Patents by Inventor Naoko Nishizawa
Naoko Nishizawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9309532Abstract: According to the present invention, a transformant and a gene-disrupted strain are provided which exhibit growth superior to that of ordinary plants in calcareous soil, and which can accumulate iron and zinc in large quantities in both calcareous soil and good soil; also provided are a gene, vector, protein, and antibody used for constructing these, and a method of construction, a composition for construction, a kit for construction, and a breeding method for a plant with improved iron deficiency tolerance, and enhanced iron and zinc accumulation in an edible part.Type: GrantFiled: July 19, 2013Date of Patent: April 12, 2016Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCYInventors: Takanori Kobayashi, Naoko Nishizawa
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Publication number: 20150299722Abstract: According to the present invention, a transformant and a gene-disrupted strain are provided which exhibit growth superior to that of ordinary plants in calcareous soil, and which can accumulate iron and zinc in large quantities in both calcareous soil and good soil; also provided are a gene, vector, protein, and antibody used for constructing these, and a method of construction, a composition for construction, a kit for construction, and a breeding method for a plant with improved iron deficiency tolerance, and enhanced iron and zinc accumulation in an edible part.Type: ApplicationFiled: July 19, 2013Publication date: October 22, 2015Applicant: Japan Science and Technology AgencyInventors: Takanori Kobayashi, Naoko Nishizawa
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Publication number: 20140259233Abstract: Provided are a transporter gene involved in the promotion or inhibition of Cd absorption by roots, a mutant gene thereof and a transporter protein thereof, as well as a rice plant in which Cd absorption is inhibited and a method for selecting and raising a Cd absorption-inhibiting rice plant, which are a gene encoding a transporter protein involved in the regulation of cadmium absorption, which contains the DNA nucleotide sequence shown in SEQ ID NO:2, a gene encoding a transporter protein involved in the regulation of cadmium absorption, which contains the DNA nucleotide sequence shown in SEQ ID NO:3, a gene encoding a transporter protein involved in the regulation of cadmium absorption, which contains the DNA nucleotide sequence shown in SEQ ID NO:4, and a transporter protein involved in the regulation of cadmium absorption, which contains the amino acid sequence of SEQ ID NO:1.Type: ApplicationFiled: October 23, 2012Publication date: September 11, 2014Applicant: NATIONAL INSTITUTE FOR AGRO-ENVIRONMENTAL SCIENCESInventors: Satoru Ishikawa, Masato Kuramata, Tadashi Abe, Masato Igura, Hiromi Nakanishi, Naoko Nishizawa
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Patent number: 8361968Abstract: The present invention provides a metastin derivative in which the amino acids comprising metastin were modified by alternative chemical substituents resulting in metastin derivitives, having excellent blood stability and exhibiting cancer metastasis inhibiting action or cancer growth inhibiting action.Type: GrantFiled: June 29, 2011Date of Patent: January 29, 2013Assignee: Takeda Pharmaceutical Company LimitedInventors: Chieko Kitada, Taiji Asami, Naoko Nishizawa, Tetsuya Ohtaki, Naoki Tarui, Hirokazu Matsumoto
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Patent number: 8207401Abstract: The present invention provides a polypeptide which binds to a cis-element in the vicinity of a gene related to an iron-acquisition mechanism. The polypeptide can increase expression of the gene related to the iron-acquiring mechanism. This makes it possible to obtain a plant improved in tolerance to iron deficiency.Type: GrantFiled: April 24, 2008Date of Patent: June 26, 2012Assignee: Japan Science and Technology AgencyInventors: Naoko Nishizawa, Satoshi Mori, Takanori Kobayashi, Yuko Ogo
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Publication number: 20120015868Abstract: The present invention provides a metastin derivative in which the amino acids comprising metastin were modified by alternative chemical substituents resulting in metastin derivitives, having excellent blood stability and exhibiting cancer metastasis inhibiting action or cancer growth inhibiting action.Type: ApplicationFiled: June 29, 2011Publication date: January 19, 2012Applicant: Takeda Pharmaceutical Company LimitedInventors: Chieko Kitada, Taiji Asami, Naoko Nishizawa, Tetsuya Ohtaki, Naoki Tarui, Hirokazu Matsumoto, Jiro Noguchi, Hisanori Matsui
