Patents by Inventor Naoto Ohtani
Naoto Ohtani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250084422Abstract: A transformant obtained by introducing (a) a lactate dehydrogenase gene and/or (b) a malate/lactate dehydrogenase gene into a Hydrogenophilus bacterium efficiently produces lactic acid through use of carbon dioxide as a sole carbon source. Parageobacillus thermoglucosidasius ldh gene, Geobacillus kaustophilus ldh gene and Thermus thermophilus ldh gene of lactate dehydrogenases, and Thermus thermophilus mldh gene and Meiothermus ruber mldh-1 and mldh-2 genes of malate/lactate dehydrogenases are preferable in that they have good lactic acid production efficiency.Type: ApplicationFiled: November 5, 2024Publication date: March 13, 2025Applicant: Utilization of Carbon Dioxide Institute Co., Ltd.Inventors: Hideaki YUKAWA, Naoto OHTANI
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Publication number: 20250027096Abstract: The present disclosure provides a transformant obtained by introducing an aldehyde-alcohol dehydrogenase gene into a bacterium of the genus Hydrogenophilus.Type: ApplicationFiled: October 1, 2024Publication date: January 23, 2025Applicants: Utilization of Carbon Dioxide Institute Co., Ltd., The University of TokyoInventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
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Patent number: 12188025Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.Type: GrantFiled: May 11, 2023Date of Patent: January 7, 2025Assignees: Utilization of Carbon Dioxide Institute Co., Ltd., The University of TokyoInventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
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Patent number: 12188024Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.Type: GrantFiled: May 11, 2023Date of Patent: January 7, 2025Assignees: Utilization of Carbon Dioxide Institute Co., Ltd., The University of TokyoInventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
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Publication number: 20230340503Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.Type: ApplicationFiled: May 11, 2023Publication date: October 26, 2023Applicants: Utilization of Carbon Dioxide Institute Co., Ltd., The University of TokyoInventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
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Publication number: 20230340504Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.Type: ApplicationFiled: May 11, 2023Publication date: October 26, 2023Applicants: Utilization of Carbon Dioxide Institute Co., Ltd., The University of TokyoInventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
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Patent number: 11697817Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.Type: GrantFiled: June 25, 2018Date of Patent: July 11, 2023Assignees: UTILIZATION OF CARBON DIOXIDE INSTITUTE CO., LTD., THE UNIVERSITY OF TOKYOInventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
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Publication number: 20220290109Abstract: When lactate dehydrogenase gene and/or malate/lactate dehydrogenase gene is/are introduced into a Hydrogenophilus bacterium as well as one or more of the three lactic acid-utilizing enzyme genes on the genome of the Hydrogenophilus bacterium is/are disrupted, lactic acid-producing ability is remarkably increased. The inventors of the present invention have identified the three lactic acid-utilizing enzyme genes of the Hydrogenophilus bacterium. When lactate permease gene is further introduced into the recombinant, lactic acid-producing ability is further increased. The recombinant of the present invention effectively produces lactic acid using carbon dioxide as a sole carbon source, and therefore, it is able to efficiently produce the material of biodegradable plastics, while solving global warming caused by increased emissions of carbon dioxide.Type: ApplicationFiled: August 9, 2019Publication date: September 15, 2022Applicant: Utilization of Carbon Dioxide Institute Co., Ltd.Inventors: Hideaki Yukawa, Naoto Ohtani
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Publication number: 20210403928Abstract: A transformant obtained by introducing (a) a lactate dehydrogenase gene and/or (b) a malate/lactate dehydrogenase gene into a Hydrogenophilus bacterium efficiently produces lactic acid through use of carbon dioxide as a sole carbon source. Parageobacillus thermoglucosidasius ldh gene, Geobacillus kaustophilus ldh gene and Thermus thermophilus ldh gene of lactate dehydrogenases, and Thermus thermophilus mldh gene and Meiothermus ruber mldh-1 and mldh-2 genes of malate/lactate dehydrogenases are preferable in that they have good lactic acid production efficiency.Type: ApplicationFiled: November 30, 2018Publication date: December 30, 2021Applicant: Utilization of Carbon Dioxide Institute Co., Ltd.Inventors: Yukawa Hideaki, Naoto Ohtani
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Publication number: 20210403927Abstract: Hydrogenophilus bacterium which produces a mutant acetolactate synthase III small subunit formed of a mutant amino acid sequence having an amino acid substitution is able to effectively produce valine through use of carbon dioxide as a sole carbon source.Type: ApplicationFiled: December 12, 2018Publication date: December 30, 2021Applicant: Utilization of Carbon Dioxide Institute Co., Ltd.Inventors: Hideaki Yukawa, Naoto Ohtani
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Publication number: 20210108215Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.Type: ApplicationFiled: June 25, 2018Publication date: April 15, 2021Applicants: Utilization of Carbon Dioxide Institute Co., Ltd., The University of TokyoInventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
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Publication number: 20060232964Abstract: The present invention is made to realize (i) a lighting device capable of emitting uniform surface light having high luminance and a wide color reproduction range, and (ii) a liquid crystal display device including the lighting device. Such a lighting device of the present invention includes: (i) a GB lamp for emitting blue and green light; (ii) an RLED for emitting red light; and (iii) a light emitting section for irradiating, to outside, the light emitted from each of the GB lamp and the RLED. The light emitting section has an upper surface serving as a light emitting surface, and the GB lamp and the RLED are provided under the light emitting section. Further, the RLED is so provided as to emit the light in a direction that is not perpendicular to the light emitting surface.Type: ApplicationFiled: March 10, 2006Publication date: October 19, 2006Inventors: Kazunori Hoshi, Naoto Ohtani, Ichiroh Aoyagi, Atsushi Sekikawa