Abstract: A discharge device which discharges a sheet includes: a driving shaft which is driven to rotate by a driving source; a plurality of driving rotating members which is provided on the driving shaft; a rotating member which is provided on the driving shaft, has a larger outside diameter than an outside diameter of the driving rotating member, is formed by joining at least two divided components, and includes stepped portions that protrude, to a larger extent, in a radial direction in boundary portions of the at least two components on upstream sides of a rotation direction of the rotating member than on downstream sides thereof; and follower rotating members which are pressed against the driving rotating members.

Abstract: Disclosed is a compound which is useful as an endothelial lipase inhibitor.

Abstract: A compound represented by formula: its pharmaceutically acceptable salt, or a solvate thereof. Ring B is substituted or unsubstituted nitrogen-containing hetero ring, R2 and R3 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl or substituted or unsubstituted alkyloxy, R2 and R3 taken together may form oxo, R4 is a group represented by the formula: —(CR6R7)n—R8, R6 and R7 are each independently hydrogen, halogen, hydroxy, carboxy, substituted or unsubstituted alkyl or substituted or unsubstituted alkyloxy, R6 and R7 taken together with the adjacent carbon atom to which they are attached may form a substituted or unsubstituted ring, and n is an integer of 0 to 3.

Abstract: A pharmaceutical composition including a compound of formula (I): its pharmaceutically acceptable salt, or a solvate thereof. Ring A is nitrogen-containing hetero ring, Ring A may be substituted with a substituent other than a group represented by formula: —C(R1R2)—C(?O)—NR3R4 and a group represented by formula: —R5, a broken line represents presence or absence of a bond, Z is —NR6—, ?N—, —O—, or —S—, R6 is halogen or substituted or unsubstituted alkyl, R1 and R2 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy or substituted or unsubstituted alkyl, R3 is hydrogen or substituted or unsubstituted alkyl, R4 is hydrogen or substituted or unsubstituted alkyl, R3 and R4 taken together with the adjacent nitrogen atom to which they are attached may form a substituted or unsubstituted ring, R5 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, or substituted or unsubstituted alkynyl.

Abstract: The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions.

Abstract: A compound represented by the formula: or its pharmaceutically acceptable salt. Ring A is aromatic carbocycle or aromatic heterocycle, Z is —O— or —S—, R1 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like, R2 and R3 are each independently hydrogen, halogen, hydroxy or the like, R4 is a group represented by the formula: —(CR6R7)n—R8, R6 and R7 are each independently hydrogen, halogen, hydroxy or the like, n is an integer of 0 to 3, R8 is carboxy, cyano, substituted or unsubstituted alkyl or the like, Rx is halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl or the like, and m is an integer of 0 to 3.

Abstract: A running form diagnosis system capable of automatically scoring a running form of a runner is provided. The running form diagnosis system obtains body motion information as to a test subject running on a treadmill, and calculate a running form score of the test subject by applying obtained characteristics to a given operation expression. The operation expression is generated based on correlation between characteristics of a plurality of test runners and comprehensive evaluation given by an expert with respect to the plurality of test runners.

Abstract: Provided are a substrate on which carbon nanotubes each having one end connected to the substrate can be formed at a high synthetic rate and from which the carbon nanotubes are less likely to be peeled off. The substrate is a substrate for forming the carbon nanotubes and includes a buffer layer 13 formed on at least one of surfaces of a substrate main body 14 and containing aluminum atoms and fluorine atoms. The carbon nanotube complex includes the substrate and a plurality of carbon nanotubes 11 each having one end connected to a surface of the buffer layer 13.

Abstract: Disclosed is a compound which is useful as an endothelial lipase inhibitor.

Abstract: A holder is disposed in the case. The holder is mounted with an actuator that moves in the predetermined direction and a wiring board having a detector. A positioning mechanism between relevant components for detecting the positions of components is provided such as a wiring board and a holder, the position of magnet in particular. In this way, the magnet and the detector opposing to each other are positioned. As a result, when a vehicle switch is assembled, the variation in position of the magnet and detector is reduced.

