Patents by Inventor Mohammed Nur-E-Alam

Mohammed Nur-E-Alam has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090298804
    Abstract: The present invention relates to 15-desmethoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.
    Type: Application
    Filed: March 30, 2007
    Publication date: December 3, 2009
    Inventors: Sabine Gaisser, Christine Martin, Ming Zhang, Barrie Wilkinson, Nigel Coates, Mohammed Nur-E-Alam, Nikolaos Galtatzis
  • Publication number: 20090209507
    Abstract: The present invention relates to 15-O-desmethylmacbecin analogues according to the formula (IA) or (IB) herein, or a pharmaceutically acceptable salt thereof: wherein: R1 and R2 either both represent H or together they represent a bond (i.e. C4 to C5 is a double bond); and R3 represents H or CONH2 that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.
    Type: Application
    Filed: March 30, 2007
    Publication date: August 20, 2009
    Inventors: Sabine Gaisser, Christine Martin, Ming Zhang, Barrie Wilkinson, Nigel Coates, Mohammed Nur-E-Alam, William Vousden
  • Publication number: 20090209494
    Abstract: The present invention relates to 21-deoxymacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and or prophylaxis of cancer or B-cell malignancies.
    Type: Application
    Filed: December 22, 2006
    Publication date: August 20, 2009
    Inventors: Christine Janet Martin, Barrie Wilkinson, Sabine Gaisser, Ming-Oiang Zhang, Rose Mary Sheridan, Lesley Sarah Sheehan, Rachel Edith Lill, Mohammed Nur-E-Alam, William Alexander Vousden
  • Publication number: 20090117127
    Abstract: The present invention relates to 11-O-desmethylmacbecin analogues that are useful, e.g. in the treatment of cancer, B-cell malignancies, malaria, fungal infection, diseases of the central nervous system and neurodegenerative diseases, diseases dependent on angiogenesis, autoimmune diseases and/or as a prophylactic pretreatment for cancer. The present invention also provides methods for the production of these compounds and their use in medicine, in particular in the treatment and/or prophylaxis of cancer or B-cell malignancies.
    Type: Application
    Filed: March 30, 2007
    Publication date: May 7, 2009
    Inventors: Sabine Gaisser, Christine Martin, Ming Zhang, Barrie Wilkinson, Lesley Sheehan, Nigel Coates, Mohammed Nur-E-Alam, William Vousden, Nikolaos Gaitatzis