Patents by Inventor Nicholas S. Bodor

Nicholas S. Bodor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190328707
    Abstract: A method of treating hyperhidrosis in a mammalian subject, said method comprising topically administering a composition comprising a compound having the formula (I): wherein R is methyl or ethyl, said compound having the R stereoisomeric configuration at the 2 position and the R, S, or RS stereoisomeric configuration at the 1? and 3? position, or being a mixture thereof; in an amount of from about 1.0% to about 25% of said compound, an additional active substance that is an antiperspirant active substance and, optionally, a pharmaceutically acceptable vehicle, to skin of an area of a mammalian subject suffering from hyperhidrosis in a one to four times daily dosing regimen.
    Type: Application
    Filed: July 2, 2019
    Publication date: October 31, 2019
    Inventors: NICHOLAS S. BODOR, DAVID ANGULO
  • Patent number: 10383846
    Abstract: The subject application is directed to a method of treating hyperhidrosis in a mammalian subject comprising topically administering a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound selected from the group consisting of: (i) 3-(2-cyclopentyl-2-phenyl-2-hydroxyacetoxy)-1-(methoxycarbonylmethyl)-1-methylpyrrolidinium bromide; and (ii) 3-(2-cyclopentyl-2-phenyl-2-hydroxyacetoxy)-1-(ethoxycarbonylmethyl)-1-methylpyrrolidinium bromide; to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours; and such that sweat production is reduced by an amount substantially equivalent to an amount that sweat production is reduced as compared to untreated, baseline conditions, following administration of a composition comprising the same concentration of glycopyrrolate.
    Type: Grant
    Filed: February 16, 2018
    Date of Patent: August 20, 2019
    Assignee: BODOR LABORATORIES, INC.
    Inventors: Nicholas S. Bodor, David Angulo
  • Publication number: 20190247362
    Abstract: Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.
    Type: Application
    Filed: July 20, 2017
    Publication date: August 15, 2019
    Inventors: Nicholas S. BODOR, John J. KOLENG, David ANGULO
  • Publication number: 20190224164
    Abstract: Methods and compositions for treating chronic obstructive pulmonary disease (COPD) and other obstructive diseases of the respiratory tract by administering soft anticholinergic esters once or twice daily with fewer systemic side-effects than glycopyrrolate.
    Type: Application
    Filed: June 30, 2017
    Publication date: July 25, 2019
    Inventor: Nicholas S. BODOR
  • Patent number: 10335367
    Abstract: Selected anticholinergic zwittehons are administered to slow the progression of myopia in children and to treat myopia generally.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: July 2, 2019
    Assignee: BODOR LABORATORIES, INC.
    Inventor: Nicholas S. Bodor
  • Publication number: 20180250265
    Abstract: Intra-oral formulations comprising soft anticholinergic alkyl esters are useful for treating excessive drooling conditions in subjects, such as humans, suffering from sialorrhea. Preferably, at least one soft anticholinergic ester is provided in an effective amount or concentration in an anhydrous intra-oral formulation that can inhibit excessive drooling resulting from a condition known as sialorrhea.
    Type: Application
    Filed: September 6, 2016
    Publication date: September 6, 2018
    Inventor: Nicholas S. BODOR
  • Publication number: 20180243209
    Abstract: Selected anticholinergic zwittehons are administered to slow the progression of myopia in children and to treat myopia generally.
    Type: Application
    Filed: August 26, 2016
    Publication date: August 30, 2018
    Inventor: Nicholas S. BODOR
  • Publication number: 20180235869
    Abstract: Intra-oral formulations comprising soft anticholinergic zwitterions are useful for treating excessive drooling conditions in subjects, such as humans, suffering from sialorrhea. Preferably, at least one soft anticholinergic zwitterion is provided in an effective amount or concentration in an intra-oral formulation that inhibits excessive drooling resulting from a condition known as sialorrhea.
    Type: Application
    Filed: September 6, 2016
    Publication date: August 23, 2018
    Inventor: Nicholas S. BODOR
  • Publication number: 20180228770
    Abstract: Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.
