Abstract: A medical device may include an insertion device having a proximal end, a distal end, and a lumen extending therethrough. A snare device may be configured to transition between a retracted state within the lumen of the insertion device, and an extended state extending distally of the insertion device. The snare device may comprise a wire. A member may be disposed within the lumen of the insertion device. The member may be configured to maintain legs of the snare device in an open snare loop configuration in the extended state. In the open snare loop configuration, the wire may include an arcuate loop.

Abstract: A medical/surgical device for performing tissue resection can include an endoscope with proximal and distal ends, defining working channels, and a snare assembly located in one of the working channels. The working channel may include a bend near the distal end and towards the outward radial wall of the endoscope. The snare assembly may include a snare loop and an actuation element imparted with the pre-formed angular bends and an actuation control handle. The bends of the actuation element and the working channel may be the same. The rotational manipulation of the actuation element may synchronize the pre-formed bend of the actuation element with the bend of the working channel to concentrically (or otherwise) align the deployed snare loop with the endoscope or endoscope attachments.

Abstract: A tissue closure device includes a needle and a suture extending therefrom, a proximal head including a proximal slot and a proximal locking mechanism for releasably engaging a first end of the needle in the proximal slot in a first configuration, and a distal head movably coupled to the proximal head so that the proximal and distal heads are movable relative to one another between an open configuration, in which a target tissue is received therebetween, and a closed configuration, in which the target tissue gripped therebetween. The distal head includes a distal slot and a distal locking mechanism for releasably engaging a second end of the needle in the distal slot in a second configuration, the needle movable between the first and second configurations by rotating the needle, the needle alternatingly passed between the proximal and distal heads to thread the suture through the target tissue.

Abstract: Disclosed herein are devices and methods for introducing a plurality of instruments to a target site through a working channel. The working channel can include a surface adapted to guide one or more instruments into select positions. The working channel can be defined by a portion of a guide tube or tip that may be coupled with an endoscope.

Abstract: Disclosed herein are various systems and methods for guiding, supporting, and/or housing instruments. One exemplary system includes a guide tube having a manipulation section and mated with rails carrying instrument control members. Moving the rails with respect to the guide tube, or another point of reference, can control movement of the manipulation section.

Abstract: A medical/surgical device for performing tissue resection can include an endoscope with proximal and distal ends, defining working channels, and a snare assembly located in one of the working channels. The working channel may include a bend near the distal end and towards the outward radial wall of the endoscope. The snare assembly may include a snare loop and an actuation element imparted with the pre-formed angular bends and an actuation control handle. The bends of the actuation element and the working channel may be the same. The rotational manipulation of the actuation element may synchronize the pre-formed bend of the actuation element with the bend of the working channel to concentrically (or otherwise) align the deployed snare loop with the endoscope or endoscope attachments.

Abstract: A medical device may include a shaft, and a first tool extending from a distal end of the shaft. The medical device also may include a control assembly coupled to the shaft. The control assembly may include a console, a first grip extending proximally from the console, and a second grip extending proximally from the console. The control assembly also may include a first deflection actuator configured to deflect the first tool about a longitudinal axis of the first tool, a first rotation actuator configured to rotate the first tool about the longitudinal axis of the first tool, and a first longitudinal actuator configured to move the first tool along the longitudinal axis of the first tool.

Abstract: This invention is directed to a medical device having an elongate shaft having a distal end and a controller coupled to the shaft. A control member can extend through at least part of the elongate shaft and at least part of the controller, wherein the control member in a tensioned configuration can be moveable by the controller to control the distal end of the shaft and the control member can be slack in an untensioned configuration. A tensioning mechanism can be configured to move relative to at least one of the elongate shaft and the controller to tension the control member and automatically lock the control member in the tensioned configuration.

Abstract: A tissue closure device includes a needle and a suture extending therefrom, a proximal head including a proximal slot and a proximal locking mechanism for releasably engaging a first end of the needle in the proximal slot in a first configuration, and a distal head movably coupled to the proximal head so that the proximal and distal heads are movable relative to one another between an open configuration, in which a target tissue is received therebetween, and a closed configuration, in which the target tissue gripped therebetween. The distal head includes a distal slot and a distal locking mechanism for releasably engaging a second end of the needle in the distal slot in a second configuration, the needle movable between the first and second configurations by rotating the needle, the needle alternatingly passed between the proximal and distal heads to thread the suture through the target tissue.

Abstract: A system and method for treating tissue includes an applicator including a bushing and a control member. The control member extends through the bushing to an enlarged distal end. The system also includes clip assembly releasably coupleable to the applicator. The clip assembly includes clip arms and a yoke including a distal portion connected to the clip arms and a proximal portion. The proximal portion includes a slot configured to receive the enlarged distal end of the control member and at least one helical cut positioned at a proximal end of the slot. The helical cut is configured to rotate the enlarged distal end from a first orientation in which the enlarged distal end is offset from the slot to a second orientation in which the enlarged distal end is aligned with the slot so that when a force thereon exceeds a threshold value, the enlarged distal end passes into the slot.

