Abstract: A device and system for an automatic robot, drone, and/or courier to deliver, hold, protect, and return parcels. The multi-user system has DRONEDEK docking features and include a small footprint combination; nine to 400 parcel capacity; has a multi-belt conveyor and turntables for parcels; uses omni-directional and cross roller turns; is compatible with re-usable packaging; has a parcel tilt and reload for return packages; utilizes a lightweight frame; has secure outer skin and access panels for maintenance; communicates and is controlled by DRONEDEK docking station; can use robotic unload/pick and place, multiple delivery/receiving, and can attach to other third-party parcel systems. A multi-user box is quite simply a unit with the functionality of one or more DRONEDEK docking stations and features numerous/multiple pigeonholes and container spaces for safe, secure storage of items to separate and distinct users in a bulk location.

Abstract: A miniaturized astrometric alignment sensor may detect stellar objects and targets from which both stellar and object tracking are performed. The sensor may search for one or more bright opens in an image captured by a camera of a space vehicle, and determine if the one or more bright objects is a genuine star or a secondary element. The sensor may also catalog entries of identified stars after three or more bright objects are determined to be genuine stars, and display the cataloged entries of the identified stars, wherein the cataloged entries comprises positional and velocity of the space vehicle in relation of the identified stars and a sensor body reference frame.

Abstract: In a method of placing a security trade order using a trading algorithm in a computerized trading system, candidate order characteristics of a candidate order are received through a first GUI, and current market characteristics are obtained. Performance and fill rate scores are forecasted for executions of the candidate order by each of a plurality of trading algorithms using a ranking model based on historical data for a plurality of orders previously-executed via one or more of the plurality of trading algorithms, the candidate order characteristics and the current market characteristics. Each of the plurality of trading algorithms are ranked for the candidate order. A highest ranked trading algorithm is selected and is displayed on a second GUI. A selection of one of the displayed highest ranked trading algorithm is received from a user, and the candidate order is placed using the selected trading algorithm.

Abstract: The present invention relates to a space-based instrument which provides continuous coronal electron temperature and velocity images, for a predetermined period of time, thereby improving the understanding of coronal evolution and how the solar wind and Coronal Mass Ejection transients evolve from the low solar atmosphere through the heliosphere for an entire solar rotation. Specifically, the present invention relates to using a 6U spherical occulter coronagraph CubeSat, and a relative navigational system (RNS) that controls the position of the spacecraft relative to the occulting sphere. The present invention innovatively deploys a free-flying spherical occulter, and after deployment, the actively controlled CubeSat will provide an inertial formation flying with the spherical occulter and Sun.

Abstract: The present invention relates to a space-based instrument which provides continuous coronal electron temperature and velocity images, for a predetermined period of time, thereby improving the understanding of coronal evolution and how the solar wind and Coronal Mass Ejection transients evolve from the low solar atmosphere through the heliosphere for an entire solar rotation. Specifically, the present invention relates to using a 6U spherical occulter coronagraph CubeSat, and a relative navigational system (RNS) that controls the position of the spacecraft relative to the occulting sphere. The present invention innovatively deploys a free-flying spherical occulter, and after deployment, the actively controlled CubeSat will provide an inertial formation flying with the spherical occulter and Sun.

Abstract: The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

Abstract: The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

Abstract: Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.

Abstract: Disclosed are compounds of the formula: where variables Q, Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.

Abstract: The invention relates to acetyl 2-hydroxy-1,3-diaminospirocyclohexanes and derivatives thereof that are useful in treating at least one disease, disorder, and condition associated with amyloidosis. Amyloidosis refers to a collection of diseases, disorders, and condition associated with abnormal deposition of A-beta protein.

Abstract: The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.

Abstract: The invention relates to novel compounds and also to methods of treating at least one disease, disorder, or condition associated with amyloidosis using such compounds. Amyloidosis refers to a collection of diseases, disorders, and conditions associated with abnormal deposition of A-beta protein.