Patents by Inventor Nicholas George Hatsopoulos

Nicholas George Hatsopoulos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7392079
    Abstract: A system using neurological control signals to control a device is disclosed. The system may include a sensor sensing electrical activity of a plurality of neurons over time and a vector generator generating a neural control vector from the sensed electrical activity of the plurality of neurons over time. The system may also include a control filter to which the neural control vector is applied to provide a control variable and an output device controlled by the control variable.
    Type: Grant
    Filed: March 16, 2006
    Date of Patent: June 24, 2008
    Assignee: Brown University Research Foundation
    Inventors: John Philip Donoghue, Nicholas George Hatsopoulos, Mijail Demian Serruya, Matthew Richard Fellows, Liam Paninski
  • Patent number: 7212851
    Abstract: A brain implant system consistent with embodiments of the present invention includes an electrode array having a plurality of electrodes for sensing neuron signals. A method for manufacturing the electrode array includes machining a piece of an electrically conductive substance to create a plurality of electrodes extending from a base member. Each electrode also has a corresponding base section. A nonconductive layer is provided around at least a portion of the base section of each electrode to support the plurality of electrodes. The base section of the electrodes are then cut to separate the base member from the plurality of electrodes supported by the nonconductive support layer. The present invention also includes a complete brain implant system using the above electrode array.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: May 1, 2007
    Assignee: Brown University Research Foundation
    Inventors: John Philip Donoghue, Nicholas George Hatsopoulos, Sylvain Martel, Timothy A. Fofonoff, Robert J. Dyer, Ian W. Hunter
  • Publication number: 20040249302
    Abstract: System and methods consistent with the present invention decode brain signals. The system includes a receiver for receiving an input signal representing multiple individual neuron signals, and a frequency filter for separating the multiple neuron signals from the received input neural signal. A rectifier full wave rectifies the filtered neural signal and an integrator integrates the rectified neural signal to obtain an envelope of the rectified neural signal. As a result of this processing, sample values of the neural signal envelope represent neurological activity.
    Type: Application
    Filed: June 9, 2003
    Publication date: December 9, 2004
    Applicant: Cyberkinetics, Inc.
    Inventors: John P. Donoghue, Nicholas George Hatsopoulos, Mijail Serruya
  • Publication number: 20040082875
    Abstract: A brain implant system consistent with embodiments of the present invention includes an electrode array having a plurality of electrodes for sensing neuron signals. A method for manufacturing the electrode array includes machining a piece of an electrically conductive substance to create a plurality of electrodes extending from a base member. Each electrode also has a corresponding base section. A nonconductive layer is provided around at least a portion of the base section of each electrode to support the plurality of electrodes. The base section of the electrodes are then cut to separate the base member from the plurality of electrodes supported by the nonconductive support layer. The present invention also includes a complete brain implant system using the above electrode array.
    Type: Application
    Filed: October 24, 2002
    Publication date: April 29, 2004
    Applicants: Brown University Research Foundation, Massachusetts Institute of Technology
    Inventors: John Philip Donoghue, Nicholas George Hatsopoulos, Sylvain Martel, Timothy A. Fofonoff, Robert J. Dyer, Ian W. Hunter
  • Publication number: 20030105409
    Abstract: A continuous tracking task and multielectrode recording was used to describe position and velocity information encoding and decoding in primate motor cortex during visually guided hand motion. The pursuit tracking task (PTT) controls hand motion to remove statistical dependencies among kinematics and neural activity, provides reasonable data stationarity, and a broad sample of velocity and position space allowing description of the time varying features of MI tuning for hand motion. MI has a continuous contribution to visually guided hand motion. The amount of information for each cell was low and restricted to the slow components of movement. Decoding using a linear regression method confirms that position and velocity information can be recovered from the firing of ensembles of MI neurons and demonstrates that MI firing contains sufficient information to predict any future hand trajectory with moderate accuracy based on the firing patterns of small numbers of regionally associated MI neuron populations.
    Type: Application
    Filed: November 14, 2001
    Publication date: June 5, 2003
    Inventors: John Philip Donoghue, Nicholas George Hatsopoulos, Mijail Demian Serruya, Matthew Richard Fellows, Liam Paninski