Patents by Inventor Nikolai D. Makarov

Nikolai D. Makarov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4476225
    Abstract: An apparatus for continuously disintegrating cells of microorganisms comprising a mixing vessel and an accumulating vessel communicating with one another through a disintegration device. The disintegration device comprises a hollow body having a seat in which there is installed a needle valve member. The hollow body further comprises a sleeve having a bottom wall incorporating the needle valve member and a side wall having openings for communicating the interior of the sleeve with the accumulating vessel. An insert is installed in the opened end of the sleeve which is connected to the sleeve and has a central passage coaxial with the valve member and communicating with the mixing vessel.
    Type: Grant
    Filed: July 12, 1982
    Date of Patent: October 9, 1984
    Assignee: Vsesojuzny Nauchnoissledovatelsky Institut Sinteza Belkov
    Inventors: Alfred N. Grigorian, Andrei P. Kovalev, Vitaly V. Lalov, Nikolai D. Makarov, Rady V. Katrush