Patents by Inventor Neil O'BRIEN

Neil O'BRIEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ERK INHIBITORS AND USES THEREOF
    Publication number: 20220002294
    Abstract: The present disclosure provides compounds and compositions that are inhibitors of ERK1, ERK2, or both, and methods of use thereof.
    Type: Application
    Filed: November 15, 2019
    Publication date: January 6, 2022
    Inventors: Corey M. Reeves, Brandan M. O'Boyle, Justin A. Hilf, Dylan Conklin, Martina S. McDermott, Neil A. O'Brien, Michael J. Palazzolo, Dennis Slamon, Steven J. Wittenberger, Oliver C. Loson, Michael D. Bartberger, Brian M. Stoltz
  • CLAUDIN6 ANTIBODIES AND METHODS OF TREATING CANCER
    Publication number: 20200291111
    Abstract: The present disclosure provides antigen-binding proteins which bind to Claudin-6 (CLDN6). In various aspects, the antigen-binding proteins bind to Extracellular Loop 2 (EL2) of the extracellular domain of CLDN6. Related polypeptides, nucleic acids, vectors, host cells, and conjugates are further provided herein. Kits and pharmaceutical compositions comprising such entities are moreover provided. Also provided are methods of making an antigen-binding protein and methods of treating a subject having cancer.
    Type: Application
    Filed: September 18, 2018
    Publication date: September 17, 2020
    Inventors: Dylan Conklin, Dennis Slamon, Neil A. O'Brien, Michael J. Palazzolo, Erika Von Euw
  • Synthetic peptides containing protective epitopes for the treatment and prevention of periodontitis associated with Porphyromonas gingivalis
    Publication number: 20050169853
    Abstract: This invention relates to a peptide selected from the group: FLLDADHNTFGSVIPATGPLFTGTASS LYSANFESLIPANADPVVT-TQNIIVTG LYSANFEYLIPANADPVVTTQNIJVTG TNPEPASGKMWIAGDGGNQP RYDDFTFEAGKKYTFTMRRAGMGDGTD DDYVFEAGKKYHFLLLMKKMGSGDGTE TNPEPASGKMWIAGDGGNQPARYDDFTFEAGKKYTFTMRRAGMGDGTD NTFGSVIPATGPL PASGKMWIAGDG EAGKKYTFTMRRA EAGKKYHFLMKKM. It also relates to compositions and use of these peptides for treating and testing Porphyromonas gingialis.
    Type: Application
    Filed: March 22, 2005
    Publication date: August 4, 2005
    Applicants: The University of Melbourne, CSL Limited, Victorian Dairy Industry Association
    Inventors: Neil O'Brien-Simpson, Eric Reynolds