Patents by Inventor Naweed Muhammad

Naweed Muhammad has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10442826
    Abstract: The present invention provides water-soluble acetaminophen prodrugs and formulations which may be suitable for parenteral administration. Methods of treating a disease or condition responsive to acetaminophen (such as fever and/or pain) using the acetaminophen prodrugs, as well as kits, unit dosages, and combinations with additional pharmaceutical agent(s) are also provided.
    Type: Grant
    Filed: April 25, 2018
    Date of Patent: October 15, 2019
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Naweed Muhammad, Keith R. Bley
  • Patent number: 10377779
    Abstract: The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
    Type: Grant
    Filed: May 10, 2017
    Date of Patent: August 13, 2019
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Naweed Muhammad, Keith R. Bley
  • Publication number: 20190092795
    Abstract: The present invention provides water-soluble acetaminophen prodrugs and formulations which may be suitable for parenteral administration. Methods of treating a disease or condition responsive to acetaminophen (such as fever and/or pain) using the acetaminophen prodrugs, as well as kits, unit dosages, and combinations with additional pharmaceutical agent(s) are also provided.
    Type: Application
    Filed: April 25, 2018
    Publication date: March 28, 2019
    Inventors: Naweed MUHAMMAD, Keith R. BLEY
  • Publication number: 20190062273
    Abstract: The present invention provides hepatoprotectant acetaminophen mutual prodrugs, which have an acetaminophen moiety covalently linked to a second moiety that may act as a hepatoprotectant against acetaminophen hepatotoxicity. Additionally, acetaminophen mutual prodrugs may have improved water solubility which may provide better suitability for parenteral and other dosage forms relative to administration of acetaminophen. Also provided are methods of treating a disease or condition that is responsive to acetaminophen (such as fever, pain and ischemic injury) using hepatoprotectant acetaminophen mutual prodrugs, as well as kits and unit dosages.
    Type: Application
    Filed: March 15, 2018
    Publication date: February 28, 2019
    Inventors: Naweed MUHAMMAD, Keith R. BLEY, Jeffrey TOBIAS
  • Publication number: 20180169039
    Abstract: Compositions are provided that contain a TRPV1 agonist, such as capsaicin, and a solvent system. Topical application of the composition results in rapid delivery of agonist to the dermis and epidermis. Method of using the compositions for reducing nociceptive nerve fiber function in subjects, and for treatment of capsaicin-responsive conditions are also provided.
    Type: Application
    Filed: August 1, 2017
    Publication date: June 21, 2018
    Inventors: Naweed MUHAMMAD, Gene Curtis JAMIESON, Keith R. BLEY, Sanjay CHANDA
  • Patent number: 9981998
    Abstract: The present invention provides water-soluble acetaminophen prodrugs and formulations which may be suitable for parenteral administration. Methods of treating a disease or condition responsive to acetaminophen (such as fever and/or pain) using the acetaminophen prodrugs, as well as kits, unit dosages, and combinations with additional pharmaceutical agent(s) are also provided.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: May 29, 2018
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Naweed Muhammad, Keith R. Bley
  • Patent number: 9951001
    Abstract: The present invention provides hepatoprotectant acetaminophen mutual prodrugs, which have an acetaminophen moiety covalently linked to a second moiety that may act as a hepatoprotectant against acetaminophen hepatotoxicity. Additionally, acetaminophen mutual prodrugs may have improved water solubility which may provide better suitability for parenteral and other dosage forms relative to administration of acetaminophen. Also provided are methods of treating a disease or condition that is responsive to acetaminophen (such as fever, pain and ischemic injury) using hepatoprotectant acetaminophen mutual prodrugs, as well as kits and unit dosages.
    Type: Grant
    Filed: May 9, 2016
    Date of Patent: April 24, 2018
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Naweed Muhammad, Keith R. Bley, Jeffrey Tobias
  • Publication number: 20180086778
    Abstract: The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
    Type: Application
    Filed: May 10, 2017
    Publication date: March 29, 2018
    Inventors: Naweed MUHAMMAD, Keith R. BLEY
  • Publication number: 20170312214
    Abstract: The invention provides compositions, methods and kits for the removal of harmful or irritating substances from bodily surfaces. Kits may include a composition containing capsaicin and a capsaicin-cleansing composition, e.g., a composition in which capsaicin is soluble.
    Type: Application
    Filed: December 13, 2016
    Publication date: November 2, 2017
    Inventors: Arturo J. ANGEL, Larry W. LITLE, Keith R. BLEY, Allan L. WILCOX, Gene Curtis JAMIESON, Naweed MUHAMMAD
  • Patent number: 9750707
    Abstract: Compositions are provided that contain a TRPV1 agonist, such as capsaicin, and a solvent system. Topical application of the composition results in rapid delivery of agonist to the dermis and epidermis. Method of using the compositions for reducing nociceptive nerve fiber function in subjects, and for treatment of capsaicin-responsive conditions are also provided.
