Patents by Inventor Miroslava Zertova

Miroslava Zertova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Analogues of 8-D-homoarginine vasopressin
    Patent number: 5486596
    Abstract: Analogues of 8-D-homoarginine vasopressin were prepared with the general formula ##STR1## where X is L-O-methyltyrosine, L-p-ethylphenylalanine, D-p-ethylphenylalanine, L-p-methylphenylalanine or D-methylphenylalanine and R is cysteine or .beta.-mercaptopropionic acid. These vasopressin analogues exhibited an increased affinity to uterus receptors for oxytocin, where they acted as ocytocin antagonists. Moreover, the analogues of deamino vasopressin have a significantly reduced antidiuretic activity in comparison with [8-D-arginine]vasopressin.
    Type: Grant
    Filed: August 25, 1993
    Date of Patent: January 23, 1996
    Assignee: Ceskoslovenska akademie ved
    Inventors: Zdenko Prochazka, Ivo Blaha, Miroslava Zertova, Jirina Slaninova, Jiri Velek, Jana Skopkova, Michal Lebl, Tomislav Barth, Lenka Maletinska, Hans Vilhardt