Patents by Inventor Nenad Maras

Nenad Maras has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for preparing dolutegravir and cabotegravir and analogues thereof
    Patent number: 10335394
    Abstract: The present invention relates to processes for preparing substances with antiviral activity, in particular the integrase inhibitors dolutegravir and cabotegravir and analogues thereof, as well as intermediates useful in the processes.
    Type: Grant
    Filed: January 15, 2016
    Date of Patent: July 2, 2019
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Nenad Maras, Lovro Selic, Anja Cusak
  • Processes for Preparing Dolutegravir and Cabotegravir and Analogues Thereof
    Publication number: 20170368040
    Abstract: The present invention relates to processes for preparing substances with antiviral activity, in particular the integrase inhibitors dolutegravir and cabotegravir and analogues thereof, as well as intermediates useful in the processes.
    Type: Application
    Filed: January 15, 2016
    Publication date: December 28, 2017
    Applicant: Lek Pharmaceuticals d.d.
    Inventors: Nenad Maras, Lovro Selic, Anja Cusak
  • Synthesis of Substituted 1H-Pyrazolo[3,4-D]Pyrimidines
    Publication number: 20170327504
    Abstract: The present invention refers to the synthesis and intermediates of substituted bicyclic compounds by using a central 1H-pyrazolo[3,4-d]pyrimidine of formula (I), which is assembled starting from 4,6-dichloropyrimidine carboxylic acid. The invention in particular refers to the synthesis of the Bruton's tyrosine kinase (Btk) inhibitor 1-((R)-3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one(ibrutinib) and its synthesis intermediates.
    Type: Application
    Filed: October 28, 2015
    Publication date: November 16, 2017
    Applicant: Sandoz AG
    Inventors: Christopher Rose, Herbert Silberger, Erwin Schreiner, Wolfgang Felzmann, Nenad Maras
  • Synthesis of triazolopyrimidine compounds
    Patent number: 9469614
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: October 18, 2016
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Borut Zupancic, Nenad Maras, Damjan Sterk
  • Synthesis of triazolopyrimidine compounds
    Patent number: 9278972
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.
    Type: Grant
    Filed: December 20, 2012
    Date of Patent: March 8, 2016
    Assignee: Lek Pharmaceuticals d.d.
    Inventors: Nenad Maras, Ivana Gazic Smilovic, Damjan Sterk
  • Synthesis of intermediates for preparing anacetrapib and derivatives thereof
    Patent number: 9212118
    Abstract: The present invention relates to the field of organic chemistry, more specifically to the synthesis of intermediate compounds which can be used in the synthesis of pharmaceutically active agents such as anacetrapib or derivatives thereof.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: December 15, 2015
    Assignee: LEK PHARMACEUTICALS D.D.
    Inventors: Jan Humljan, Nenad Maras
  • Synthesis of Triazolopyrimidine Compounds
    Publication number: 20140371449
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific intermediates suitable for the preparation of triazolopyrimidine compounds such as ticagrelor.
    Type: Application
    Filed: December 20, 2012
    Publication date: December 18, 2014
    Applicant: Lek Pharmaceuticals d.d.
    Inventors: Nenad Maras, Ivana Gazic Smilovic, Damjan Sterk
  • Synthesis of Triazolopyrimidine Compounds
    Publication number: 20140256747
    Abstract: The present invention relates to the field of organic synthesis and describes the synthesis of specific triazolopyrimidine compounds and intermediates thereof as well as related derivatives.
    Type: Application
    Filed: October 26, 2012
    Publication date: September 11, 2014
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Borut Zupancic, Nenad Maras, Damjan Sterk
  • SYNTHESIS OF INTERMEDIATES FOR PREPARING ANACETRAPIB AND DERIVATIVES THEREOF
    Publication number: 20140135368
    Abstract: The present invention relates to the field of organic chemistry, more specifically to the synthesis of intermediate compounds which can be used in the synthesis of pharmaceutically active agents such as anacetrapib or derivatives thereof.
    Type: Application
    Filed: December 21, 2011
    Publication date: May 15, 2014
    Applicant: LEK PHARMACEUTICALS D.D.
    Inventors: Jan Humljan, Nenad Maras