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Publication number: 20110138496Abstract: The present invention provides a polypeptide which binds to a cis-element in the vicinity of a gene related to an iron-acquisition mechanism. The polypeptide can increase expression of the gene related to the iron-acquiring mechanism. This makes it possible to obtin a plant improved in tolerance to iron deficiency.Type: ApplicationFiled: April 24, 2008Publication date: June 9, 2011Inventors: Naoko Nishizawa, Satoshi Mori, Takanori Kobayashi, Yuko Ogo
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Publication number: 20090318365Abstract: The present invention provides a metastin derivative in which the amino acids comprising metastin were modified by alternative chemical substituents resulting in metastin derivatives, having excellent blood stability and exhibiting cancer metastasis inhibiting action or cancer growth inhibiting action.Type: ApplicationFiled: June 2, 2009Publication date: December 24, 2009Applicant: Takeda Pharmaceutical Company LimitedInventors: Chieko Kitada, Taiji Asami, Naoko Nishizawa, Tetsuya Ohtaki, Naoki Tarui, Hirokazu Matsumoto, Jiro Noguchi, Hisanori Matsui
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Patent number: 7604972Abstract: A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined. This gene is employed in constructing plants, in particular, grass plants highly tolerant to iron-deficiency. A nicotianamine synthase involved in the mugineic acid biosynthesis pathway; the amino acid sequence thereof; a gene encoding the same; a vector containing this gene; cells transformed by the vector; a process for producing nicotianamine by using the same; plants transformed by the gene encoding the nicotianamine synthase; and an antibody against the nicotianamine syntase.Type: GrantFiled: February 5, 2007Date of Patent: October 20, 2009Assignee: Japan Science and Technology CorporationInventors: Satoshi Mori, Kyoko Higuchi, Kazuya Suzuki, Naoko Nishizawa, Hiromi Nakanishi
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Publication number: 20080233627Abstract: A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined. This gene is employed in constructing plants, in particular, grass plants highly tolerant to iron-deficiency. A nicotianamine synthase involved in the mugineic acid biosynthesis pathway; the amino acid sequence thereof; a gene encoding the same; a vector containing this gene; cells transformed by the vector; a process for producing nicotianamine by using the same; plants transformed by the gene encoding the nicotianamine synthase; and an antibody against the nicotianamine syntase.Type: ApplicationFiled: February 5, 2007Publication date: September 25, 2008Applicant: Japan Science and Technology CorporationInventors: Satoshi Mori, Kyoko Higuchi, Kazuya Suzuki, Naoko Nishizawa, Hiromi Nakanishi
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Patent number: 7396668Abstract: A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined. This gene is employed in constructing plants, in particular, grass plants highly tolerant to iron deficiency. A nicotianamine synthase involved in the mugineic acid biosynthesis pathway; the amino acid sequence thereof; a gene encoding the same; a vector containing this gene; cells transformed by the vector; a process for producing nicotianamine by using the same; plants transformed by the gene encoding the nicotianamine synthase; and an antibody against the nicotianamine syntase.Type: GrantFiled: February 5, 2007Date of Patent: July 8, 2008Assignee: Japan Science and Technology AgencyInventors: Satoshi Mori, Kyoko Higuchi, Kazuya Suzuki, Naoko Nishizawa, Hiromi Nakanishi
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Patent number: 7259292Abstract: A method for producing transgenic gramineae plants having tolerance to iron deficiency by transforming the plants with a barley gene encoding nicotianamine aminotransferase (NAAT) and transgenic gramineae plants are provided. The present invention also provides transgenic gramineae plants having resistance to iron deficiency which can grow in iron deficiency and calcareous alkaline soils.Type: GrantFiled: July 4, 2000Date of Patent: August 21, 2007Assignee: Japan Science and Technology AgencyInventors: Satoshi Mori, Hiromi Nakanishi, Michiko Takahashi, Naoko Nishizawa
