Patents by Inventor Neil Alexander MCDONALD

Neil Alexander MCDONALD has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecular probes for detecting gram-negative bacteria in vitro and in vivo
    Patent number: 10648979
    Abstract: A probe is provided comprising a label and a binding moiety, wherein the binding moiety is adapted to bind to gram-negative bacteria, and to substantially not bind to animal cells or gram-positive bacteria. A method of detecting the presence of bacteria in a target area is also provided, which allows the detection of bacteria generally, and the determination of whether that bacteria is gram negative or gram positive.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: May 12, 2020
    Assignee: The University Court of the University of Edinburgh
    Inventors: Mark Bradley, Annamaria Helena Lilienkampf, Nikolaos Avlonitis, Marc Vendrell Escobar, Neil Alexander McDonald, Christopher Haslett, Kanwaldeep Dhaliwal, Timothy Simon Walsh
  • Fluorescent polybranched probes for detecting bacteria and/or fungi in vitro and in vivo
    Patent number: 10520504
    Abstract: A probe for detecting bacteria and/or fungi in vitro and in vivo is provided, the probe having a core and a plurality of probe elements; each probe element within the plurality of probe elements extending from the core and having a fluorophore and a binding moiety, wherein the binding moiety is a bacteria binding moiety and selectively binds to bacteria and/or to fungi and not to animal cells. Methods of use of the probe and kits comprising the probe are also provided.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: December 31, 2019
    Assignee: The University Court of the University of Edinburgh
    Inventors: Mark Bradley, Annamaria Helena Lilienkampf, Nikolaos Avlonitis, Marc Vendrell Escobar, Neil Alexander McDonald, Christopher Haslett, Kanwaldeep Dhaliwal, Timothy Simon Walsh
  • MOLECULAR PROBES FOR DETECTING GRAM-NEGATIVE BACTERIA IN VITRO AND IN VIVO
    Publication number: 20180231548
    Abstract: A probe is provided comprising a label and a binding moiety, Deliver First Probe wherein the binding moiety is adapted to bind to gram-negative bacteria, and to Target Area to substantially not bind to animal cells or gram-positive bacteria. A method of detecting the presence of bacteria in a target area is also provided, which allows the detection of bacteria generally, and the determination of whether that bacteria is gram negative or gram positive.
    Type: Application
    Filed: November 13, 2015
    Publication date: August 16, 2018
    Inventors: Mark BRADLEY, Annamaria Helena LILIENKAMPF, Nikolaos AVLONITIS, Marc Vendrell ESCOBAR, Neil Alexander MCDONALD, Christopher HASLETT, Kanwaldeep DHALIWAL, Timothy Simon WALSH
  • FLUORESCENT POLYBRANCHED PROBES FOR DETECTING BACTERIA AND/OR FUNGI IN VITRO AND IN VIVO
    Publication number: 20180120314
    Abstract: A probe is provided comprising a core and a plurality of probe elements; each probe element within the plurality of probe elements extending from the core and comprising a fluorophore and a binding moiety. Methods of use of the probe and kits comprising the probe are also provided.
    Type: Application
    Filed: November 13, 2015
    Publication date: May 3, 2018
    Inventors: Mark BRADLEY, Annamaria Helena LILIENKAMPF, Nikolaos AVLONITIS, Marc Vendrell ESCOBAR, Neil Alexander MCDONALD, Christopher HASLETT, Kanwaldeep DHALIWAL, Timothy Simon WALSH