Patents by Inventor Nina M. Graves

Nina M. Graves has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7881798
    Abstract: A medical device, such as an implantable medical device (IMD), determines values for one or more metrics that indicate the quality of a patient's sleep, and controls delivery of a therapy based on the sleep quality metric values. For example, the medical device may compare a sleep quality metric value with one or more threshold values, and adjust the therapy based on the comparison. In some embodiments, the medical device adjusts the intensity of therapy based on the comparison, e.g., increases the therapy intensity when the comparison indicates that the patient's sleep quality is poor. In some embodiments, the medical device automatically selects one of a plurality of therapy parameter set available for use in delivering therapy based on a comparison sleep quality metric values associated with respective therapy parameter sets within the plurality of available therapy parameter sets.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: February 1, 2011
    Assignee: Medtronic Inc.
    Inventors: Keith A. Miesel, Kenneth T. Heruth, Jonathan C. Werder, Steve R. LaPorte, Nina M. Graves
  • Patent number: 7865244
    Abstract: A medical device system includes a brain monitoring element, cardiopulmonary monitoring element, therapy module and a processor. The processor is configured to activate the therapy module upon detection of a cardiopulmonary event in the cardiopulmonary signal. The processor is further configured to monitor the brain signal and communicate to the therapy module to change the cardiopulmonary triggered therapeutic output to the brain based upon the brain monitoring. Methods of treating a person with a neurological disorder are also provided.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: January 4, 2011
    Assignee: Medtronic, Inc.
    Inventors: Jonathon E. Giftakis, Nina M. Graves
  • Patent number: 7787944
    Abstract: A medical device system includes a brain monitoring element, cardiac monitoring element, therapy module and a processor. The processor is configured to activate the therapy module upon detection of a cardiac event in the cardiac signal. The processor is further configured to monitor the brain signal and communicate to the therapy module to change the cardiac triggered therapeutic output to the brain based upon the brain monitoring. A method of treating a person with a neurological disorder is also provided.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: August 31, 2010
    Assignee: Medtronic, Inc.
    Inventors: Jonathon E. Giftakis, Nina M. Graves
  • Publication number: 20100121213
    Abstract: Intracranial pressure of a patient may be monitored in order to evaluate a seizure disorder. In some examples, trends in the intracranial pressure over time may be monitored, e.g., to detect changes to the patient's condition. In addition, in some examples, a seizure metric may be generated for a detected seizure based on sensed intracranial pressures. The seizure metric may indicate, for example, an average, median, or highest relative intracranial pressure value observed during a seizure, a percent change from a baseline value during the seizure, or the time for the intracranial pressure to return to a baseline state after the occurrence of a seizure. In addition to or instead of intracranial pressure, patient motion or posture may be monitored in order to assess the patient's seizure disorder. For example, a seizure type or severity may be determined based on patient motion sensed during a seizure.
    Type: Application
    Filed: January 23, 2009
    Publication date: May 13, 2010
    Applicant: Medtronic, Inc.
    Inventors: Jonathon E. Giftakis, Nina M. Graves, Jonathan C. Werder, Eric J. Panken, Timothy J. Denison, Keith A. Miesel, Michele H. Herzog
  • Publication number: 20100121214
    Abstract: Intracranial pressure of a patient may be monitored in order to evaluate a seizure disorder. In some examples, trends in the intracranial pressure over time may be monitored, e.g., to detect changes to the patient's condition. In addition, in some examples, a seizure metric may be generated for a detected seizure based on sensed intracranial pressures. The seizure metric may indicate, for example, an average, median, or highest relative intracranial pressure value observed during a seizure, a percent change from a baseline value during the seizure, or the time for the intracranial pressure to return to a baseline state after the occurrence of a seizure. In addition to or instead of intracranial pressure, patient motion or posture may be monitored in order to assess the patient's seizure disorder. For example, a seizure type or severity may be determined based on patient motion sensed during a seizure.
    Type: Application
    Filed: January 23, 2009
    Publication date: May 13, 2010
    Applicant: Medtronic, Inc.
