, 2007
    Publication date: January 17, 2008
    Applicant: Genentech, Inc.
    Inventor: Minhong Yan
  • Nucleic acids encoding a tumor necrosis factor homolog
    Patent number: 7198913
    Abstract: The present invention is directed to novel polypeptides having homology to members of the tumor necrosis factor receptor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: April 3, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, James Pan, Minhong Yan
  • Uses of agonists and antagonists to modulate activity of TNF-related molecules
    Publication number: 20060073146
    Abstract: Methods of using one or more agonists or antagonists to modulate activity of the members of the TNF and TNFR families referred to as TALL-1, APRIL, TACI, and BCMA are provided. The methods include in vitro, in situ, and/or in vivo diagnosis and/or treatment of mammalian cells or pathological conditions associated with TALL-1, APRIL, TACI, or BCMA, using one or more agonist or antagonist molecules. The methods of treatment disclosed by the invention include methods of treating immune related diseases and cancer.
    Type: Application
    Filed: February 28, 2005
    Publication date: April 6, 2006
    Inventors: Avi Ashkenazi, Kelly Dodge, Iqbal Grewal, Kyung Kim, Scot Marsters, Robert Pitti, Minhong Yan
  • Taci and br3 polypeptides and uses thereof
    Publication number: 20050070689
    Abstract: Novel, receptors, referred to herein as “TACIs” and “BR3”, agonists and antagonists thereof, and method of using TACIs and BR3, as well as agonists and antagonists thereof, to modulate, for example, activity of tumor necrosis factor (TNF) and TNFR-related molecules, including members of the TNF and TNFR families referred to as TALL-1, APRIL, TACI, and BCMA, are provided. Methods for in vitro, in situ, and/or in vivo diagnosis and/or treatment of mammalian cells or pathological conditions associated with such TNF and TNFR-related molecules are further provided.
    Type: Application
    Filed: July 24, 2002
    Publication date: March 31, 2005
    Applicant: GENENTECH, INC.
    Inventors: Vishva Dixit, Iqbal Grewal, John Ridgway, Minhong Yan
  • TACI antibodies and uses thereof
    Publication number: 20050043516
    Abstract: TACI receptor antibodies are provided. The TACI antibodies may be included in pharmaceutical compositions, articles of manufacture, or kits. Methods of treatment and diagnosis using the TACI antibodies are also provided.
    Type: Application
    Filed: July 25, 2003
    Publication date: February 24, 2005
    Applicant: Genentech, Inc.
    Inventors: Anan Chuntharapai, Iqbal Grewal, Kyung Kim, Minhong Yan
  • Amplification-based cloning method
    Publication number: 20030165979
    Abstract: The invention provides a method for isolating a nucleic acid molecule of interest from a nucleic acid library, which involves generating multiple copies of a nucleic acid molecule of interest present in the library and an enrichment step to remove template nucleic acid molecules. The method of invention has greater efficiency and possesses superior features compared to conventional cloning methods, and is capable of use for identifying and isolating known and novel nucleic acid molecules.
    Type: Application
    Filed: April 14, 2003
    Publication date: September 4, 2003
    Applicant: Genentech, Inc.
    Inventors: Clarissa J. Chui, J. Christopher Grimaldi, Sean Milton, Minhong Yan, Sothy Yi
  • Amplification-based cloning method
    Patent number: 6607899
    Abstract: The invention provides a method for isolating a gene of interest from a cDNA library, which involves the use of an amplification step to amplify the gene of interest and an enrichment step to remove the template plasmids.
    Type: Grant
    Filed: April 9, 2002
    Date of Patent: August 19, 2003
    Inventors: Clarissa J. Chui, J. Christopher Grimaldi, Sean Milton, Minhong Yan, Sothy Yi
  • Novel tumor necrosis factor receptor homologs and nucleic acids encoding the same
    Publication number: 20030092044
    Abstract: The present invention is directed to novel polypeptides having homology to members of the tumor necrosis factor receptor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 12, 2002
    Publication date: May 15, 2003
    Applicant: Genentech, Inc.
    Inventors: Audrey Goddard, James Pan, Minhong Yan
  • Tumor necrosis factor receptor homologs and nucleic acids encoding the same
    Patent number: 6534061
    Abstract: The present invention is directed to novel polypeptides having homology to members of the tumor necrosis factor receptor family and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: April 12, 2000
    Date of Patent: March 18, 2003
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, James Pan, Minhong Yan
  • Cloning method
    Publication number: 20020168674
    Abstract: The invention provides a PCR-based method of cloning a gene of interest
    Type: Application
    Filed: April 9, 2002
    Publication date: November 14, 2002
    Applicant: Genentech, Inc.
    Inventors: Clarissa J. Chui, J. Christopher Grimaldi, Sean Milton, Minhong Yan, Sothy Yi