Patents by Inventor Nikolai Aljuri

Nikolai Aljuri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11931170
    Abstract: Lung conditions are diagnosed and optionally treated using a functional assessment catheter or a functional lung assessment and treatment catheter. A flow restrictive component is initially placed in a bronchus or lung passageway upstream from a diseased lung region. The isolated lung region is then functionally assessed through the catheter, while the flow restrictive component remains in place. If the patient is a good candidate for treatment by occlusive or restrictive treatment techniques, the flow resistive component may be left in place. If the patient is not suitable for such treatment, the flow resistive component may be removed.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: March 19, 2024
    Assignee: Pulmonx Corporation
    Inventors: Ajit Nair, Son Gia, Roger Farhnoltz, Nikolai Aljuri
  • Patent number: 11903606
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: February 20, 2024
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Edward Karpman, Chris Danek
  • Publication number: 20240032958
    Abstract: A system to treat a patient comprises a user interface that allows a physician to view an image of tissue to be treated in order to develop a treatment plan to resect tissue with a predefined removal profile. The image may comprise a plurality of images, and the planned treatment is shown on the images. The treatment probe may comprise an anchor, and the image shown on the screen may have a reference image marker shown on the screen corresponding to the anchor. The planned tissue removal profile can be displayed and scaled to the image of the target tissue of an organ such as the prostate, and the physician can adjust the treatment profile based on the scaled images to provide a treatment profile in three dimensions. The images shown on the display may comprise segmented images of the patient with treatment plan overlaid on the images.
    Type: Application
    Filed: August 23, 2023
    Publication date: February 1, 2024
    Applicant: PROCEPT BioRobotics Corporation
    Inventors: Nikolai ALJURI, Surag MANTRI, Luis BAEZ, George SURJAN, Michael W. SASNETT, Jonathan FOOTE
  • Patent number: 11883029
    Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.
    Type: Grant
    Filed: July 19, 2022
    Date of Patent: January 30, 2024
    Assignee: Pulmonx Corporation
    Inventors: Nikolai Aljuri, Rodney C. Perkins, Niyazi Beyhan
  • Patent number: 11871933
    Abstract: Disclosed herein are improved methods and apparatuses for providing hemostasis within a cavity defined by an internal surface of a bleeding tissue space. A catheter comprising a proximal end and a distal end may be advanced into the cavity through a proximal opening of the tissue space into the cavity. A distal balloon coupled to the catheter may be expanded, and the catheter tensioned to apply pressure to the internal surface of the tissue space to inhibit bleeding of the tissue space.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: January 16, 2024
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Surag Mantri, Nikolai Aljuri, Kevin Patrick Staid, James Luis Badia, Peter Bentley, Nishey Wanchoo
  • Patent number: 11857287
    Abstract: A surgical drape is configured for covering a patient and an ultrasonography probe during surgical treatment of the patient. The surgical drape may include a first portion that includes a canopy portion. The canopy portion can be sized and shaped to at least partially cover a mechanical arm coupled to the ultrasonography probe and a proximal portion of the ultrasonography probe, and the canopy portion can be configured to move with the proximal portion of the ultrasonography probe when the ultrasonography probe is supported by the mechanical arm. A second portion can be coupled to the first portion, in which the second portion is sized and shaped to cover at least a portion of a torso of the patient.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: January 2, 2024
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Surag Mantri, Matt Sprinkel, James Badia, Nishey Wanchoo, Mark Baerenrodt, Kevin Staid
  • Publication number: 20230338087
    Abstract: Methods and systems for modifying tissue use a pressurized fluid stream carrying coherent light energy. The methods and systems may be used for resecting and debulking soft and hard biological tissues. The coherent light is focused within a stream of fluid to deliver energy to the tissue to be treated.
    Type: Application
    Filed: June 30, 2023
    Publication date: October 26, 2023
    Applicant: AquaBeam, LLC
    Inventors: Nikolai ALJURI, Rodney C. PERKINS
  • Patent number: 11759258
    Abstract: Methods and systems for modifying tissue use a pressurized fluid stream carrying coherent light energy. The methods and systems may be used for resecting and debulking soft and hard biological tissues. The coherent light is focused within a stream of fluid to deliver energy to the tissue to be treated.