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Publication number: 20070150981Abstract: A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined. This gene is employed in constructing plants, in particular, grass plants highly tolerant to iron-deficiency. A nicotianamine synthase involved in the mugineic acid biosynthesis pathway; the amino acid sequence thereof; a gene encoding the same; a vector containing this gene; cells transformed by the vector; a process for producing nicotianamine by using the same; plants transformed by the gene encoding the nicotianamine synthase; and an antibody against the nicotianamine syntase.Type: ApplicationFiled: February 5, 2007Publication date: June 28, 2007Applicant: Japan Science and Technology CorporationInventors: Satoshi Mori, Kyoko Higuchi, Kazuya Suzuki, Naoko Nishizawa, Hiromi Nakanishi
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Patent number: 7192755Abstract: A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined. This gene is employed in constructing plants, in particular, grass plants highly tolerant to iron deficiency. A nicotianamine synthase involved in the mugineic acid biosynthesis pathway; the amino acid sequence thereof; a gene encoding the same; a vector containing this gene; cells transformed by the vector; a process for producing nicotianamine by using the same; plants transformed by the gene encoding the nicotianamine synthase; and an antibody against the nicotianamine syntase.Type: GrantFiled: April 30, 1999Date of Patent: March 20, 2007Assignee: Japan Science and Technology CorporationInventors: Satoshi Mori, Kyoko Higuchi, Kazuya Suzuki, Naoko Nishizawa, Hiromi Nakanishi
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Patent number: 7157260Abstract: A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined. This gene is employed in constructing plants, in particular, grass plants highly tolerant to iron deficiency. A nicotianamine synthase involved in the mugineic acid biosynthesis pathway; the amino acid sequence thereof; a gene encoding the same; a vector containing this gene; cells transformed by the vector; a process for producing nicotianamine by using the same; plants transformed by the gene encoding the nicotianamine synthase; and an antibody against the nicotianamine syntase.Type: GrantFiled: October 25, 2002Date of Patent: January 2, 2007Assignee: Japan Science & Technology AgencyInventors: Satoshi Mori, Kyoko Higuchi, Kazuya Suzuki, Naoko Nishizawa, Hiromi Nakanishi
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Publication number: 20040093634Abstract: A reductase reducing keto-nicotianamine into 2′-deoxymugineic acid in the course of the biosynthesis of mugineic acids participating in the iron-acquisition mechanism in plants; a gene encoding this enzyme; a plant having a enhanced tolerance to iron-deficiency owing to the above gene transferred thereinto; and enzyme kits and gene kits for constructing a plant having a enhanced tolerance to iron-deficiency which comprise enzymes for biosynthesizing mugineic acids participating in the iron-acquisition mechanism in plants or genes encoding these enzymes.Type: ApplicationFiled: April 18, 2003Publication date: May 13, 2004Inventors: Naoko Nishizawa, Satoshi Mori, Takashi Negishi
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Publication number: 20030087410Abstract: A nicotianamine synthase is isolated and purified. Then the gene of this enzyme is cloned and the base sequence and amino acid sequence thereof are determined. This gene is employed in constructing plants, in particular, grass plants highly tolerant to iron deficiency. A nicotianamine synthase involved in the mugineic acid biosynthesis pathway; the amino acid sequence thereof; a gene encoding the same; a vector containing this gene; cells transformed by the vector; a process for producing nicotianamine by using the same; plants transformed by the gene encoding the nicotianamine synthase; and an antibody against the nicotianamine syntase.Type: ApplicationFiled: October 25, 2002Publication date: May 8, 2003Applicant: Japan Science and Technology CorporationInventors: Satoshi Mori, Kyoko Higuchi, Kazuya Suzuki, Naoko Nishizawa, Hiromi Nakanishi