Patents by Inventor Nicole Dusch

Nicole Dusch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processes for preparing D-pantothenic acid using coryneform bacteria
    Publication number: 20020068335
    Abstract: The present invention provides processes for preparing D-pantothenic acid using Coryneform bacteria having an enhanced pfkA gene.
    Type: Application
    Filed: June 25, 2001
    Publication date: June 6, 2002
    Applicant: DEGUSSA AG
    Inventors: Georg Thierbach, Nicole Dusch
  • Process for the fermentative preparation of D-pantothenic acid using coryneform bacteria
    Publication number: 20020042104
    Abstract: The invention provides a process for preparing D-pantothenic acid by the fermentation of coryneform bacteria in which bacteria are used in which the nucleotide sequence (pck gene) coding for phosphoenolpyruvate carboxykinase (EC 4.1.1.
    Type: Application
    Filed: May 10, 2001
    Publication date: April 11, 2002
    Inventors: Nicole Dusch, Georg Thierbach
  • Method for the fermentative production of D-pantothenic acid by enhancement of the panD gene in microorganisms
    Patent number: 6184007
    Abstract: The invention is a method for the production of D-pantothenic acid by the fermentation of microorganisms in which at least the panD gene is enhanced (overexpressed), optionally in combination with the panB and/or panC gene, to provide for the enrichment of the pantothenic acid in the medium or the cells of the microorganisms.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: February 6, 2001
    Assignee: Degussa-Huls Aktiengesellschaft
    Inventors: Nicole Dusch, Jörn Kalinowski, Alfred Puhler
  • Method for the fermentative production of D-pantothenic acid using strains of the family enterobacteriaceae
    Patent number: 6184006
    Abstract: A method for the production of D-pantothenic acid by the fermentation of microorganisms of the family Enterobacteriacae producing D-pantothenic acid which is characterized in that strains are used which a) Contain the plasmid pFV31 and/or pFV202 and that b) A panD gene and optionally other nucleotide sequences coding for aspartate-1-decarboxylase are enhanced, especially overexpressed in these microorganisms, c) The pantothenic acid is enriched in the medium or in the cells of the microorganisms and d) The pantothenic acid formed is isolated.
    Type: Grant
    Filed: May 26, 1999
    Date of Patent: February 6, 2001
    Assignee: Degussa-Hüls Aktiengesellschaft
    Inventors: Mechthild Rieping, Georg Thierbach, Walter Pfefferle, Nicole Dusch, Jorn Kalinowski, Alfred Puhler
  • Mutant E. coli kiz strains for production of pantothenic acid
    Patent number: 6171845
    Abstract: The invention relates to a process for the preparation and improvement of D-pantothenic acid-producing microorganisms by amplification of nucleotide sequences which code for ketopantoate reductase, in particular the panE gene, individually or in combination with one another, and optionally additionally of the ilvC gene, the microorganisms containing these nucleotide sequences, and a process for the preparation of D-pantothenic acid comprising fermentation of these microorganisms, concentration of pantothenic acid in the medium or in the cells of the microorganisms, and isolation of the D-pantothenic acid.
    Type: Grant
    Filed: October 12, 1999
    Date of Patent: January 9, 2001
    Assignee: Degussa-Huls AG
    Inventors: Frank Elischweski, Jorn Kalinowski, Alfred Puhler, Nicole Dusch, Jurgen Dohmen, Mike Farwick, Georg Thierbach