Abstract: Regarding a switch used for various controls of a motor vehicle in particular and a switch device using the switch, it becomes possible to simplify the configuration and to perform reliable detection of trouble. A first detector is disposed on a surface opposing to a magnet fitted to an actuator, and a second detector is disposed thereunder. A controller detects magnetism of the magnet by using the first detector and the second detector. In case one of the detectors is out of order, it can also be detected from ON/OFF signal from the first detector and the second detector.

Abstract: Provided are a substrate on which carbon nanotubes each having one end connected to the substrate can be formed at a high synthetic rate and from which the carbon nanotubes are less likely to be peeled off. The substrate is a substrate for forming the carbon nanotubes and includes a buffer layer 13 formed on at least one of surfaces of a substrate main body 14 and containing aluminum atoms and fluorine atoms. The carbon nanotube complex includes the substrate and a plurality of carbon nanotubes 11 each having one end connected to a surface of the buffer layer 13.

Abstract: Disclosed is a compound which is useful as an endothelial lipase inhibitor.

Abstract: Unlike related art in which a variety of recycling aluminum materials are directly inputted into a pre-rolling melting furnace, the present invention provides the step of melting used planographic printing plates roughened by hydrochloric acid-based electrolysis in another melting furnace into a recycled metal ingot having a predetermined shape and weight and the step of using the results obtained by analyzing the recycled metal ingot to determine the mix proportions of the recycled metal ingot, the fresh metal ingot, and the trace metal master alloy to be inputted into the pre-rolling melting furnace. As a result, the amount of CO2 produced at the time of manufacture can be greatly reduced, and an aluminum plate having an aluminum purity of 99.0% or higher, which is required in a hydrochloric acid-based electrolytic roughening, can be manufactured.

Abstract: A compound represented by the general formula (I-A): wherein R1 is hydroxy and the like; R2 is optionally substituted lower alkyl and the like; R3 is hydrogen atom and the like; R4 is optionally substituted arylene and the like; R5 is a group represented by the formula: R6 is optionally substituted aryl and the like, its optically active substance, their pharmaceutically acceptable salt, or a solvate thereof; and a metalloproteinase inhibitor containing them.

Abstract: The present invention provides a more efficient industrial method for producing a pyrazol-3-yl-benzamide derivative expressed by a formula useful as medicine: wherein R2, R3 and R4 each independently represent a lower alkyl group.

Abstract: Processes for the preparation of certain [3.1.0]hexane derivatives which are useful as mGluR agonists, and intermediates prepared during such processes.

Abstract: The present invention relates to substituted pyrazoles, compositions containing such compounds and methods of treatment. The compounds are glucagon receptor antagonists and thus are useful for treating, preventing or delaying the onset of type 2 diabetes mellitus.

Abstract: The present invention describes an efficient and economical process for the preparation of a 2,3-disubstituted 2-phenyl-1h-phenantrho[9,10-d]imidazole derivative that is useful for the large scale production of material for preclinical and clinical use. The process of the present invention represents a convergent approach to generate the 2,3-disubstituted 2-phenyl-1h-phenantrho[9,10-d]imidazole derivative in high overall yield. The compound made by the process of the invention is an inhibitor of the microsomal prostaglandin E synthase-1 (mPGES-1) enzyme and is therefore useful to treat pain and/or inflammation from a variety of diseases or conditions, such as osteoarthritis, rheumatoid arthritis and acute or chronic pain.

Abstract: A holder is disposed in the case. The holder is mounted with an actuator that moves in the predetermined direction and a wiring board having a detector. A positioning mechanism between relevant components for detecting the positions of components is provided such as a wiring board and a holder, the position of magnet in particular. In this way, the magnet and the detector opposing to each other are positioned. As a result, when a vehicle switch is assembled, the variation in position of the magnet and detector is reduced. Accordingly, the vehicle switch is enhanced in switching accuracy and becomes capable of reliable operation.