Patents by Inventor Miroslav Klain

Miroslav Klain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6475186
    Abstract: A cardiopulmonary bypass system includes an aortic balloon cannula and a fluid flow cannula configured for connection to a cardiopulmonary bypass pump. The aortic balloon cannula includes an elongated tube device with first and second inflatable balloons mounted on the tube device and first and second lumen sized to communicate blood from the cardiopulmonary bypass pump to the patient's aorta. The cardiopulmonary bypass pump is configured to selectively deliver blood to the patient through the aortic balloon cannula and/or the fluid flow cannula at first, second and third temperatures.
    Type: Grant
    Filed: December 26, 2000
    Date of Patent: November 5, 2002
    Inventors: Peter Safar, S. William Stezoski, Miroslav Klain
  • Patent number: 6165162
    Abstract: What is disclosed is a portable and modular cardiopulmonary bypass apparatus and method. The apparatus includes (i) a first cannula assembly for withdrawing blood from a patient, (ii) a pump connected to the first cannula assembly for receiving the withdrawn blood and for moving the blood through the apparatus, and (iii) a first tubing connected to the pump to transport the patient's blood away from the pump. The apparatus also includes (iv) an oxygenator for receiving blood from the first tubing and for oxygenating the blood and (v) a second cannula assembly connected to the oxygenator for returning the oxygenated blood to the patient. The apparatus may be portable so that it can be used by medical personnel anywhere. In addition, the apparatus is adapted to included one or more modules for conditioning the blood, such as modules that include a heat exchanger, blood purifier, plasma and blood cell apheresis device and others. An aortic balloon catheter is also provided.
    Type: Grant
    Filed: September 14, 1998
    Date of Patent: December 26, 2000
    Assignee: University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Peter Safar, S. William Stezoski, Miroslav Klain
  • Patent number: 5906588
    Abstract: The selective and differential perfusion method includes withdrawing blood through a cannula introduced into a patient's blood vessel. The temperature of such blood is controlled and flowed through an arterial cannula introduced into a selected arterial vessel of the patient for a sufficient time and at a sufficient flow rate to change the temperature of at least a portion of the patient's body. An aortic balloon catheter is introduced into the aorta of the patient to establish fluid communication through the catheter lumen between an external location and an aortic location which is disposed in a preferential flow relationship with a selected branch artery of the aorta leading to a selected region of the patient's body. A balloon mounted on the exterior of said aortic catheter is positioned at a balloon location spaced longitudinally from the aortic location and inflated to resist blood flow while a fluid is communicated through the catheter lumen between the external location and the aortic location.
    Type: Grant
    Filed: August 11, 1997
    Date of Patent: May 25, 1999
    Assignee: Cardeon Corporation
    Inventors: Peter Safar, S. William Stezoski, Miroslav Klain
  • Patent number: 5879316
    Abstract: The portable and modular cardiopulmonary bypass apparatus has met the above mentioned needs. The apparatus consists of (i) a first cannula assembly means for withdrawing blood from a patient, (ii) a pump means connected to the first cannula assembly means for receiving the withdrawn blood and for moving the blood through the apparatus, and (iii) a first tubing means connected to the pump means to transport the patient's blood away from the pump means. The apparatus further comprises (iv) oxygenator means for receiving blood from the first tubing means and for oxygenating the blood and (v) second cannula assembly means connected to the oxygenator means for returning the oxygenated blood to the patient. The apparatus is portable so that it can be used by medical personnel anywhere. In addition, the apparatus is adapted to include one or more modules for conditioning the blood, such as modules that include a heat exchanger, blood purifier, plasma and blood cell apheresis device and others.
    Type: Grant
    Filed: April 10, 1997
    Date of Patent: March 9, 1999
    Assignee: University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Peter Safar, S. William Stezoski, Miroslav Klain
  • Patent number: 5820593
    Abstract: An aortic balloon catheter including an elongated tube device formed with a first lumen sized to communicate blood between an aortic lumen of an adult human patient and a location external to the aortic lumen. Mounted on the tube device is an inflatable balloon which is sized to resist or block blood flow through the aortic lumen. The associated method of using the aortic balloon catheter includes introducing the catheter into the aortic lumen of an adult human, positioning the first lumen and the balloon, inflating the balloon and withdrawing and perfusing fluids through the first lumen.
    Type: Grant
    Filed: April 25, 1996
    Date of Patent: October 13, 1998
    Assignee: University of Pittsburg of the Commonwealth System of Higher Education
    Inventors: Peter Safar, S. William Stezoski, Miroslav Klain
  • Patent number: 5383854
    Abstract: The portable and modular cardiopulmonary bypass apparatus has met the above mentioned needs. The apparatus consists of (i) a first cannula assembly means for withdrawing blood from a patient, (ii) a pump means connected to the first cannula assembly means for receiving the withdrawn blood and for moving the blood through the apparatus, and (iii) a first tubing means connected to the pump means to transport the patient's blood away from the pump means. The apparatus further comprises (iv) oxygenator means for receiving blood from the first tubing means and for oxygenating the blood and (v) second cannula assembly means connected to the oxygenator means for returning the oxygenated blood to the patient. The apparatus is portable so that it can be used by medical personnel anywhere. In addition, the apparatus is adapted to include one or more modules for conditioning the blood, such as modules that include a heat exchanger, blood purifier, plasma and blood cell apheresis device and others.
    Type: Grant
    Filed: August 19, 1992
    Date of Patent: January 24, 1995
    Assignee: University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Peter Safar, S. William Stezoski, Miroslav Klain
  • Patent number: 5308320
    Abstract: The portable and modular cardiopulmonary bypass apparatus has met the above mentioned needs. The apparatus consists of (i) a first cannula assembly means for withdrawing blood from a patient, (ii) a pump means connected to the first cannula assembly means for receiving the withdrawn blood and for moving the blood through the apparatus, and (iii) a first tubing means connected to the pump means to transport the patient's blood away from the pump means. The apparatus further comprises (iv) oxygenator means for receiving blood from the first tubing means and for oxygenating the blood and (v) second cannula assembly means connected to the oxygenator means for returning the oxygenated blood to the patient. The apparatus is portable so that it can be used by medical personnel anywhere. In addition, the apparatus is adapted to include one or more modules for conditioning the blood, such as modules that include a heat exchanger, blood purifier, plasma and blood cell apheresis device and others.
    Type: Grant
    Filed: December 28, 1990
    Date of Patent: May 3, 1994
    Assignee: University of Pittsburgh of the Commonwealth System of Higher Education
    Inventors: Peter Safar, S. William Stezoski, Miroslav Klain