Abstract: There is proposed a method for the sterilization of products containing bacteriophages in a manner that will allow the bacteriophages to retain their activity and infectivity. Products containing bacteriophages are exposed to supercritical CO2 under conditions causing little or no damage to structural integrity of the bacteriophages or to the structural properties of biodegradable scaffolds containing the bacteriophages.

Abstract: A composition for delivering at least one Non-Steroidal Anti-Inflammatory Drug (NSAID) to a subject, the composition including biodegradable nanospheres, wherein the biodegradable nanospheres include the NSAID dispersed in a biodegradable polymer.

Abstract: A method of eliminating, reducing or preventing bacterial contamination of a surface, the method comprising dispersing a bacteriophage containing composition in air in proximity to the surface. In some embodiments, the bacteriophage containing composition is a powder dispersed by pressurizing a load chamber containing the powder so that the powder is expelled through an outlet. Also, devices for performing the method and a powder used in the method.

Abstract: Cannabidiol (CBD) is the major nonpsychotropic constituent of cannabis, having numerous applications in the management of clinical conditions, including the treatment of chronic pain. The delivery of CBD and other cannabinoids is hindered by poor bioavailability, low aqueous solubility, and instability in the solution form, hepatic first pass effect, enzymatic degradation in the gut, and mucociliary clearance. We propose the encapsulation of cananbinoids in biodegradable polyester amide urea polymer, and in similar polymers, for the optimized prolonged topical delivery and permeability of CBD for pain, inflammation and other conditions.

Abstract: A method of treating, reducing or preventing bacterial infection in a wound, the method comprising: applying a film on the wound, the film including a biodegradable polymer with bacteriophages dispersed therein, wherein the polymer is a poly (ester amide urea).

Abstract: There is proposed a method for the sterilization of products containing bacteriophages in a manner that will allow the bacteriophages to retain their activity and infectivity. Products containing bacteriophages are exposed to supercritical CO2 under conditions causing little or no damage to structural integrity of the bacteriophages or to the structural properties of biodegradable scaffolds containing the bacteriophages.

Abstract: A method of promoting wound healing in a patient, the method comprising applying on a wound a biodegradable amino-acid based polymer.

Abstract: A method of treating, reducing or preventing bacterial infection in a wound, the method comprising: applying a film on the wound, the film including a biodegradable polymer with bacteriophages dispersed therein, wherein the polymer is a poly (ester amide urea).

Abstract: A method of treating, reducing or preventing bacterial infection in a wound, the method comprising: applying a film on the wound, the film including a biodegradable polymer with bacteriophages dispersed therein, wherein the polymer is a poly (ester amide urea).

Abstract: An encapsulated bacteriophage formulation and a method for encapsulating bacteriophages and bacteriophage-related products in polymeric microcapsules is provided. Some embodiments of the method of producing the encapsulated bacteriophages involves a water-in-oil-in-water double emulsion.

Abstract: An encapsulated bacteriophage formulation and a method for encapsulating bacteriophages and bacteriophage-related products in polymeric microcapsules is provided. Some embodiments of the method of producing the encapsulated bacteriophages involves a water-in-oil-in-water double emulsion.

Abstract: A medical device, the medical device including a substrate defining a surface; a plasma polymer layer bound to and coating the surface; and a bactericide layer bound to the plasma polymer layer, the plasma polymer layer being between the substrate and the bactericide layer. Also, a method for coating a surface of a substrate of a medical device with a bactericide layer, the method including: exposing the surface to a plasma to form a plasma polymer layer bound to the surface; and binding a bactericide layer to the plasma polymer layer.

Abstract: A medical device, the medical device including a substrate defining a surface; a plasma polymer layer bound to and coating the surface; and a bactericide layer bound to the plasma polymer layer, the plasma polymer layer being between the substrate and the bactericide layer. Also, a method for coating a surface of a substrate of a medical device with a bactericide layer, the method including: exposing the surface to a plasma to form a plasma polymer layer bound to the surface; and binding a bactericide layer to the plasma polymer layer.

Abstract: An encapsulated bacteriophage formulation and a method for encapsulating bacteriophages and bacteriophage-related products in polymeric microcapsules is provided. Some embodiments of the method of producing the encapsulated bacteriophages involves a water-in-oil-in-water double emulsion.

Abstract: An encapsulated bacteriophage formulation and a method for encapsulating bacteriophages and bacteriophage-related products in polymeric microcapsules is provided. Some embodiments of the method of producing the encapsulated bacteriophages involves a water-in-oil-in-water double emulsion.

Abstract: A method of treating, reducing or preventing bacterial infection in a wound, the method comprising: applying a film on the wound, the film including a biodegradable polymer with bacteriophages dispersed therein, wherein the polymer is a poly (ester amide urea).

Abstract: Amino acid based polymers and polymer blends. Compositions comprising at least one amino acid based polymer or polymer blend, at least one bioactive agent, and optionally at least one filler. Additionally, compositions comprising at least one bacteriophage and at least one salt or buffer, which, for example, are in the form of a dry powder, and methods of preparing thereof are disclosed.

Abstract: An encapsulated bacteriophage formulation and a method for encapsulating bacteriophages and bacteriophage-related products in polymeric microcapsules is provided. Some embodiments of the method of producing the encapsulated bacteriophages involves a water-in-oil-in-water double emulsion.

Abstract: Amino acid based polymers and polymer blends. Compositions comprising at least one amino acid based polymer or polymer blend, at least one bioactive agent, and optionally at least one filler. Additionally, compositions comprising at least one bacteriophage and at least one salt or buffer, which, for example, are in the form of a dry powder, and methods of preparing thereof are disclosed.