Patents by Inventor Monroe J. Stutts, III

Monroe J. Stutts, III has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dinucleotides useful for the treatment of cystic fibrosis and for hydrating mucus secretions
    Patent number: 5635160
    Abstract: A compound of Formula (I), or a pharmaceutically acceptable salt thereof, is disclosed: ##STR1## wherein: n is from 1 to 6;X is --OH or --SH;A and B are each independently selected from the group consisting of: ##STR2## wherein R is H or Br. The compounds are useful in the treatment of airway diseases such as cystic fibrosis. Pharmaceutical formulations comprising a compound of Formula (I), and methods of hydrating mucous secretions in the lungs of a subject in need of such treatment, comprising administering to the lungs of the subject a compound of Formula I as given above, are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: June 3, 1997
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Monroe J. Stutts, III, Richard C. Boucher, Jr., Eduardo R. Lazarowski, Cara A. Geary