Patents by Inventor Motoko Kimura

Motoko Kimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10513561
    Abstract: The present invention provides an anti-Myl9 antibody or a Myl9 binding fragment thereof that binds to Myl9 and may inhibit the interaction between Myl9 and CD69 in humans, as well as a pharmaceutical composition comprising the same. A mouse anti-human/mouse Myl9 monoclonal antibody having binding affinity against Myl9 was obtained, and the sequence for the complementarity determining region (CDR) of said mouse anti-human/mouse Myl9 monoclonal antibody was identified. Accordingly, a humanized antibody comprising the CDR sequence of said mouse anti-human/mouse Myl9 monoclonal antibody in the variable region of heavy and light chains was produced.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: December 24, 2019
    Assignees: National University Corporation Chiba University, Eisai R&D Management Co., Ltd.
    Inventors: Toshinori Nakayama, Motoko Kimura, Koji Hayashizaki, Toshifumi Hirayama, Jungo Kakuta, Yoshimasa Sakamoto, Ryu Gejima, Daisuke Tokita, Kenzo Muramoto, Toshio Imai
  • Publication number: 20190002588
    Abstract: The present invention provides an anti-Myl9 antibody or a Myl9 binding fragment thereof that binds to Myl9 and may inhibit the interaction between Myl9 and CD69 in humans, as well as a pharmaceutical composition comprising the same. A mouse anti-human/mouse Myl9 monoclonal antibody having binding affinity against Myl9 was obtained, and the sequence for the complementarity determining region (CDR) of said mouse anti-human/mouse Myl9 monoclonal antibody was identified. Accordingly, a humanized antibody comprising the CDR sequence of said mouse anti-human/mouse Myl9 monoclonal antibody in the variable region of heavy and light chains was produced.
    Type: Application
    Filed: January 11, 2017
    Publication date: January 3, 2019
    Inventors: Toshinori Nakayama, Motoko Kimura, Koji Hayashizaki, Toshifumi Hirayama, Jungo Kakuta, Yoshimasa Sakamoto, Ryu Gejima, Daisuke Tokita, Kenzo Muramoto, Toshio Imai
  • Patent number: 7401393
    Abstract: The present invention provides a method for removing solder adhering to an LSI. In this method, a plate-shaped first member for causing molten solder to adhere thereto is mounted on top of a heater. An LSI is placed on top of the first member with the surface on which solder is attached facing downward. A second member for adding a load to the LSI is placed on top of the LSI. The heater is heated up to heat the first member and the LSI, and to melt the solder. The molten solder is transferred to the first member. A suction mechanism is positioned at a location a predetermined distance away from the top surface of the second member. The second member and the LSI are attracted by the suction mechanism, and the LSI is pulled away from the first member. The solder is thereby removed from the LSI.
    Type: Grant
    Filed: May 17, 2004
    Date of Patent: July 22, 2008
    Assignee: Hitachi, Ltd.
    Inventors: Motoko Kimura, Takeshi Miitsu, Takeshi Takahashi, Kaoru Katayama, Shiro Yamashita
  • Publication number: 20040206805
    Abstract: The present invention provides a method for removing solder adhering to an LSI. In this method, a plate-shaped first member for causing molten solder to adhere thereto is mounted on top of a heater. An LSI is placed on top of the first member with the surface on which solder is attached facing downward. A second member for adding a load to the LSI is placed on top of the LSI. The heater is heated up to heat the first member and the LSI, and to melt the solder. The molten solder is transferred to the first member. A suction mechanism is positioned at a location a predetermined distance away from the top surface of the second member. The second member and the LSI are attracted by the suction mechanism, and the LSI is pulled away from the first member. The solder is thereby removed from the LSI.
    Type: Application
    Filed: May 17, 2004
    Publication date: October 21, 2004
    Applicant: Hitachi, Ltd.
    Inventors: Motoko Kimura, Takeshi Miitsu, Takeshi Takahashi, Kaoru Katayama, Shiro Yamashita
  • Patent number: 6739045
    Abstract: The present invention provides a method for removing solder adhering to an LSI. In this method, a plate-shaped first member for causing molten solder to adhere thereto is mounted on top of a heater. An LSI is placed on top of the first member with the surface on which solder is attached facing downward. A second member for adding a load to the LSI is placed on top of the LSI. The heater is heated up to heat the first member and the LSI, and to melt the solder. The molten solder is transferred to the first member. A suction mechanism is positioned at a location a predetermined distance away from the top surface of the second member. The second member and the LSI are attracted by the suction mechanism, and the LSI is pulled away from the first member. The solder is thereby removed from the LSI.
    Type: Grant
    Filed: July 9, 2002
    Date of Patent: May 25, 2004
    Assignee: Hitachi, Ltd.
    Inventors: Motoko Kimura, Takeshi Miitsu, Takeshi Takahashi, Kaoru Katayama, Shiro Yamashita
  • Publication number: 20030034380
    Abstract: The present invention provides a method for removing solder adhering to an LSI. In this method, a plate-shaped first member for causing molten solder to adhere thereto is mounted on top of a heater. An LSI is placed on top of the first member with the surface on which solder is attached facing downward. A second member for adding a load to the LSI is placed on top of the LSI. The heater is heated up to heat the first member and the LSI, and to melt the solder. The molten solder is transferred to the first member. A suction mechanism is positioned at a location a predetermined distance away from the top surface of the second member. The second member and the LSI are attracted by the suction mechanism, and the LSI is pulled away from the first member. The solder is thereby removed from the LSI.
    Type: Application
    Filed: July 9, 2002
    Publication date: February 20, 2003
    Applicant: Hitachi, Ltd.
    Inventors: Motoko Kimura, Takeshi Miitsu, Takeshi Takahashi, Kaoru Katayama, Shiro Yamashita
  • Patent number: 5556848
    Abstract: An ophthalmic suspension comprising difluprednate as an active ingredient. The ophthalmic suspension of the present invention shows superior antiinflammatory action and antiallergic action by local administration. Accordingly, the suspension of the present invention is useful for the treatment and prevention of disorders of the eye, such as allergic conjunctivitis, vernal conjunctivitis, blepharitis marginalis, catarrhal conjunctivitis and uveitis.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: September 17, 1996
    Assignees: Senju Pharmaceutical Co., Ltd., Mitsubishi Chemical Corporation
    Inventors: Motoko Kimura, Yasushi Morita, Takahiro Ogawa, Tadashi Terai
  • Patent number: 5419898
    Abstract: There is disclosed an antiallergic composition for ophthalmic or nasal use, comprising cetirizine or a salt thereof as an active ingredient. The antiallergic composition may further contain a cyclodextrin compound, as well as a surfactant and/or a water soluble polymer.
    Type: Grant
    Filed: December 20, 1993
    Date of Patent: May 30, 1995
    Assignee: Senju Pharmacuetical Co., Ltd.
    Inventors: Yoshifumi Ikejiri, Takahiro Ogawa, Fuminori Tokumochi, Shogo Sameshima, Motoko Kimura