Patents by Inventor Miqin Zhang

Miqin Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Porous structures, and methods of use
    Patent number: 7736669
    Abstract: The present invention provides porous structures that each comprise chitosan, alginate and divalent metal cations, wherein: (a) the chitosan is ionically linked to the alginate; and (b) the structure is porous and has a compressive yield strength of at least 0.35 MPa. The present invention also provides methods for making the porous structures, and methods for using the porous structures as substrates to grow living cells.
    Type: Grant
    Filed: November 30, 2004
    Date of Patent: June 15, 2010
    Assignee: University of Washington
    Inventors: Miqin Zhang, Zhensheng Li
  • Nanoparticles having reactive ester groups covalently coupled thereto and related methods
    Patent number: 7666394
    Abstract: A particle having a core and a surface to which are covalently coupled a plurality of reactive ester groups. Methods for using the particle to prepare a particle having one or more of a plurality of a targeting agent, a diagnostic agent, or a therapeutic agent covalently coupled thereto.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: February 23, 2010
    Assignee: University of Washington
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Whitney Gunn
  • ARRAYS AND METHODS FOR GUIDED CELL PATTERNING
    Publication number: 20100041566
    Abstract: Guided cell patterning arrays for single cell patterning, methods for making the arrays, and methods for using the arrays.
    Type: Application
    Filed: July 2, 2009
    Publication date: February 18, 2010
    Applicant: WASHINGTON, UNIVERSITY OF
    Inventors: Miqin Zhang, Mandana Veiseh
  • ALGINATE-BASED NANOFIBERS AND RELATED SCAFFOLDS
    Publication number: 20090087469
    Abstract: Alginate nanofibers, scaffolds that include alginate nanofibers, implantable devices that include alginate nanofibers, and methods for making the alginate nanofibers by electrospinning.
    Type: Application
    Filed: September 26, 2008
    Publication date: April 2, 2009
    Applicant: Washington, University of
    Inventors: Miqin Zhang, Narayan Bhattarai
  • NANOPARTICLES HAVING REACTIVE ESTER GROUPS COVALENTLY COUPLED THERETO AND RELATED METHODS
    Publication number: 20090060846
    Abstract: A particle having a core and a surface to which are covalently coupled a plurality of reactive ester groups. Methods for using the particle to prepare a particle having one or more of a plurality of a targeting agent, a diagnostic agent, or a therapeutic agent covalently coupled thereto.
    Type: Application
    Filed: November 5, 2008
    Publication date: March 5, 2009
    Applicant: WASHINGTON, UNIVERSITY OF
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Whitney Gunn
  • Magnetic nanoparticle compositions and methods
    Patent number: 7462446
    Abstract: A nanoparticle having a core comprising a magnetic material and surface to which are covalently coupled a plurality of silane moieties, wherein each silane moiety comprises a polyalkylene oxide moiety. The nanoparticle can further include a targeting agent, a targeting agent and a diagnostic agent, or a targeting agent and a therapeutic agent. Methods for using the nanoparticle to detect and treat tissues of interest.
    Type: Grant
    Filed: March 20, 2006
    Date of Patent: December 9, 2008
    Assignee: University of Washington
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Whitney Gunn
  • Fluorescent chlorotoxin conjugate and method for intra-operative visualization of cancer
    Publication number: 20080279780
    Abstract: A chlorotoxin conjugate detectable by fluorescence imaging that allows for intra-operative visualization of cancerous tissues, compositions that include the chlorotoxin conjugate, and methods for using the chlorotoxin conjugate.
    Type: Application
    Filed: August 31, 2007
    Publication date: November 13, 2008
    Applicants: Washington, University of, Fred Hutchinson Cancer Research Center
    Inventors: Miqin Zhang, Richard G. Ellenbogen, Raymond W. Sze, Omid Veiseh, James M. Olson, Mandana Veiseh, Patrick Gabikian, S-Bahram Bahrami
  • METHOTREXATE-MODIFIED NANOPARTICLES AND RELATED METHODS
    Publication number: 20070269380
    Abstract: Methotrexate-modified nanoparticles that target tumors, compositions that include the nanoparticles, methods of imaging tissues using the nanoparticles, and methods for treating tissues using the nanoparticles.
    Type: Application
    Filed: October 10, 2006
    Publication date: November 22, 2007
    Applicants: Washington, University of, Industrial Technology Research Institute
    Inventors: Miqin Zhang, Shian-Jy Wang, Nathan Kohler, Yuh-Jiuan Lin, Conroy Sun
  • Chlorotoxin-labeled nanoparticle compositions and methods for targeting primary brain tumors
    Publication number: 20070154965
    Abstract: Chlorotoxin-labeled nanoparticles that target primary brain tumors, compositions that include the nanoparticles, methods of imaging tissues using the nanoparticles, and methods for treating tissues using the nanoparticles.
    Type: Application
    Filed: November 14, 2006
    Publication date: July 5, 2007
    Inventors: Miqin Zhang, James Olson, Raymond Sze, Richard Ellenbogen, Omid Veiseh, Conroy Sun, Jonathan Gunn
  • Biodegradable chitosan-peg compositions, and methods of use
    Publication number: 20060251613
    Abstract: The present invention provides compositions comprising an interpolymer of chitosan and polyethylene glycol, wherein the interpolymer is a liquid below 25° C. and a gel above 35° C. The present invention also provides methods for using the compositions to deliver drugs to a living body over time.
    Type: Application
    Filed: May 9, 2005
    Publication date: November 9, 2006
    Inventors: Miqin Zhang, Narayan Bhattarai, Frederick Matsen
  • Magnetic nanoparticle compositions and methods
    Publication number: 20060216239
    Abstract: A nanoparticle having a core comprising a magnetic material and surface to which are covalently coupled a plurality of silane moieties, wherein each silane moiety comprises a polyalkylene oxide moiety. The nanoparticle can further include a targeting agent, a targeting agent and a diagnostic agent, or a targeting agent and a therapeutic agent. Methods for using the nanoparticle to detect and treat tissues of interest.
    Type: Application
    Filed: March 20, 2006
    Publication date: September 28, 2006
    Applicant: Washington, University of
    Inventors: Miqin Zhang, Nathan Kohler, Jonathan Gunn
  • Porous structures, and methods of use
    Publication number: 20060115511
    Abstract: The present invention provides porous structures that each comprise chitosan, alginate and divalent metal cations, wherein: (a) the chitosan is ionically linked to the alginate; and (b) the structure is porous and has a compressive yield strength of at least 0.35 MPa. The present invention also provides methods for making the porous structures, and methods for using the porous structures as substrates to grow living cells.
    Type: Application
    Filed: November 30, 2004
    Publication date: June 1, 2006
    Applicant: University of Washington
    Inventors: Miqin Zhang, Zhensheng Li
  • Methods for making porous ceramic structures
    Publication number: 20050158535
    Abstract: In one aspect, the present invention provides methods for making porous ceramic structures. In another aspect, the present invention provides porous ceramic structures that have a compressive strength of greater than about 5 MPa. In another aspect, the present invention provides methods for growing bone.
    Type: Application
    Filed: May 14, 2004
    Publication date: July 21, 2005
    Inventors: Miqin Zhang, Hassna Ramay