    Type: Grant
    Filed: April 17, 2014
    Date of Patent: September 5, 2017
    Assignee: ACORDA THERAPEUTICS, INC.
    Inventors: Naweed Muhammad, Gene Curtis Jamieson, Keith R. Bley, Sanjay Chanda
  • Patent number: 9683000
    Abstract: The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: June 20, 2017
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Naweed Muhammad, Keith R. Bley
  • Patent number: 9549893
    Abstract: The invention provides compositions, methods and kits for the removal of harmful or irritating substances from bodily surfaces. Kits may include a composition containing capsaicin and a capsaicin-cleansing composition, e.g., a composition in which capsaicin is soluble.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: January 24, 2017
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Arturo J. Angel, Larry W. Litle, Keith R. Bley, Allan L. Wilcox, Gene C. Jamieson, Naweed Muhammad
  • Publication number: 20170008916
    Abstract: The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
    Type: Application
    Filed: February 5, 2016
    Publication date: January 12, 2017
    Inventors: Naweed Muhammad, Keith R. BLEY
  • Publication number: 20160326107
    Abstract: The present invention provides hepatoprotectant acetaminophen mutual prodrugs, which have an acetaminophen moiety covalently linked to a second moiety that may act as a hepatoprotectant against acetaminophen hepatotoxicity. Additionally, acetaminophen mutual prodrugs may have improved water solubility which may provide better suitability for parenteral and other dosage forms relative to administration of acetaminophen. Also provided are methods of treating a disease or condition that is responsive to acetaminophen (such as fever, pain and ischemic injury) using hepatoprotectant acetaminophen mutual prodrugs, as well as kits and unit dosages.
    Type: Application
    Filed: May 9, 2016
    Publication date: November 10, 2016
    Inventors: Naweed MUHAMMAD, Keith R. BLEY, Jeffrey TOBIAS
  • Publication number: 20160264605
    Abstract: The present invention provides water-soluble acetaminophen prodrugs and formulations which may be suitable for parenteral administration. Methods of treating a disease or condition responsive to acetaminophen (such as fever and/or pain) using the acetaminophen prodrugs, as well as kits, unit dosages, and combinations with additional pharmaceutical agent(s) are also provided.
    Type: Application
    Filed: March 22, 2016
    Publication date: September 15, 2016
    Inventors: Naweed MUHAMMAD, Keith R. BLEY
  • Patent number: 9289501
    Abstract: The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
    Type: Grant
    Filed: February 23, 2015
    Date of Patent: March 22, 2016
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Naweed Muhammad, Keith R. Bley
  • Publication number: 20160024126
    Abstract: The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
    Type: Application
    Filed: February 23, 2015
    Publication date: January 28, 2016
    Inventors: Naweed Muhammad, Keith R. Bley
  • Publication number: 20150104498
    Abstract: The invention provides compositions, methods and kits for the removal of harmful or irritating substances from bodily surfaces. Kits may include a composition containing capsaicin and a capsaicin-cleansing composition, e.g., a composition in which capsaicin is soluble.
    Type: Application
    Filed: November 14, 2014
    Publication date: April 16, 2015
    Inventors: Arturo J. ANGEL, Larry W. LITLE, Keith R. BLEY, Allan L. WILCOX, Gene C. JAMIESON, Naweed MUHAMMAD
  • Patent number: 8993545
    Abstract: The present invention provides carbonate prodrugs which comprise a carbonic phosphoric anhydride prodrug moiety attached to the hydroxyl or carboxyl group of a parent drug moiety. The prodrugs may provide improved physicochemical properties over the parent drug. Also provided are methods of treating a disease or condition that is responsive to the parent drug using the carbonate prodrugs, as well as kits and unit dosages.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: March 31, 2015
    Assignee: Acorda Therapeutics, Inc.
    Inventors: Naweed Muhammad, Keith R. Bley
  • Publication number: 20150073056
    Abstract: Compositions are provided that contain a TRPV1 agonist, such as capsaicin, and a solvent system. Topical application of the composition results in rapid delivery of agonist to the dermis and epidermis. Method of using the compositions for reducing nociceptive nerve fiber function in subjects, and for treatment of capsaicin-responsive conditions are also provided.
    Type: Application
    Filed: April 17, 2014
    Publication date: March 12, 2015
    Applicant: ACORDA THERAPEUTICS, INC.
    Inventors: Naweed MUHAMMAD, Gene Curtis JAMIESON, Keith R. BLEY, Sanjay CHANDA