    Inventors: Jonathon E. Giftakis, Nina M. Graves, Jonathan C. Werder, Eric J. Panken, Timothy J. Denison, Keith A. Miesel, Michele H. Herzog
  • Patent number: 7684855
    Abstract: A medical device system includes a brain monitoring element, cardiac monitoring element, therapy module and a processor. The processor is configured to activate the therapy module upon detection of a cardiac event in the cardiac signal. The processor is further configured to monitor the brain signal and communicate to the therapy module to change the cardiac triggered therapeutic output to the brain based upon the brain monitoring. A method of treating a person with a neurological disorder is also provided.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: March 23, 2010
    Assignee: Medtronic, Inc.
    Inventors: Jonathon E. Giftakis, Nina M. Graves
  • Publication number: 20090083070
    Abstract: An indication that a patient event occurred may be used to evaluate the efficacy of at least one therapy program and/or adjust therapy delivery to the patient. In some examples, the patient event indication includes patient input that may be received via an event indication button of a programming device. In some examples, therapy delivery may be adjusted by adjusting at least one therapy parameter value, switching therapy programs or therapy program groups or restarting a therapy cycle of a medical device.
    Type: Application
    Filed: September 23, 2008
    Publication date: March 26, 2009
    Inventors: Jonathon E. Giftakis, Peter J. Kovach, Warren W. Ball, Jonathan C. Werder, Nina M. Graves, David C. Ullestad, Sarah B. Alme
  • Publication number: 20090082641
    Abstract: An indication that a patient event occurred may be used to evaluate the efficacy of at least one therapy program and/or adjust therapy delivery to the patient. In some examples, the patient event indication includes patient input that may be received via an event indication button of a programming device. In addition to or instead of the patient input, the patient event indication may be generated based on a physiological parameter of the patient. In some examples, therapy delivery may be adjusted by adjusting at least one therapy parameter value, switching therapy programs or therapy program groups or restarting a therapy cycle of a medical device. The patient input via an event indication button may also help evaluate whether a therapy system is useful for the patient.
    Type: Application
    Filed: September 23, 2008
    Publication date: March 26, 2009
    Applicant: Medtronic, Inc.
    Inventors: Jonathon E. Giftakis, Jonathan C. Werder, Nina M. Graves, David C. Ullestad
  • Publication number: 20090082640
    Abstract: Patient input indicating the occurrence of an event and information relating to the event may be collected by a computing device. In some examples, the patient input is received via an event indication input mechanism of a medical device programmer. A clinician may review the event information to evaluate the efficacy of a therapy system (e.g., a particular therapy program or program group) or a patient's condition. In one example, a patient may activate an event indication input mechanism to indicate the occurrence of a seizure symptom, and input information relating to the seizure, such as the duration, severity, type of seizure or efficacy of a therapy system implemented to manage seizures.
    Type: Application
    Filed: September 23, 2008
    Publication date: March 26, 2009
    Applicant: Medtronic, Inc.
    Inventors: Peter J. Kovach, Warren W. Ball, Sarah B. Alme, Nina M. Graves
  • Publication number: 20080269842
    Abstract: An implantable medical device such as an implantable pulse generator that includes EEG sensing for monitoring and treating neurological conditions, and leadless ECG sensing for monitoring cardiac signals. The device includes a connector block with provisions for cardiac leads which may be used/enabled when needed. If significant co-morbid cardiac events are observed in patients via the leadless ECG monitoring, then cardiac leads may be subsequently connected for therapeutic use.
    Type: Application
    Filed: April 27, 2007
    Publication date: October 30, 2008
    Inventors: Jonathon E. Giftakis, Nina M. Graves, Jonathan C. Werder, Eric J. Panken
  • Patent number: 7282030
    Abstract: Apparatus and method support a repetitive administration of a therapeutic treatment through a delivery unit during a neurological event, such as a seizure, of a nervous system disorder. The medical device system monitors signal data from a sensor and through an amplifier. A neurological event is detected by a medical device system using a detection algorithm. Consequently, a electrical stimulation pulse is applied to an electrode. During the delivery of the electrical stimulation pulse, the medical device system blanks signal data that is associated with the electrode. Subsequently, additional blanking is providing during a time interval in which signal artifacts may occur and the amplifier is stabilizing. The medical device system then collects signal data for the detection algorithm to stabilize. Subsequently, the medical device system collects additional signal data in order to obtain statistically meaningful data.
