Patents by Inventor Nicholas Noinaj

Nicholas Noinaj has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8632989
    Abstract: In one aspect, the present invention provides an isolated mutant insulin degrading enzyme (IDE) having an amino acid sequence that is at least 90% identical to SEQ ID NO:1 over its entire length and comprises at least one amino acid substitution at any of amino acid residues 332, 339, 341, 359, 360, 361, 374, 429, 609, 898, 899 or 901 of the sequence. The mutant IDE has a differential activity relative to that of wild-type IDE. Also provided is a polynucleotide encoding the polypeptide of the invention.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: January 21, 2014
    Assignee: University of Kentucky Research Foundation
    Inventors: David W. Rodgers, Louis B. Hersh, Nicholas Noinaj, Eun Suk Song