    Type: Grant
    Filed: April 30, 2021
    Date of Patent: September 19, 2023
    Assignee: AQUABEAM, LLC
    Inventors: Nikolai Aljuri, Rodney C. Perkins
  • Patent number: 11737776
    Abstract: A system to treat a patient comprises a user interface that allows a physician to view an image of tissue to be treated in order to develop a treatment plan to resect tissue with a predefined removal profile. The image may comprise a plurality of images, and the planned treatment is shown on the images. The treatment probe may comprise an anchor, and the image shown on the screen may have a reference image marker shown on the screen corresponding to the anchor. The planned tissue removal profile can be displayed and scaled to the image of the target tissue of an organ such as the prostate, and the physician can adjust the treatment profile based on the scaled images to provide a treatment profile in three dimensions. The images shown on the display may comprise segmented images of the patient with treatment plan overlaid on the images.
    Type: Grant
    Filed: April 10, 2020
    Date of Patent: August 29, 2023
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Surag Mantri, Luis Baez, George Surjan, Michael W. Sasnett, Jonathan Foote
  • Publication number: 20230063051
    Abstract: Prostate treatment using fluid stream to resect prostate tissue, thereby relieving symptoms of conditions such as BPH, prostatitis, and prostatic carcinoma. A device having a fluid delivery element is positioned within a lumen of the urethra within the prostate. A fluid stream is directed outwardly from the fluid delivery element toward a wall of the urethral lumen. The fluid delivery element is moved to scan the fluid stream over the wall to remove a volume of tissue surrounding the lumen. The fluid may be combined with therapeutically active substances or with substances that increase resection efficiency. Fluid force may be adjusted to provide selective tissue resection such that soft tissue is removed while harder tissue is left undamaged. In order to gain a working space within the urethra, another fluid may be introduced to insufflate the urethra in the region of treatment.
    Type: Application
    Filed: October 20, 2022
    Publication date: March 2, 2023
    Applicant: AquaBeam, LLC
    Inventors: Nikolai ALJURI, Rodney C. PERKINS
  • Patent number: 11553924
    Abstract: Disclosed herein are improved methods and apparatuses for providing hemostasis within a cavity defined by an internal surface of a bleeding tissue space. A catheter comprising a proximal end and a distal end may be advanced into the cavity through a proximal opening of the tissue space into the cavity. A distal balloon coupled to the catheter may be positioned adjacent a distal opening of the tissue space, and expanded to seal the distal opening. A hemostatic agent may be applied from the catheter to the internal surface of the tissue space to inhibit bleeding of the tissue space. The hemostatic agent may be applied without occluding the proximal opening, the distal opening, and a path extending therebetween with the hemostatic agent.
    Type: Grant
    Filed: April 5, 2019
    Date of Patent: January 17, 2023
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Surag Mantri, Nikolai Aljuri, Kevin Patrick Staid, James Luis Badia, Peter Bentley, Nishey Wanchoo
  • Publication number: 20230000497
    Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.
    Type: Application
    Filed: July 19, 2022
    Publication date: January 5, 2023
    Applicant: Pulmonx Corporation
    Inventors: Nikolai Aljuri, Rodney C. Perkins, Niyazi Beyhan
  • Patent number: 11478269
    Abstract: Prostate treatment using fluid stream to resect prostate tissue, thereby relieving symptoms of conditions such as BPH, prostatitis, and prostatic carcinoma. A device having a fluid delivery element is positioned within a lumen of the urethra within the prostate. A fluid stream is directed outwardly from the fluid delivery element toward a wall of the urethral lumen. The fluid delivery element is moved to scan the fluid stream over the wall to remove a volume of tissue surrounding the lumen. The fluid may be combined with therapeutically active substances or with substances that increase resection efficiency. Fluid force may be adjusted to provide selective tissue resection such that soft tissue is removed while harder tissue is left undamaged. In order to gain a working space within the urethra, another fluid may be introduced to insufflate the urethra in the region of treatment.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: October 25, 2022
    Assignee: AquaBeam, LLC
    Inventor: Nikolai Aljuri
  • Patent number: 11464536
    Abstract: A system to treat a patient comprises a user interface that allows a physician to view an image of tissue to be treated in order to develop a treatment plan to resect tissue with a predefined removal profile. The image may comprise a plurality of images, and the planned treatment is shown on the images. The treatment probe may comprise an anchor, and the image shown on the screen may have a reference image marker shown on the screen corresponding to the anchor. The planned tissue removal profile can be displayed and scaled to the image of the target tissue of an organ such as the prostate, and the physician can adjust the treatment profile based on the scaled images to provide a treatment profile in three dimensions. The images shown on the display may comprise segmented images of the patient with treatment plan overlaid on the images.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: October 11, 2022
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Surag Mantri, George Surjan, Michael W. Sasnett, Jonathan Foote
  • Publication number: 20220257274
    Abstract: An apparatus is configured to provide hemostasis with tissue removal in order to inhibit one or more of blood loss or tissue drainage. In many embodiments, a nozzle releases a liquid jet in a liquid medium in order to provide cavitation and a plurality of shedding pulses. The liquid jet, its cavitation and the plurality of shedding pulses can affect vascular tissue in order to promote clotting in order to inhibit bleeding. In many embodiments, vessels of the vascular tissue are affected at a distance from a region where cavitation of the water jet contacts the tissue. In many embodiments, the cavitation and plurality of shedding pules are related to a pulsatile shear wave propagating along the blood vessel that is related to clot promoting changes of the blood vessel.
