Patents by Inventor Nenad Milicevic

Nenad Milicevic has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11169061
    Abstract: A method and system for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid containing the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: November 9, 2021
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Claudio Cherubini, Martin Kopp, Nenad Milicevic, Daniel Mueller, Emad Sarofim, Goran Savatic
  • Patent number: 11112419
    Abstract: A laboratory distribution system is presented. The system comprises diagnostic laboratory container carriers and a conveyor. The conveyor comprises an endless drive defining a closed-loop conveyor pathway. The system comprises supporting elements attached to the endless drive. The supporting elements receive a container carrier and transport the container carrier in an upright position along a pathway section. The supporting elements are mounted pivotally about a horizontal pivot axis to the drive and structured such that a center of gravity of the supporting element with or without an empty or loaded container carrier is arranged below and vertically aligned with the pivot axis when the supporting element is in an upright position such that each supporting element is free to pivot about the associated pivot axis under the effect of gravitational forces acting on the supporting element for maintaining the supporting elements in an upright position while travelling along the path.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: September 7, 2021
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Hans van Mierlo, Gottlieb Schacher, Marcel Kaeppeli, Reto Huesser, Andreas Drechsler, Matthias Goetz, Nenad Milicevic
  • Publication number: 20200033240
    Abstract: A method and system for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
    Type: Application
    Filed: August 16, 2019
    Publication date: January 30, 2020
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Claudio Cherubini, Martin Kopp, Nenad Milicevic, Daniel Mueller, Emad Sarofim, Goran Savatic
  • Patent number: 10436685
    Abstract: A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion having a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion having a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion having a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: October 8, 2019
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Claudio Cherubini, Martin Kopp, Nenad Milicevic, Daniel Mueller, Emad Sarofim, Goran Savatic
  • Publication number: 20190004077
    Abstract: A laboratory distribution system is presented. The system comprises diagnostic laboratory container carriers and a conveyor. The conveyor comprises an endless drive defining a closed-loop conveyor pathway. The system comprises supporting elements attached to the endless drive. The supporting elements receive a container carrier and transport the container carrier in an upright position along a pathway section. The supporting elements are mounted pivotally about a horizontal pivot axis to the drive and structured such that a center of gravity of the supporting element with or without an empty or loaded container carrier is arranged below and vertically aligned with the pivot axis when the supporting element is in an upright position such that each supporting element is free to pivot about the associated pivot axis under the effect of gravitational forces acting on the supporting element for maintaining the supporting elements in an upright position while travelling along the path.
    Type: Application
    Filed: July 10, 2018
    Publication date: January 3, 2019
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Hans van Mierlo, Gottlieb Schacher, Marcel Kaeppeli, Reto Huesser, Andreas Dreschler, Matthias Goetz, Nenad Milicevic
  • Patent number: 9957111
    Abstract: A conveyor device for conveying test tube holders in a laboratory distribution system is presented. The conveyor device is a screw conveyor device comprising a helical track having a helix axis and a drive shaft having an axis of rotation parallel or coaxial to the helix axis, which drive shaft is adapted to be driven to rotate about the axis of rotation for causing a movement of one test tube holder or a plurality of test tube holders contacting the helical track between an entry region and an exit region. The entry region and the exit region are spaced in a direction of the helix axis. A laboratory distribution system for conveying test tube holders and a laboratory automation system comprising a laboratory distribution system are also presented.
    Type: Grant
    Filed: September 26, 2016
    Date of Patent: May 1, 2018
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Nenad Milicevic, Gottlieb Schacher
  • Publication number: 20180010990
    Abstract: A method for processing particles contained in a liquid biological sample is presented. The method uses a rotatable vessel for processing particles contained in a liquid biological sample. The rotatable vessel has a longitudinal axis about which the vessel is rotatable, an upper portion comprising a top opening for receiving the liquid comprising the particles, a lower portion for holding the liquid while the rotatable vessel is resting, the lower portion comprising a bottom, and an intermediate portion located between the upper portion and the lower portion, the intermediate portion comprising a lateral collection chamber for holding the liquid while the rotatable vessel is rotating. The method employs dedicated acceleration and deceleration profiles for sedimentation and re-suspension of the particles of interest.
    Type: Application
    Filed: January 27, 2017
    Publication date: January 11, 2018
    Inventors: Claudio Cherubini, Martin Kopp, Nenad Milicevic, Daniel Mueller, Emad Sarofim, Goran Savatic
  • Publication number: 20170101272
    Abstract: A conveyor device for conveying test tube holders in a laboratory distribution system is presented. The conveyor device is a screw conveyor device comprising a helical track having a helix axis and a drive shaft having an axis of rotation parallel or coaxial to the helix axis, which drive shaft is adapted to be driven to rotate about the axis of rotation for causing a movement of one test tube holder or a plurality of test tube holders contacting the helical track between an entry region and an exit region. The entry region and the exit region are spaced in a direction of the helix axis. A laboratory distribution system for conveying test tube holders and a laboratory automation system comprising a laboratory distribution system are also presented.
    Type: Application
    Filed: September 26, 2016
    Publication date: April 13, 2017
    Inventors: Claudio Cherubini, Andreas Drechsler, Reto Huesser, Nenad Milicevic, Gottlieb Schacher
  • Patent number: 8580567
    Abstract: A method for the automated analysis of liquid samples using at least one microfluidic structure is disclosed as well as microfluidic structures, a device having at least one of the microfluidic structures, a kit and a system including such microfluidic device. In one embodiment, the method may comprise: transferring a sample into a first fluid reservoir which is in fluid communication with a second fluid reservoir by a flow channel; spinning the microfluidic structure so as to transport the sample into one or more dead-end recesses or chambers; transferring a control fluid into the structure which generates a barrier to flow and diffusion of the sample contained in the one or more dead-end recesses or chambers; and analyzing the sample contained in the one or more dead-end recesses or chambers.
    Type: Grant
    Filed: October 13, 2010
    Date of Patent: November 12, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Emad Sarofim, Edwin Oosterbroek, Claudio Cherubini, Nenad Milicevic
  • Publication number: 20110250695
    Abstract: A method for the automated analysis of liquid samples using at least one microfluidic structure is disclosed as well as microfluidic structures, a device having at least one of the microfluidic structures, a kit and a system including such microfluidic device. In one embodiment, the method may comprise: transferring said sample into a first fluid reservoir which is in fluid communication with a second fluid reservoir by a flow channel; spinning said microfluidic structure so as to transport said sample into one or more dead-end recesses or chambers; transferring a control fluid into the structure which generates a barrier to flow and diffusion of said sample contained in said one or more dead-end recesses or chambers; and analyzing said sample contained in said one or more dead-end recesses or chambers.
    Type: Application
    Filed: October 13, 2010
    Publication date: October 13, 2011
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Emad Sarofim, Edwin Oosterbroek, Claudio Cherubini, Nenad Milicevic