Patents by Inventor Niccolo Terrando

Niccolo Terrando has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Systems and methods for percutaneous nerve stimulation
    Patent number: 11083892
    Abstract: The present disclosure provides systems and methods relating to neuromodulation. In particular, the present disclosure provides systems and methods for minimally invasive, targeted, vagus nerve stimulation (pVNS), and the efficacy of this approach with respect to microglial activation and the amelioration of cognitive dysfunction. The systems and methods of neuromodulation disclosed herein can be used to facilitate the treatment of various diseases associated with pathological neural activity.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: August 10, 2021
    Assignee: DUKE UNIVERSITY
    Inventors: Niccolo Terrando, William Huffman, Warren Grill
  • SYSTEMS AND METHODS FOR PERCUTANEOUS NERVE STIMULATION
    Publication number: 20190336770
    Abstract: The present disclosure provides systems and methods relating to neuromodulation. In particular, the present disclosure provides systems and methods for minimally invasive, targeted, vagus nerve stimulation (pVNS), and the efficacy of this approach with respect to microglial activation and the amelioration of cognitive dysfunction. The systems and methods of neuromodulation disclosed herein can be used to facilitate the treatment of various diseases associated with pathological neural activity.
    Type: Application
    Filed: May 1, 2019
    Publication date: November 7, 2019
    Inventors: Niccolo Terrando, William Huffman, Warren Grill
  • COMPOSITIONS AND METHODS FOR TREATING POST OPERATIVE COGNITIVE DYSFUNCTION AND NEUROINFLAMMATION WITH ANNEXIN A1 (ANXA1) PEPTIDES
    Publication number: 20180153952
    Abstract: The present disclosure provides compositions and methods for treating post-operative cognitive dysfunction with Annexin A1 (ANXA1) peptides.
    Type: Application
    Filed: December 1, 2017
    Publication date: June 7, 2018
    Inventors: Zhiquan Zhang, Niccolo Terrando, Qing Ma, Mihai V. Podgoreanu, Joseph P. Mathew, Mark F. Newman
  • METHODS
    Publication number: 20160333088
    Abstract: The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
    Type: Application
    Filed: March 8, 2016
    Publication date: November 17, 2016
    Inventors: Mervyn Maze, Marc Feldman, Niccolo Terrando, Mario Cibelli, Daqing Ma, Michael Fertleman
  • Method for treatment of post operative cognitive dysfunction
    Patent number: 9308254
    Abstract: The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: April 12, 2016
    Assignee: IMPERIAL INNOVATIONS LIMITED
    Inventors: Mervyn Maze, Marc Feldman, Niccolo Terrando, Mario Cibelli, Daqing Ma, Michael Fertleman
  • METHODS
    Publication number: 20130084299
    Abstract: The present invention provides method, uses and agents for preventing or reducing cognitive decline in a patient following a planned inflammatory trigger. Such planned inflammatory trigger can be a surgical procedure or chemotherapy. The invention further provides methods, uses and agents for reducing cognitive decline in a patient with a cognitive disorder, wherein said patient has been exposed to an inflammatory trigger. Pharmaceutical compositions and kits are also provided.
    Type: Application
    Filed: February 17, 2011
    Publication date: April 4, 2013
    Applicant: IMPERIAL INNOVATIONS LIMITED
    Inventors: Mervyn Maze, Marc Feldman, Niccolo Terrando, Mario Cibelli, Daqing Ma, Michael Fertleman