Patents by Inventor Miroslaw Bobrowski

Miroslaw Bobrowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibiotic derivatives of polyene macrolide group and method of obtaining the same
    Patent number: 4093796
    Abstract: A new class of polyene macrolide antibiotics which exhibit valuable therapeutic properties are obtained by reaction of said antibiotics containing at least one amino group with mono- or oligosaccharides, and/or their derivatives in a suitable solvent.A series of such have been obtained and examined. They all exhibit a high biological activity and form salts which are soluble in water.Said sugar derivatives of antibiotics can be used as antifungal agents, also as substances to reduce the overgrowth of the prostrate gland and cholesterol level in the blood.
    Type: Grant
    Filed: August 10, 1972
    Date of Patent: June 6, 1978
    Assignee: Politechnika Gdanska
    Inventors: Leonard Falkowski, Miroslaw Bobrowski, Helena Buluk, Elzbieta Bylec, Barbara Cybulska, Jerzy Golik, Pawel Kolodziejczyk, Jan Pawlak, Andrzej Rudowski, Jan Zielinski, Tadeusz Ziminski, Edward Borowski
  • Desalanyltetaine derivatives and the method for their preparation
    Patent number: 4092335
    Abstract: The subject of this invention are the desalanyltetaine derivatives of the formula 1, wherein R.sup.1 is a hydroxyl group or an arrangement of the formula 2, wherein R.sup.3 is a hydrogen atom or an alkyl, aryl, aralkyl group and X is an acyl or alkyl group, R.sup.2 is a hydrogen atom or an acyl group, and Z is an oxygen atom, hydroxylamine or hydrazine radical or their alkyl, aryl or aralkyl derivatives.The method of the preparation of the derivatives according to the invention consists in treating the desalanyltetaine derivatives of the formula 1, where R.sup.1 and R.sup.2 have the above mentioned significance, and Z is an oxygen atom with hydroxylamine, hydrazine or their derivatives. A modification of the method consists in treating the desalanyltetaine of the formula 1, where R.sup.2 and Z have the above mentioned significance, and R.sup.1 is a hydroxyl group with the chloroethers.Another modification of the method consists in the fact that the desalanyltetaine derivatives of the formula 1 where R.sup.
    Type: Grant
    Filed: November 5, 1976
    Date of Patent: May 30, 1978
    Assignee: Politechnika Gdanska
    Inventors: Wojciech Gruszecki, Edward Bordwski, Jerzy Gumieniak, Malgorzata Gumieniak, Maciej Smulkowski, Hanna Wojciechowska, Miroslaw Bobrowski