Patents by Inventor Nicole K. PAULK

Nicole K. PAULK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10385320
    Abstract: The present invention relates to variant AAV capsid polypeptides, wherein the variant AAV capsid polypeptides exhibit increased transduction and/or tropism in human muscle tissue or cells as compared non-variant parent capsid polypeptides.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: August 20, 2019
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Mark A. Kay, Nicole K. Paulk
  • Patent number: 10179176
    Abstract: The present invention relates to variant AAV capsid polypeptides, wherein the variant capsid polypeptides exhibit an enhanced neutralization profile, increased transduction and/or tropism in human liver tissue or hepatocyte cells (i.e., human hepatocyte cells), or both, as compared non-variant parent capsid polypeptides.
    Type: Grant
    Filed: February 16, 2017
    Date of Patent: January 15, 2019
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Mark A. Kay, Nicole K. Paulk
  • Publication number: 20170360962
    Abstract: The present invention relates to variant AAV capsid polypeptides, wherein the variant capsid polypeptides exhibit an enhanced neutralization profile, increased transduction and/or tropism in human liver tissue or hepatocyte cells (i.e., human hepatocyte cells), or both, as compared non-variant parent capsid polypeptides.
    Type: Application
    Filed: August 18, 2017
    Publication date: December 21, 2017
    Inventors: Mark A. Kay, Nicole K. Paulk
  • Publication number: 20170348433
    Abstract: The present invention relates to variant AAV capsid polypeptides, wherein the variant capsid polypeptides exhibit an enhanced neutralization profile, increased transduction and/or tropism in human liver tissue or hepatocyte cells (i.e., human hepatocyte cells), or both, as compared non-variant parent capsid polypeptides.
    Type: Application
    Filed: February 16, 2017
    Publication date: December 7, 2017
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Mark A. KAY, Nicole K. PAULK
  • Publication number: 20170159026
    Abstract: The present invention relates to variant AAV capsid polypeptides, wherein the variant AAV capsid polypeptides exhibit increased transduction and/or tropism in human muscle tissue or cells as compared non-variant parent capsid polypeptides.
    Type: Application
    Filed: December 2, 2016
    Publication date: June 8, 2017
    Inventors: Mark A. KAY, Nicole K. PAULK