Patents by Inventor Nicholas Ronald Wurtz

Nicholas Ronald Wurtz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10316035
    Abstract: The present invention provides compounds of Formula (I): wherein A, Y and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
    Type: Grant
    Filed: August 30, 2016
    Date of Patent: June 11, 2019
    Assignee: Bristol-Myers Squibb Company
    Inventors: Andrew Quoc Viet, Nicholas Ronald Wurtz, Scott A. Shaw, Ellen K. Kick, Andrew K. Dilger, Kumar Balashanmuga Pabbisetty
  • Publication number: 20180244671
    Abstract: The present invention provides compounds of Formula (I): wherein A, Y and R1 are each as defined in the specification, and compositions comprising any of such novel compounds. These compounds are myeloperoxidase (MPO) inhibitors and/or eosinophil peroxidase (EPX) inhibitors, which may be used as medicaments.
    Type: Application
    Filed: August 30, 2016
    Publication date: August 30, 2018
    Applicant: Bristol-Meyers Squibb Company
    Inventors: Andrew Quoc Viet, Nicholas Ronald Wurtz, Scott A. Shaw, Ellen K. Kick, Andrew K. Dilger, Kumar Balashanmuga Pabbisetty
  • Patent number: 9174974
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.
    Type: Grant
    Filed: June 5, 2013
    Date of Patent: November 3, 2015
    Assignee: Bristol-Myers Squibb Company
    Inventors: Xiaojun Zhang, Peter Glunz, Eldon Scott Priestley, James A. Johnson, Nicholas Ronald Wurtz, Vladimir Ladziata
  • Publication number: 20150148313
    Abstract: The present invention provides compounds of Formula (I): as defined in the specification and compositions comprising any of such novel compounds. These compounds are Factor VIIa inhibitors which may be used as medicaments.
    Type: Application
    Filed: June 5, 2013
    Publication date: May 28, 2015
    Inventors: Xiaojun Zhang, Peter Glunz, Eldon Scott Priestley, James A. Johnson, Nicholas Ronald Wurtz, Vladimir Ladziata
  • Patent number: 8420830
    Abstract: The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, C, D, L, M, W, Z1, Z2, Z3, Z4, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: December 19, 2007
    Date of Patent: April 16, 2013
    Assignee: Bristol-Myers Squibb Company
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Peter W. Glunz, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata, Luciano Mueller
  • Patent number: 8039506
    Abstract: The present invention provides novel bicyclic lactams derivatives, and analogues thereof, of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, B, C, W, Y, Z1, Z2, Z3, Z4, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: December 17, 2007
    Date of Patent: October 18, 2011
    Assignee: Bristol-Myers Squibb Company
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata
  • Publication number: 20100113488
    Abstract: The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, C, D, L, M, W, Z1, Z2, Z3, Z4, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Application
    Filed: December 19, 2007
    Publication date: May 6, 2010
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Peter W. Glunz, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata, Luciano Mueller
  • Publication number: 20100041664
    Abstract: The present invention provides novel bicyclic lactams derivatives, and analogues thereof, of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein the variables A, B, C, W, Y, Z1, Z2, Z3, Z4, R8, and R9 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
    Type: Application
    Filed: December 17, 2007
    Publication date: February 18, 2010
    Inventors: Nicholas Ronald Wurtz, Eldon Scott Priestley, Daniel L. Cheney, Xiaojun Zhang, Brandon Parkhurst, Vladimir Ladziata
  • Patent number: 7592331
    Abstract: The present invention relates generally to novel macrocycles of Formula (I): or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, L, M, W, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of the serine protease coagulation factor VIIa which can be used as medicaments.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: September 22, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Eldon Scott Priestley, Daniel L. Cheney, Nicholas Ronald Wurtz, Peter W. Glunz