Patents by Inventor Neil James Fraser

Neil James Fraser has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified chemokine receptor ccr-3 and assay
    Publication number: 20030157639
    Abstract: The present invention relates to the modification of the CC chemokine receptor 3 to stabilise or enhance surface expression, for example, to reduce internalization and/or kinase-mediated phosphorylation. The invention also relates to assays for CCR3 receptor activity in which internalization and/or kinase mediated phosphorylation of the receptor is reduced.
    Type: Application
    Filed: April 25, 2003
    Publication date: August 21, 2003
    Inventors: Ashley Antony Barnes, Neil James Fraser, Celestine Theresa O'Shaughnessy, Alan Wise
  • Novel receptor
    Publication number: 20030082801
    Abstract: The present invention relates to the novel GABAB receptor subtypes GABAB-R1c and GABAB-R2 as well as to a novel, functional GABAB receptor which comprises a heterodimer of GABAB-R1 and GABAB-R2 receptor subunits. The present invention also relates to variants of the receptors, nucleotide sequences encoding the receptors and variants thereof and novel vectors, stable cell lines, antibodies, screening methods, methods of treatment and methods of receptor production.
    Type: Application
    Filed: November 20, 2002
    Publication date: May 1, 2003
    Inventors: Ashley Anthony Barnes, Alan Wise, Fiona Hamilton Marshall, Neil James Fraser, Julia Helen Margaret White, Steven Michael Foord
  • Receptor
    Patent number: 6518399
    Abstract: The present invention relates to the novel GABAB receptor subtypes GABAB-R1c and GABAB-R2 as well as to a novel, functional GABAB receptor which comprises a heterodimer of GABAB-R1 and GABAB-R2 receptor subunits. The present invention also relates to variants of the receptors, nucleotide sequences encoding the receptors and variants thereof and novel vectors, stable cell lines, antibodies, screening methods, methods of treatment and methods of receptor production.
    Type: Grant
    Filed: September 3, 1999
    Date of Patent: February 11, 2003
    Assignee: Smithkline Beecham Corporation
    Inventors: Ashley Antony Barnes, Alan Wise, Fiona Hamilton Marshall, Neil James Fraser, Julia Helen Margaret White, Steven Michael Foord