Abstract: A tooth bracket extraction device which comprises a motor housed within a motor housing, and a motor shaft extending from the motor. A gear cover is fastened to the motor housing, and a first shaft is coupled to the motor shaft, where the first shaft receives the drive from the motor via the motor shaft. A first gear is attached to the first shaft, and a second shaft comprises a second gear, where the second shaft is in communication with the first shaft via engagement of the second gear to the first gear. A torque generated from the motor is transferred to the second shaft, and the second shaft comprises a head receiver member which is configured to receive and mount a plurality of heads. Each head is configured to transfer the torque to a bracket section attached to teeth, thereby removing the bracket section from the teeth.

Abstract: A tooth bracket extraction device which comprises a motor housed within a motor housing, and a motor shaft extending from the motor. A gear cover is fastened to the motor housing, and a first shaft is coupled to the motor shaft, where the first shaft receives the drive from the motor via the motor shaft. A first gear is attached to the first shaft, and a second shaft comprises a second gear, where the second shaft is in communication with the first shaft via engagement of the second gear to the first gear. A torque generated from the motor is transferred to the second shaft, and the second shaft comprises a head receiver member which is configured to receive and mount a plurality of heads. Each head is configured to transfer the torque to a bracket section attached to teeth, thereby removing the bracket section from the teeth.

Abstract: The invention provides methods to process multiple microarrays by providing a microarray plate and processing plates. In an embodiment of the invention, methods for assembling microarray plates by using wafers are described for high throughput microarray processing.

Abstract: A system and method for processing biological sensors. The system includes a support component configured to support a fluidic component. The fluidic component includes at least a first container and a second container. The first container is capable of holding a first volume of a first fluid, and the second container is capable of holding a second volume of a second fluid. Additionally, the system includes a hybridization component configured to perform a hybridization process on a first sensor and a second sensor. Moreover, the system includes a transport component configured to move the first sensor, directly or indirectly, from the hybridization component into the first container and in contact with the first volume of the first fluid.

Abstract: The invention provides methods to process multiple microarrays by providing a microarray plate and processing plates. In an embodiment of the invention, methods for assembling microarray plates by using wafers are described for high throughput microarray processing.

Abstract: The invention provides sensor plates, particularly plates having a plurality of sensors, and related methods for assembling such plates. The sensors can be arrays of probes, such as microarrays, including high density oligonucleotide microarrays. The methods include the steps of selecting a substrate having a plurality of sensors, aligning the substrate to a support plate, and attaching the substrate to the support plate. Moduled sensor plates, and methods of assembling such plates, are also provided. The moduled sensor plates can include a plurality of sensor plates, such as sensor or microarray strip plates, with each strip plate having an attachment feature that is used to attach the strip plate to a frame. The sensor plates and moduled sensor plates can be inserted into processing plates, including hybridization plates, washing plates, staining plates, and detection plates.

Abstract: The invention provides methods and components for assembly of arrays of sensors from modular units containing component sensors of the array. The methods are particularly useful for forming arrays of microarrays. The sensor modules can readily be assembled in different combinations thereby allowing many different modular sensor arrays to be assembled from the same building blocks. Such modular sensor arrays offer advantages of economies of scale for a manufacturer of the modular units and flexibility for an end user in allowing the user to customize the array of sensor according to the user's own needs from a relatively small number of sensor modules provided by the manufacturer.

Abstract: The invention provides methods to process multiple microarrays by providing a microarray plate and processing plates. In an embodiment of the invention, methods for assembling microarray plates by using wafers are described for high throughput microarray processing.

Abstract: Novel processes are disclosed for the large scale preparation of arrays of polymer sequences wherein each array includes a plurality of different, positionally distinct polymer sequences having known monomer sequences. In one embodiment, two substrates are processed simultaneously in a reaction chamber, wherein the substrates are facing each other and in contact with a monomer solution. In a further embodiment, multiple rotating flow cells are used in combination with a photolysis equipment to synthesize wafers.

Abstract: A device, method and system for ensuring proper orientation and installation of trays for processing biological sensors in an automated and flexible system are provided. The system comprises an instrument handling robot that transfers a plurality of arrays mounted on pegs on a strip to liquid reaction stations. In particular, the method comprises a first orientation marking on a tray and a second orientation marking on a deck, indicating the proper station in which the tray is placed for a specific process.

Abstract: A fluidic system and method for processing biological sensors. The fluidic system includes a fluidic component including at least a first container and a second container. The first container is capable of holding a first volume of a first fluid, and the second container is capable of holding a second volume of a second fluid. Additionally, the fluidic system includes a support component configured to support at least the first container and the second container. The first container and the second container are substantially stationary with respect to the support component. Moreover, the fluidic system includes a transport component configured to move a first sensor, with respect to the support component, into the first container and in contact with the first volume of the first fluid, and move a second sensor, with respect to the support component, into the second container and in contact with the second volume of the second fluid.

Abstract: A system and method for processing biological sensors. The system includes a support component configured to support a fluidic component. The fluidic component includes at least a first container and a second container. The first container is capable of holding a first volume of a first fluid, and the second container is capable of holding a second volume of a second fluid. Additionally, the system includes a hybridization component configured to perform a hybridization process on a first sensor and a second sensor. Moreover, the system includes a transport component configured to move the first sensor, directly or indirectly, from the hybridization component into the first container and in contact with the first volume of the first fluid.

Abstract: A fluidic system and method for processing biological sensors. The fluidic system includes a fluidic component including at least a first container and a second container. The first container is capable of holding a first volume of a first fluid, and the second container is capable of holding a second volume of a second fluid. Additionally, the fluidic system includes a support component configured to support at least the first container and the second container. The first container and the second container are substantially stationary with respect to the support component. Moreover, the fluidic system includes a transport component configured to move a first sensor, with respect to the support component, into the first container and in contact with the first volume of the first fluid, and move a second sensor, with respect to the support component, into the second container and in contact with the second volume of the second fluid.

Abstract: A system and method for processing biological sensors. The system includes a support component configured to support a fluidic component. The fluidic component includes at least a first container and a second container. The first container is capable of holding a first volume of a first fluid, and the second container is capable of holding a second volume of a second fluid. Additionally, the system includes a hybridization component configured to perform a hybridization process on a first sensor and a second sensor. Moreover, the system includes a transport component configured to move the first sensor, directly or indirectly, from the hybridization component into the first container and in contact with the first volume of the first fluid.

Abstract: In one embodiment of the invention, methods are provided for collecting the content of microtiter plate well An automated pipett is programmed to aspirate along the wall of a microtiter well at defined intervals to collect liquid that may be on the walls of the well

Abstract: In one aspect of the invention, a fully automated parallel microarray processing system is provided. The system is capable of high throughput processing of microarrays, from sample preparation to hybridization, without human intervention.

Abstract: In one embodiment of the invention, methods are provided for collecting the content of microtiter plate well. An automated pipett is programmed to aspirate along the wall of a microtiter well at defined intervals to collect liquid that may be on the walls of the well.