    Type: Grant
    Filed: October 15, 2003
    Date of Patent: October 16, 2007
    Assignee: Medtronic, Inc.
    Inventors: Mark G. Frei, Ivan Osorio, Naresh C. Bhavaraju, David L. Carlson, Jonathon E. Giftakis, Nina M. Graves
  • Patent number: 7280867
    Abstract: Apparatus and method detect a detection cluster that is associated with a neurological event, such as a seizure, of a nervous system disorder and update therapy parameters that are associated with a treatment therapy. The occurrence of the detection cluster is detected when the maximal ratio exceeds an intensity threshold. If the maximal ratio drops below the intensity threshold for a time interval that is less than a time threshold and subsequently rises above the intensity threshold, the subsequent time duration is considered as being associated with the detection cluster rather than being associated with a different detection cluster. Consequently, treatment of the nervous system disorder during the corresponding time period is in accordance with one detection cluster. Treatment therapy may be provided by providing electrical stimulation, drug infusion or a combination.
    Type: Grant
    Filed: October 15, 2003
    Date of Patent: October 9, 2007
    Assignee: Medtronic, Inc.
    Inventors: Mark G. Frei, Ivan Osorio, Nina M. Graves, Scott F. Schaffner, Mark T. Rise, Jonathon E. Giftakis, David L. Carlson
  • Patent number: 7242983
    Abstract: Apparatuses and methods selectively blank a neurological channel of a medical device system in the treatment of a nervous system disorder. A selected signal of a selected channel may be blanked if it is determined that the selected signal may be affected by an artifact when the medical device system delivers a treatment therapy. The selected signal may be blanked by hardware, in which the selected electrode is disconnected from the selected channel (which may include an selected amplifier) and is connected to a fixed voltage in order to avoid saturation of the selected amplifier. The selected channel may be blanked by software, in which a signal processor is instructed not to process neurological data on the selected channel for a determined time duration. Embodiments may combine hardware and software blanking for the selected signal.
    Type: Grant
    Filed: October 15, 2003
    Date of Patent: July 10, 2007
    Assignee: Medtronic, Inc.
    Inventors: Mark G. Frei, Ivan Osorio, Mark T. Rise, Jonathon E. Giftakis, Nina M. Graves, David L. Carlson, Randy M. Jensen
  • Publication number: 20040158119
    Abstract: Apparatus and method support a neurological event screening for a medical device. The medical device assists a user in determining a configuration of the medical device for delivering an effective treatment for a nervous system disorder. The medical device detects a neurological event, such as a seizure, and reports a neurological event focus location and a neurological event spread to the user. The user may use the information to provide a configuration of a therapeutic delivery unit and associated therapy parameters. Therapeutic treatment is delivered to the patient, and the medical device is provided an indication of the patient's acceptance to the treatment. The user may modify the configuration and therapy parameters in order to achieve efficacy and acceptance. Depending upon the patient's acceptance, therapy is applied in either an open loop mode or a closed loop mode. The medical device determines whether the treatment is successful in accordance with a criterion.
    Type: Application
    Filed: October 15, 2003
    Publication date: August 12, 2004
    Applicant: Medtronic, Inc.
    Inventors: Ivan Osorio, Mark G. Frei, Naresh C. Bhavaraju, Thomas E. Peters, Nina M. Graves, Scott F. Schaffner, Jonathon E. Giftakis, Mark T. Rise, Jonathan C. Werder
  • Publication number: 20040152958
    Abstract: Apparatus and method support a repetitive administration of a therapeutic treatment through a delivery unit during a neurological event, such as a seizure, of a nervous system disorder. The medical device system monitors signal data from a sensor and through an amplifier. A neurological event is detected by a medical device system using a detection algorithm. Consequently, a electrical stimulation pulse is applied to an electrode. During the delivery of the electrical stimulation pulse, the medical device system blanks signal data that is associated with the electrode. Subsequently, additional blanking is providing during a time interval in which signal artifacts may occur and the amplifier is stabilizing. The medical device system then collects signal data for the detection algorithm to stabilize. Subsequently, the medical device system collects additional signal data in order to obtain statistically meaningful data.