    Type: Application
    Filed: July 21, 2016
    Publication date: August 16, 2018
    Inventors: Nicholas S. BODOR, John J. KOLENG, David ANGULO
  • Publication number: 20180185331
    Abstract: The subject application is directed to a method of treating hyperhidrosis in a mammalian subject comprising topically administering a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound selected from the group consisting of: (i) 3-(2-cyclopentyl-2-phenyl-2-hydroxyacetoxy)-1-(methoxycarbonylmethyl)-1-methylpyrrolidinium bromide; and (ii) 3-(2-cyclopentyl-2-phenyl-2-hydroxyacetoxy)-1-(ethoxycarbonylmethyl)-1-methylpyrrolidinium bromide; to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours; and such that sweat production is reduced by an amount substantially equivalent to an amount that sweat production is reduced as compared to untreated, baseline conditions, following administration of a composition comprising the same concentration of glycopyrrolate.
    Type: Application
    Filed: February 16, 2018
    Publication date: July 5, 2018
    Inventors: Nicholas S. Bodor, David Angulo
  • Patent number: 9895350
    Abstract: A method of treating hyperhidrosis in a mammalian subject including: a) providing a composition including a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Grant
    Filed: July 1, 2016
    Date of Patent: February 20, 2018
    Assignee: BODOR LABORATORIES, INC.
    Inventors: Nicholas S. Bodor, David Angulo
  • Publication number: 20180021300
    Abstract: Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.
    Type: Application
    Filed: July 21, 2017
    Publication date: January 25, 2018
    Inventors: Nicholas S. BODOR, John J. KOLENG, David ANGULO
  • Publication number: 20170020845
    Abstract: Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.
    Type: Application
    Filed: March 12, 2015
    Publication date: January 26, 2017
    Applicant: Bodor Laboratories, Inc.
    Inventors: NICHOLAS S. BODOR, JOHN J. KOLENG, DAVID ANGULO
  • Patent number: 9492429
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: November 15, 2016
    Assignee: BODOR LABORATORIES, INC.
    Inventors: Nicholas S. Bodor, David Angulo
  • Publication number: 20160310464
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Application
    Filed: July 1, 2016
    Publication date: October 27, 2016
    Inventors: NICHOLAS S. BODOR, DAVID ANGULO
  • Publication number: 20160067214
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Application
    Filed: November 13, 2015
    Publication date: March 10, 2016
    Inventors: NICHOLAS S. BODOR, DAVID ANGULO
  • Publication number: 20150374621
    Abstract: Selected anticholinergic zwitterions are administered to slow the progression of myopia in children and to treat myopia generally.
    Type: Application
    Filed: September 4, 2015
    Publication date: December 31, 2015
    Inventor: Nicholas S. BODOR
  • Patent number: 9220707
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: December 29, 2015
    Assignee: BODOR LABORATORIES, INC.
    Inventors: Nicholas S. Bodor, David Angulo
  • Publication number: 20150320722
    Abstract: Topical formulations comprising soft glycopyrrolates are useful for treating excessive sweating conditions in subjects, such as humans suffering from hyperhidrosis. Preferably, at least one soft anticholinergic agent is provided in an effective amount or concentration in an anhydrous formulation that can inhibit excessive perspiration resulting from a condition such as hyperhidrosis.
    Type: Application
    Filed: July 21, 2015
    Publication date: November 12, 2015
    Inventors: Nicholas S. BODOR, John J. Koleng, David Angulo
  • Publication number: 20140275204
    Abstract: A method of treating hyperhidrosis in a mammalian subject comprising: a) providing a composition comprising a pharmaceutically acceptable vehicle and from about 1.0% to about 25% of a compound having the formula: and b) topically administering the composition to skin of an area of a mammalian subject suffering from hyperhidosis, before bedtime, such that, compared to untreated, baseline conditions, sweat production is reduced by at least about 25% for at least about six (6) hours.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 18, 2014
    Applicant: BODOR LABORATORIES, INC.
    Inventors: NICHOLAS S. BODOR, DAVID ANGULO