Abstract: Disclosed herein are various systems and methods for guiding, supporting, and/or housing instruments. One exemplary system includes a guide tube having a manipulation section and mated with rails carrying instrument control members. Moving the rails with respect to the guide tube, or another point of reference, can control movement of the manipulation section.

Abstract: Disclosed herein are devices and methods for introducing a plurality of instruments to a target site through a working channel. The working channel can include a surface adapted to guide one or more instruments into select positions. The working channel can be defined by a portion of a guide tube or tip that may be coupled with an endoscope.

Abstract: A device for treating tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a lumen extending therein and a clip slidably received within the lumen of the capsule. The clip includes a middle prong, a first outer prong and a second outer prong. The first prong is coupled to the middle prong so that the first prong is movable relative to the middle prong between a first open configuration and a first closed configuration. The second outer prong coupled to the middle prong so that the second prong is movable relative to the middle prong between a second open configuration and a second closed configuration. The first and second outer prongs are independently movable relative to the middle prong to be moved between the first and second open configurations to the first and second open configurations and the first and second closed configurations.

Abstract: A medical device may include a shaft, and a first tool extending from a distal end of the shaft. The medical device also may include a control assembly coupled to the shaft. The control assembly may include a console, a first grip extending proximally from the console, and a second grip extending proximally from the console. The control assembly also may include a first deflection actuator configured to deflect the first tool about a longitudinal axis of the first tool, a first rotation actuator configured to rotate the first tool about the longitudinal axis of the first tool, and a first longitudinal actuator configured to move the first tool along the longitudinal axis of the first tool.

Abstract: This invention is directed to a medical device having an elongate shaft having a distal end and a controller coupled to the shaft. A control member can extend through at least part of the elongate shaft and at least part of the controller, wherein the control member in a tensioned configuration can be moveable by the controller to control the distal end of the shaft and the control member can be slack in an untensioned configuration. A tensioning mechanism can be configured to move relative to at least one of the elongate shaft and the controller to tension the control member and automatically lock the control member in the tensioned configuration.

Abstract: A system for treating tissue includes a clip assembly having a pair of clip arms. Proximal ends of the clip arms engage a distal portion of a central member slidably received within a channel of a capsule to be moved between an open configuration and a closed configuration. The central member includes the distal portion and a proximal portion connected to one another via a releasable connection which releases when subject to a force exceeding a predetermined threshold level. The system also includes an applicator releasably coupled to the clip assembly. The applicator includes an outer sleeve through which a control member extends. A distal end of the control member engages a cavity of the proximal portion to move the central member relative to the capsule. A lumen of the outer sleeve is sized and shaped to slidably receive the capsule therein.

Abstract: A device for treating tissue includes a capsule extending longitudinally from a proximal end to a distal end and including a lumen extending therein and a clip slidably received within the lumen of the capsule. The clip includes a middle prong, a first outer prong and a second outer prong. The first prong is coupled to the middle prong so that the first prong is movable relative to the middle prong between a first open configuration and a first closed configuration. The second outer prong coupled to the middle prong so that the second prong is movable relative to the middle prong between a second open configuration and a second closed configuration. The first and second outer prongs are independently movable relative to the middle prong to be moved between the first and second open configurations to the first and second open configurations and the first and second closed configurations.

Abstract: This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device may include a medical device for delivery of a surgical closure member. The medical device includes an elongate tubular member having a proximal end, a distal end and a lumen extending therein. The elongate tubular member is adapted to be delivered through the working channel of an endoscope and the lumen is adapted to receive a surgical closure member. The medical device also includes a tissue support extending from the distal end of the elongate tubular member. The tissue support includes a support surface and the support surface is adapted to support tissue as a surgical closure member engages the tissue thereon.

Abstract: In accordance with an aspect of the present disclosure, the medical device includes a snare member having a proximal portion and a distal portion. The medical device also includes an operating member extending proximally of the snare member. The operating is enabled to extend and retract the snare member from a sheath. The snare member includes a transition portion extending between the proximal portion and the distal portion. The transition portion connects the proximal portion to the distal portion. The distal portion has a different cross-sectional area than the proximal section of the snare member.

Abstract: A device for passing a needle and suture longitudinally through a target tissue includes a proximal jaw including a proximal recess and a proximal retention mechanism for releasably engaging a first end of a needle received within the proximal recess and a distal jaw movably coupled to the proximal jaw such that the proximal and distal jaws are longitudinally movable relative to one another. The distal jaw includes a distal recess and a distal retention mechanism for releasably engaging a second end of the needle received within the distal recess. The proximal and distal jaws are movable between a first state, in which the proximal retention mechanism is in a locked configuration and the distal retention mechanism is in an unlocked configuration, and a second state, in which the proximal retention mechanism is in an unlocked configuration and the distal retention mechanism is in a locked configuration.