    Type: Application
    Filed: October 15, 2003
    Publication date: August 5, 2004
    Applicant: Medtronic, Inc.
    Inventors: Mark G. Frei, Ivan Osorio, Naresh C. Bhavaraju, David L. Carlson, Jonathon E. Giftakis, Nina M. Graves
  • Publication number: 20040138517
    Abstract: Apparatuses and methods support multi-modal operation of a medical device system for a nervous system disorder. The medical device system comprises an implanted component and an external component and supports a first feature and a second feature that are associated with the treatment therapy. The medical device system supports both features when the implanted component and the external component are coupled. If the external component is decoupled, the implanted component continues to support the first feature. Moreover, the embodiment may support a plurality of features during a treatment interval. Another aspect of the invention allows for modularly expanding a medical device system in order to add a feature that enhances existing functionality or that provides additional functionality. In an embodiment, a module that is associated with an external component of the medical device system supports the added feature.
    Type: Application
    Filed: October 15, 2003
    Publication date: July 15, 2004
    Applicant: Medtronic, Inc.
    Inventors: Ivan Osorio, Mark G. Frei, Mark T. Rise, Scott F. Schaffner, Nina M. Graves
  • Publication number: 20040138536
    Abstract: Apparatus and method detect a detection cluster that is associated with a neurological event, such as a seizure, of a nervous system disorder and update therapy parameters that are associated with a treatment therapy. The occurrence of the detection cluster is detected when the maximal ratio exceeds an intensity threshold. If the maximal ratio drops below the intensity threshold for a time interval that is less than a time threshold and subsequently rises above the intensity threshold, the subsequent time duration is considered as being associated with the detection cluster rather than being associated with a different detection cluster. Consequently, treatment of the nervous system disorder during the corresponding time period is in accordance with one detection cluster. Treatment therapy may be provided by providing electrical stimulation, drug infusion or a combination.
    Type: Application
    Filed: October 15, 2003
    Publication date: July 15, 2004
    Applicant: Medtronic, Inc.
    Inventors: Mark G. Frei, Ivan Osorio, Nina M. Graves, Scott F. Schaffner, Mark T. Rise, Jonathon E. Giftakis, David L. Carlson
  • Publication number: 20040133248
    Abstract: Apparatuses and methods selectively blank a neurological channel of a medical device system in the treatment of a nervous system disorder. A selected signal of a selected channel may be blanked if it is determined that the selected signal may be affected by an artifact when the medical device system delivers a treatment therapy. The selected signal may be blanked by hardware, in which the selected electrode is disconnected from the selected channel (which may include an selected amplifier) and is connected to a fixed voltage in order to avoid saturation of the selected amplifier. The selected channel may be blanked by software, in which a signal processor is instructed not to process neurological data on the selected channel for a determined time duration. Embodiments may combine hardware and software blanking for the selected signal.
    Type: Application
    Filed: October 15, 2003
    Publication date: July 8, 2004
    Applicant: Medtronic, Inc.
    Inventors: Mark G. Frei, Ivan Osorio, Mark T. Rise, Jonathon E. Giftakis, Nina M. Graves, David L. Carlson, Randy M. Jensen
  • Publication number: 20040133119
    Abstract: A medical device system capable of scoring a severity of sensed neurological signals relating to a nervous system disorder. The system comprises a monitoring element that receives a neurological signal having at least one event to be scored. The medical device system identifies one or more features of the neurological signal to use in scoring and computes a score of relative severity of the event using the identified feature. Once two or more events have been scored, the events may be ranked by severity relative to each other.
    Type: Application
    Filed: October 15, 2003
    Publication date: July 8, 2004
    Applicant: Medtronic, Inc.
    Inventors: Ivan Osorio, Mark G. Frei, Nina M. Graves, Jonathon E. Giftakis