Patents by Inventor Naoto Ohtani

Naoto Ohtani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250084422
    Abstract: A transformant obtained by introducing (a) a lactate dehydrogenase gene and/or (b) a malate/lactate dehydrogenase gene into a Hydrogenophilus bacterium efficiently produces lactic acid through use of carbon dioxide as a sole carbon source. Parageobacillus thermoglucosidasius ldh gene, Geobacillus kaustophilus ldh gene and Thermus thermophilus ldh gene of lactate dehydrogenases, and Thermus thermophilus mldh gene and Meiothermus ruber mldh-1 and mldh-2 genes of malate/lactate dehydrogenases are preferable in that they have good lactic acid production efficiency.
    Type: Application
    Filed: November 5, 2024
    Publication date: March 13, 2025
    Applicant: Utilization of Carbon Dioxide Institute Co., Ltd.
    Inventors: Hideaki YUKAWA, Naoto OHTANI
  • Publication number: 20250027096
    Abstract: The present disclosure provides a transformant obtained by introducing an aldehyde-alcohol dehydrogenase gene into a bacterium of the genus Hydrogenophilus.
    Type: Application
    Filed: October 1, 2024
    Publication date: January 23, 2025
    Applicants: Utilization of Carbon Dioxide Institute Co., Ltd., The University of Tokyo
    Inventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
  • Patent number: 12188025
    Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.
    Type: Grant
    Filed: May 11, 2023
    Date of Patent: January 7, 2025
    Assignees: Utilization of Carbon Dioxide Institute Co., Ltd., The University of Tokyo
    Inventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
  • Patent number: 12188024
    Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.
    Type: Grant
    Filed: May 11, 2023
    Date of Patent: January 7, 2025
    Assignees: Utilization of Carbon Dioxide Institute Co., Ltd., The University of Tokyo
    Inventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
  • Publication number: 20230340503
    Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.
    Type: Application
    Filed: May 11, 2023
    Publication date: October 26, 2023
    Applicants: Utilization of Carbon Dioxide Institute Co., Ltd., The University of Tokyo
    Inventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
  • Publication number: 20230340504
    Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.
    Type: Application
    Filed: May 11, 2023
    Publication date: October 26, 2023
    Applicants: Utilization of Carbon Dioxide Institute Co., Ltd., The University of Tokyo
    Inventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
  • Patent number: 11697817
    Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: July 11, 2023
    Assignees: UTILIZATION OF CARBON DIOXIDE INSTITUTE CO., LTD., THE UNIVERSITY OF TOKYO
    Inventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
  • Publication number: 20220290109
    Abstract: When lactate dehydrogenase gene and/or malate/lactate dehydrogenase gene is/are introduced into a Hydrogenophilus bacterium as well as one or more of the three lactic acid-utilizing enzyme genes on the genome of the Hydrogenophilus bacterium is/are disrupted, lactic acid-producing ability is remarkably increased. The inventors of the present invention have identified the three lactic acid-utilizing enzyme genes of the Hydrogenophilus bacterium. When lactate permease gene is further introduced into the recombinant, lactic acid-producing ability is further increased. The recombinant of the present invention effectively produces lactic acid using carbon dioxide as a sole carbon source, and therefore, it is able to efficiently produce the material of biodegradable plastics, while solving global warming caused by increased emissions of carbon dioxide.
    Type: Application
    Filed: August 9, 2019
    Publication date: September 15, 2022
    Applicant: Utilization of Carbon Dioxide Institute Co., Ltd.
    Inventors: Hideaki Yukawa, Naoto Ohtani
  • Publication number: 20210403928
    Abstract: A transformant obtained by introducing (a) a lactate dehydrogenase gene and/or (b) a malate/lactate dehydrogenase gene into a Hydrogenophilus bacterium efficiently produces lactic acid through use of carbon dioxide as a sole carbon source. Parageobacillus thermoglucosidasius ldh gene, Geobacillus kaustophilus ldh gene and Thermus thermophilus ldh gene of lactate dehydrogenases, and Thermus thermophilus mldh gene and Meiothermus ruber mldh-1 and mldh-2 genes of malate/lactate dehydrogenases are preferable in that they have good lactic acid production efficiency.
    Type: Application
    Filed: November 30, 2018
    Publication date: December 30, 2021
    Applicant: Utilization of Carbon Dioxide Institute Co., Ltd.
    Inventors: Yukawa Hideaki, Naoto Ohtani
  • Publication number: 20210403927
    Abstract: Hydrogenophilus bacterium which produces a mutant acetolactate synthase III small subunit formed of a mutant amino acid sequence having an amino acid substitution is able to effectively produce valine through use of carbon dioxide as a sole carbon source.
    Type: Application
    Filed: December 12, 2018
    Publication date: December 30, 2021
    Applicant: Utilization of Carbon Dioxide Institute Co., Ltd.
    Inventors: Hideaki Yukawa, Naoto Ohtani
  • Publication number: 20210108215
    Abstract: A transformant obtained by introducing a DNA of (a1), (a2), or (a3) below, and (b) an alcohol dehydrogenase gene, into a bacterium of the genus Hydrogenophilus, can efficiently produce isobutanol utilizing carbon dioxide as a sole carbon source. (a1) DNA which consists of a base sequence of SEQ ID NO: 1; (a2) DNA which consists of a base sequence having 90% or more identity with SEQ ID NO: 1, the DNA encoding a polypeptide having 2-keto-acid decarboxylase activity; (a3) DNA which hybridizes with a DNA consisting of a base sequence complementary to SEQ ID NO: 1 under stringent conditions, and which encodes a polypeptide having 2-keto-acid decarboxylase activity.
    Type: Application
    Filed: June 25, 2018
    Publication date: April 15, 2021
    Applicants: Utilization of Carbon Dioxide Institute Co., Ltd., The University of Tokyo
    Inventors: Hideaki Yukawa, Naoto Ohtani, Masaharu Ishii
  • Publication number: 20060232964
    Abstract: The present invention is made to realize (i) a lighting device capable of emitting uniform surface light having high luminance and a wide color reproduction range, and (ii) a liquid crystal display device including the lighting device. Such a lighting device of the present invention includes: (i) a GB lamp for emitting blue and green light; (ii) an RLED for emitting red light; and (iii) a light emitting section for irradiating, to outside, the light emitted from each of the GB lamp and the RLED. The light emitting section has an upper surface serving as a light emitting surface, and the GB lamp and the RLED are provided under the light emitting section. Further, the RLED is so provided as to emit the light in a direction that is not perpendicular to the light emitting surface.
    Type: Application
    Filed: March 10, 2006
    Publication date: October 19, 2006
    Inventors: Kazunori Hoshi, Naoto Ohtani, Ichiroh Aoyagi, Atsushi Sekikawa