    Type: Application
    Filed: April 29, 2022
    Publication date: August 18, 2022
    Applicant: PROCEPT BioRobotics Corporation
    Inventors: Nikolai ALJURI, Edward KARPMAN, Chris DANEK
  • Patent number: 11413045
    Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment.
    Type: Grant
    Filed: July 15, 2020
    Date of Patent: August 16, 2022
    Assignee: Pulmonx Corporation
    Inventors: Nikolai Aljuri, Rodney C. Perkins, Niyazi Beyhan
  • Patent number: 11406453
    Abstract: A surgical treatment apparatus comprises an elongate support, an elongate tube, and a movable endoscope having a stiff distal portion, in which the stiff distal portion of the endoscope is configured to move one or more components of the apparatus when the support remains substantially fixed. The support may comprise a plurality of spaced apart aspiration openings near the distal end in order to facilitate alignment with the treatment site. In many embodiments, an image guided treatment apparatus is configured for use with an imaging device. In many embodiments, a target resection profile is provided. The target resection profile and one or more tissue structures are displayed on an image, and the target resection profile displayed on the image is adjusted with user input.
    Type: Grant
    Filed: March 1, 2017
    Date of Patent: August 9, 2022
    Assignee: PROCEPT BioRobotics Corporation
    Inventors: Nikolai Aljuri, Surag Mantri, Peter Bentley, Luis Baez, James Luis Badia
  • Publication number: 20220240968
    Abstract: Embodiments of the present invention provide improved methods and apparatus of treating the prostate. In many embodiments, at least a portion of the prostate is enucleated with a water jet, in order to decrease the invasiveness of the surgery. The access to the prostate can be provided with one or more of open surgical access, percutaneous access, or urethral access. The prostate can be enucleated such that an inner portion of the prostate comprising adenomatous tissue of the prostate is separated from a portion an outer the prostate comprising the capsule. In many embodiments, the patient is treated with energy of the water jet configured to separate the capsule from the inner tissue of the prostate and to inhibit cutting of blood vessels.
    Type: Application
    Filed: April 21, 2022
    Publication date: August 4, 2022
    Applicant: PROCEPT BioRobotics Corporation
    Inventors: Nikolai ALJURI, Surag MANTRI
  • Publication number: 20220202467
    Abstract: Medical methods and systems are provided for effecting lung volume reduction by selectively ablating segments of lung tissue.
    Type: Application
    Filed: March 16, 2022
    Publication date: June 30, 2022
    Applicant: Pulmonx Corporation
    Inventors: Peter P. Soltesz, Nikolai Aljuri, Ajit Nair
  • Publication number: 20220184332
    Abstract: The volume of a hyperinflated lung compartment is reduced by sealing a distal end of the catheter in an airway feeding the lung compartment. Air passes out of the lung compartment through a passage in the catheter while the patient exhales. A one-way flow element associated with the catheter prevents air from re-entering the lung compartment as the patient inhales. Over time, the pressure of regions surrounding the lung compartment cause it to collapse as the volume of air diminishes. Residual volume reduction effectively results in functional lung volume expansion. Optionally, the lung compartment may be sealed in order to permanently prevent air from re-entering the lung compartment. The invention further discloses a catheter with a transparent occlusion element at its tip that enables examination of the lung passageway through a viewing scope.
    Type: Application
    Filed: March 7, 2022
    Publication date: June 16, 2022
    Applicant: Pulmonx Corporation
    Inventors: Nikolai Aljuri, Rodney C. Perkins, Ryan Olivera, Hoang Nguyen, Srikanth Radhakrishnan, Niyazi Beyhan